{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:29:04Z","timestamp":1790389744312,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Roma La Sapienza"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The pneumoperitoneum to treat prolonged air leaks or pleural space problems after pulmonary resection has been successfully used for decades. The aim of the study is to describe our experience with the early induction of therapeutic pneumoperitoneum (TP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the data of 103 consecutive patients undergoing TP between September 2011 and September 2019. Patients were divided into two groups according to the time of the induction of TP: early application (\u226572 h) and standard application (&gt;72 h).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 52 early TP and 51 standard TP were analyzed. The median time of TP induction was 2 (1\u20133) versus 8 (5\u201311) postoperative days (POD) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The time for obliteration of the residual pleural space (7 vs.9\u00a0days, <jats:italic>p<\/jats:italic>\u2009=\u20090.805) and the time of resolution of the air leaks (14 vs. 16\u00a0days, <jats:italic>p<\/jats:italic>\u2009=\u20090.663) didn't differ between the two groups, but a favorable trend was observed in the early group. The hospital stay was lower for patients undergoing early pneumoperitoneum: 9 versus 18\u00a0days (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The multivariate analysis showed that POD of induction of TP (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), time of resolution of the air leak (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and Heimlich valve (<jats:italic>p<\/jats:italic>\u2009=\u20090.002) were independent variables associated with the hospital stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of TP whenever a space problem or air leaks occur after pulmonary resections is safe and effective. Its early use (\u226472 h) accelerates the hospital stay, eventually reducing the time of resolution of the air leak and residual pleural space.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05813-7","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T18:02:58Z","timestamp":1602784978000},"page":"624-630","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early Induction of Bedside Pneumoperitoneum in the Management of Residual Pleural Space and Air Leaks After Pulmonary Resection"],"prefix":"10.1002","volume":"45","author":[{"given":"Alessandra","family":"Pecoraro","sequence":"first","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3373-0328","authenticated-orcid":false,"given":"Giovanni Maria","family":"Garbarino","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Peritore","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Tiracorrendo","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Andreetti","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erino Angelo","family":"Rendina","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Mercantini","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Science and Translational Medicine Sapienza University of Rome, Sant'Andrea Hospital Via di Grottarossa 1035\u201039, 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","unstructured":"KorasidisS AndreettiC D\u2019AndrilliA IbrahimM CicconeA PoggiCet al. Management of residual pleural space and air leaks after major pulmonary resection.Interact Cardiovasc Thorac Surg(2010)10.1510\/icvts.2009.23124120479074","DOI":"10.1510\/icvts.2009.231241"},{"key":"e_1_2_9_3_1","unstructured":"RiceTW OkerekeIC BlackstoneEHPersistent air\u2010leak following pulmonary resection.Chest Surg Clin of North America(2002)10.1016\/S1052\u20103359(02)00022\u20104"},{"issue":"3","key":"e_1_2_9_4_1","first-page":"39","article-title":"Definition of postresectional residual pleural space","volume":"50","author":"Solak O","year":"2007","journal-title":"Can J Surg"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","unstructured":"MisthosP KokotsakisJ KonstantinouM SkottisI LiouliasAPostoperative residual pleural spaces: characteristics and natural history.Asian Cardiovasc Thorac Ann(2007)10.1177\/02184923070150011217244924","DOI":"10.1177\/021849230701500112"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"585","article-title":"Natural history of residual air spaces after pulmonary resection","volume":"6","author":"Barker WL","year":"1996","journal-title":"Chest Surg Clin of North America"},{"issue":"6","key":"e_1_2_9_7_1","first-page":"887","article-title":"Postoperative pneumoperitoneum for prolonged air leaks and residual spaces after pulmonary resections","volume":"40","author":"Carbognani P","year":"1999","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","unstructured":"OkurE ArisoyY BaysungurV GokceM SevilgenG ErgeneGet al. 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Pneumoperitoneum for the management of pleural air space problems associated with major pulmonary resections.Ann Thorac Surg(2001)10.1016\/S0003\u20104975(01)03050\u2010811722070"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","unstructured":"AbolhodaA LiuD BrooksA BurtMProlonged air leak following radical upper lobectomy: an analysis of incidence and possible risk factors.Chest(1998)10.1378\/chest.113.6.15079631785","DOI":"10.1378\/chest.113.6.1507"},{"key":"e_1_2_9_12_1","unstructured":"PodgaetzE BergerJ SmallJ GarzaR AndradeRTherapeutic pneumoperitoneum: relevant or obsolete in 2015?.Thorac Cardiovasc Surg(2017)10.1055\/s\u20100035\u2010157114026757212"},{"key":"e_1_2_9_13_1","unstructured":"MularskiRA SippelJM OsborneMLPneumoperitoneum: A review of nonsurgical causes.Crit Care Med(2000)10.1097\/00003246\u2010200007000\u20100007810921609"},{"key":"e_1_2_9_14_1","unstructured":"NielsenKT LundL LarsenLPS KnudsenPDuration of postoperative pneumoperitoneum.Eur J Surg(1997)10.1097\/00005392\u2010199804000\u2010001399248983"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-020-05813-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00268-020-05813-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-020-05813-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-020-05813-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,7]],"date-time":"2024-01-07T17:45:49Z","timestamp":1704649549000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-020-05813-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,15]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1007\/s00268-020-05813-7"],"URL":"https:\/\/doi.org\/10.1007\/s00268-020-05813-7","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,15]]},"assertion":[{"value":"28 September 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}