{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:47:54Z","timestamp":1762660074775},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The objective of this study was to describe the detailed technique and clinical outcomes of portal vein embolization via the round ligament (RL\u2010PVE) prior to major hepatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2010 and March 2020, a total of 50 portal vein embolization (PVE) procedures were performed in 50 patients. Of them, seven patients who underwent RL\u2010PVE were enrolled in this study. Percutaneous transhepatic portal vein embolization (PTPE) was not indicated due to the following reasons: bile duct dilation (<jats:italic>n<\/jats:italic>\u2009=\u20094), difficulty in visualizing the portal vein on ultrasonography because of severe fatty liver (<jats:italic>n<\/jats:italic>\u2009=\u20091), large tumor size (<jats:italic>n<\/jats:italic>\u2009=\u20091), and combined surgery with staging laparoscopy (<jats:italic>n<\/jats:italic>\u2009=\u20091). The following were reasons for avoiding trans\u2010ileocecal PVE: past laparotomy (<jats:italic>n<\/jats:italic>\u2009=\u20095), difficulty in accessing the portal vein due to a large tumor (<jats:italic>n<\/jats:italic>\u2009=\u20091), and purpose of preventing small intestinal adhesions before hepatopancreatoduodenectomy (<jats:italic>n<\/jats:italic>\u2009=\u20091). The percentage of functional hepatic remnant rates was calculated before and after RL\u2010PVE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Technical success was achieved in all cases. Five patients underwent embolization of the right portal vein, while two underwent embolization of the left portal vein. The median operative time and blood loss during RL\u2010PVE were 181\u00a0min and 33 g, respectively. Morbidity and mortality related to RL\u2010PVE were not observed. The median functional hepatic remnant rate before and after PVE was 55.6% and 63.2%, respectively. Liver functions including Child\u2013Pugh classification were equivalent before and after RL\u2010PVE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The RL\u2010PVE technique may be useful in elective cases for which it is difficult to safely perform PTPE or trans\u2010ileocecal approaches.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-021-06145-w","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T16:04:28Z","timestamp":1622736268000},"page":"2878-2885","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Novel Approach via the Round Ligament in Portal Vein Embolization"],"prefix":"10.1002","volume":"45","author":[{"given":"Takanobu","family":"Yamao","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, GraduateSchool of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromitsu","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Takematsu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Higashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Yamamura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsunori","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yo\u2010ichi","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, GraduateSchool of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences Kumamoto University 1\u20101\u20101, Honjo, Chuo\u2010ku 860\u20108556 Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.10.023"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21928"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2019.02.023"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2015.16.5.1079"},{"key":"e_1_2_7_6_1","first-page":"2297","article-title":"Role of portal vein embolization in hepatobiliary malignancy","volume":"54","author":"Sirichindakul B","year":"2007","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.41.220.597"},{"key":"e_1_2_7_8_1","first-page":"567","article-title":"The fate of human umbilical cord vessels used as interposition arterial grafts in the baboon","volume":"140","author":"Dardik II","year":"1975","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12835"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23716"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072\u20107515(99)00288\u20104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i34.7851"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2006.08.021"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2011.08.007"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(67)90400\u2010X"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2017.01.016"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0284185115590285"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.06.013"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20103786\u20103"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ssu.2980090404"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010013\u20102237\u2010y"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2014.15.5.630"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2009.05.041"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335718"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31815f6e5b"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270\u2010012\u20100440\u2010y"},{"key":"e_1_2_7_27_1","first-page":"1265","article-title":"Transileocolic portal vein embolization","volume":"76","author":"Kobayashi A","year":"2014","journal-title":"Geka"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-021-06145-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00268-021-06145-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-021-06145-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-021-06145-w","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T16:13:43Z","timestamp":1703348023000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-021-06145-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,3]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1007\/s00268-021-06145-w"],"URL":"https:\/\/doi.org\/10.1007\/s00268-021-06145-w","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,3]]},"assertion":[{"value":"18 April 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the ethical committee of our institute and registered with the committee number 1084.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Approval of research by the ethics committee"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}