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The majority of arterial and venous interventions have converted from open surgery to minimally invasive percutaneous endovascular procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This surgical innovations symposium article reviews current endovascular therapy in multiple vascular beds with a primary focus on carotid artery occlusive disease, aortic pathologies, and lower extremity arterial occlusive disease. Mesenteric arterial occlusive disease and lower extremity venous endovascular therapies are also briefly discussed. Indications for intervention, treatment examples and outcomes analysis are presented. While not reviewed in this article, endovascular therapy has also become first line in the treatment of coronary artery disease, chronic mesenteric arterial occlusive disease, superficial venous reflux, central vein occlusion, and acute venous thrombus intervention when indicated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Endovascular therapies are used in all vascular beds to treat the full spectrum of vascular pathologies. Aneurysm disease, atherosclerotic arterial occlusive disease, acute arterial and venous thrombosis, ongoing hemorrhage, and venous reflux are among the issues which can be addressed by endovascular means. The minimally invasive nature of endovascular treatments in what is largely a very co\u2010morbid patient cohort is an attractive method of avoiding major procedural related morbidity and mortality.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05875-7","type":"journal-article","created":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T17:02:36Z","timestamp":1606064556000},"page":"3493-3502","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["\u201cModern Endovascular Therapy\u201d"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-9791","authenticated-orcid":false,"given":"Matthew","family":"Blecha","sequence":"first","affiliation":[{"name":"Division of Vascular Surgery and Endovascular Therapy, Department of Surgery Loyola University Medical Center 2160 S. 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