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Despite limitations to surgical care access, health\u2010related quality of life (HRQoL) data following surgical intervention are scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a 3\u2010month prospective observational study of adult patients undergoing an abdominal operation. We administered the Patient\u2010Reported Outcome Measurement Information System (PROMIS)\u201025 and Index of Independence in Activities of Daily Living questionnaire preoperatively (to postoperative day [POD] #1), POD#7, and POD#30. PROMIS\u201025 HRQoL domains were measured and converted to standardized T\u2010scores (median 50, minimal important clinical difference 3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 117 laparotomy patients who were enrolled, 89 (76.1%) were male with a median age of 39 years (IQR 27\u201354). Operations were primarily for intestinal volvulus (<jats:italic>n<\/jats:italic>\u2009=\u200930, 28.3%) and intestinal perforation (<jats:italic>n<\/jats:italic>\u2009=\u200929, 27.4%). We completed a total of 80 (68.4%), 95 (81.2%), and 77 (65.8%) surveys preoperatively, at POD#7, and POD#30, respectively. Preoperatively patients showed high median levels of anxiety (56), depression (60), fatigue (63), and pain interference (62), which all improved postoperatively. Mobility was poor preoperatively (31) and showed improvement during recovery but remained poor [POD#7: 32, POD#30: 39]. Pain intensity was high (10\/10) preoperatively and improved to 3\/10 by POD#30. Patients with complications compared to those without had clinically significant worse HRQoL in all domains measured by POD#30.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Abdominal surgery patients in a resource\u2010limited setting present with poor HRQoL, which improves postoperatively. Mobility remained poor throughout follow\u2010up despite improved pain scores. Our findings highlight the need for improved HRQoL and pain control among surgical patients.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-021-06050-2","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T15:04:25Z","timestamp":1616511865000},"page":"1971-1978","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Patient\u2010Reported Quality of Life Following Laparotomy in a Resource\u2010Limited Setting"],"prefix":"10.1002","volume":"45","author":[{"given":"Laura N.","family":"Purcell","sequence":"first","affiliation":[{"name":"Department of Surgery University of North Carolina at Chapel Hill Chapel Hill USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Reiss","sequence":"additional","affiliation":[{"name":"School of Medicine University of North Carolina at Chapel Hill 4008 Burnett Womack Building 7228 Chapel Hill CB USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercy","family":"Mtalimanja","sequence":"additional","affiliation":[{"name":"University of North Carolina Project\u2010Malawi Lilongwe Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Kuyenda","sequence":"additional","affiliation":[{"name":"University of North Carolina Project\u2010Malawi Lilongwe Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Msosa","sequence":"additional","affiliation":[{"name":"Kamuzu Central Hospital Lilongwe Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine D.","family":"Westmoreland","sequence":"additional","affiliation":[{"name":"University of North Carolina Project\u2010Malawi Lilongwe Malawi"},{"name":"Pediatric Hematology\u2010Oncology University of North Carolina at Chapel Hill Chapel Hill USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Charles","sequence":"additional","affiliation":[{"name":"Department of Surgery University of North Carolina at Chapel Hill Chapel Hill USA"},{"name":"School of Medicine University of North Carolina at Chapel Hill 4008 Burnett Womack Building 7228 Chapel Hill CB USA"},{"name":"Kamuzu Central Hospital Lilongwe Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050121"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010008\u20109525\u20109"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000200"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010016\u20103614\u2010y"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(15)60829\u20107"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.03.003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7299.1417"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010018\u20104778\u20104"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000676"},{"key":"e_1_2_9_11_1","unstructured":"The World Bank.GDP per capita \u2010 Malawi. 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