{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T02:38:38Z","timestamp":1784774318757,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Our aim was to identify predictors of mortality and limb loss in iatrogenic and civilian arterial trauma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases were identified by searching prospectively maintained registries. Multivariable logistic regression was used to identify independent outcome predictors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 285 patients with arterial trauma were managed with endovascular (<jats:italic>n<\/jats:italic>\u2009=\u200920) or open (<jats:italic>n<\/jats:italic>\u2009=\u2009265) repair. Iatrogenic injuries increased in frequency during the course of the study, from 23.9% during the first decade to 35.9 and 55.7% during the second and third decade, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Endovascular management increased in frequency during the course of the study, from 0% during the first decade to 5.1 and 11.1% during the second and third decade, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.005). Mortality was 9.8%, and limb loss (in cases with injury of the aorta or limb arteries, <jats:italic>n<\/jats:italic>\u2009=\u2009259) was 6.2%. Independent predictors of mortality included increased age (odds ratio, 95% confidence interval [OR, 95% CI] 1.05 (1.02\u20131.07), <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), blunt trauma (OR [95% CI] 4.8 (1.9\u201312.2), <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and the number of RBC units transfused intraoperatively (OR [95% CI] 1.25 (1.1\u20131.4), <jats:italic>p<\/jats:italic>\u2009=\u20090.001). Independent predictors of limb loss included the first half of the study period (OR [95% CI] 3.9 (1.1\u201314.1), <jats:italic>p<\/jats:italic>\u2009=\u20090.04), lower extremity arterial trauma (vs upper extremity, aortic, common or external iliac artery trauma, OR [95% CI] 8.3 (1.9\u201335.7), <jats:italic>p<\/jats:italic>\u2009=\u20090.004), bone fracture (OR [95% CI] 16.9 (4.7\u201362.5), <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and the number of RBC units transfused intraoperatively (OR [95% CI] 1.16 (1.02\u20131.33), <jats:italic>p<\/jats:italic>\u2009=\u20090.024).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Increasingly iatrogenic in cause and managed by endovascular methods, arterial trauma remains a problem associated with significant mortality and limb loss. Identification of unfavourable outcome predictors may help clinicians involved with arterial trauma to escalate the level of care.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05792-9","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T17:02:50Z","timestamp":1601053370000},"page":"160-167","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Outcome Predictors in Civilian and Iatrogenic Arterial Trauma"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7516-4873","authenticated-orcid":false,"given":"Stavros K.","family":"Kakkos","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery University of Patras Medical School Patras Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minos","family":"Tyllianakis","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery University of 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