{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:41:33Z","timestamp":1762868493464,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T00:00:00Z","timestamp":1619136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T00:00:00Z","timestamp":1619136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T00:00:00Z","timestamp":1619136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Regionalization of sarcoma care may improve outcomes. Concerns exist regarding the burdens of travel and its effects on care. We evaluate the presence of a \u201cdistance bias\u201d.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study of patients with extremity soft tissue sarcoma (stage I\u2010III) within the NCDB. Travel distance (TD) and hospital volume (VOL) were categorized into quartiles. Alternating statistical models were used for analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>1,035 hospitals contributed 11,979 cases. Median and maximum VOL were 5 and 45 cases\/year. VOL quartiles were \u201clow\u2010volume\u201d (LV) (892 hospitals,\u2009&lt;\u20093 cases\/yr.), \u201cintermediate low\u2010volume\u201d (ILV) (89, 3\u20135 cases\/yr.), \u201cintermediate high\u2010volume\u201d (IHV) (39, 6\u201312 cases\/yr.), and \u201chigh\u2010volume\u201d (HV) (15,\u2009&gt;\u200912 cases\/yr.). TD quartiles: \u201cshort\u2010travel\u201d (ST) (&lt;\u20098\u00a0mi), \u201cintermediate\u2010short travel\u201d (IST) (8\u201317), \u201cintermediate long\u2010travel\u201d (ILT) (18\u201349), and \u201clong\u2010travel\u201d (LT) (&gt;\u200950). VOL but not TD is associated with improved survival [HR 0.65 (CI 0.52\u20130.83)] and rate of R0 resection [1.87 (CI 1.4\u20132.5)] but has no effect on amputation rates. Matched analyses demonstrate similar results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Hospital volume but not distance traveled to treatment facility is associated with improved survival and R0 resections for extremity soft tissue sarcomas. Despite the inconveniences of travel, patients may benefit from treatment at high volume centers.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-021-06109-0","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T20:20:19Z","timestamp":1619295619000},"page":"2415-2425","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Traveling to Receive Treatment for Extremity Soft Tissue Sarcomas: Is it worth the drive?"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0912-5259","authenticated-orcid":false,"given":"Roberto J.","family":"Vidri","sequence":"first","affiliation":[{"name":"Harvard T.H. Chan School of Public Health Boston MA USA"},{"name":"Department of Surgery Tufts University School of Medicine\/Maine Medical Center Portland ME USA"},{"name":"Department of Surgery Fox Chase Cancer Center 333 Cottman Ave C308 19111 Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandrajit P.","family":"Raut","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery Brigham and Women's Hospital, Center for Sarcoma and Bone Oncology, Dana\u2010Farber Cancer Institute, Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy L.","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Department of Surgery Tufts University School of Medicine\/Maine Medical Center Portland ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,23]]},"reference":[{"volume-title":"SEER Stat Fact 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