{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:22:04Z","timestamp":1781886124053,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Postoperative symptoms and pain after laparoscopic cholecystectomy (LC) are common in women. However, there is no evidence of differences in incidence and severity among different age groups. We evaluated whether adverse postoperative symptoms were more common in younger than in older women after LC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and fifty premenopausal (mean age 37.6\u2009\u00b1\u20093.6 y) and 145 postmenopausal women (59\u2009\u00b1\u20095.2 y) were included in this retrospective cohort study. Clinical and anthropometric parameters were analyzed. Study endpoints were the incidences of postoperative nausea and vomiting (PONV) and pain, and the additional analgesics and antiemetics needed after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Body mass index was normal in 42.7% of patients in the younger group and 64.8% in the older group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Reported pain was more frequent and intense in the younger group throughout the study period (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Additional narcotics were required in 18% of premenopausal versus 7.6% of postmenopausal women (<jats:italic>P<\/jats:italic>\u2009=\u20090.001), and the doses used to reduce pain were higher for premenopausal women (<jats:italic>P<\/jats:italic>\u2009=\u20090.02). PONV was more frequent in the younger group at 1 and 6 h after surgery (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005). Rescue antiemetics were required in 29 premenopausal and 13 postmenopausal women (<jats:italic>P<\/jats:italic>\u2009=\u20090.01). Hospital stay was shorter for the older patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.01). Minor morbidity was observed in both groups (0.7% and 2.1%). There was no mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early PONV and pain after LC were more frequent in premenopausal women, who also required more rescue analgesic and antiemetic medication.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-021-06367-y","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T14:10:53Z","timestamp":1636121453000},"page":"356-361","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Differences in Postoperative Pain, Nausea, and Vomiting After Elective Laparoscopic Cholecystectomy in Premenopausal and Postmenopausal Mexican Women"],"prefix":"10.1002","volume":"46","author":[{"given":"Guillermo","family":"Medina\u2010Diaz\u2010Cort\u00e9s","sequence":"first","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma Valeria","family":"Brancaccio\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Esparza\u2010Estrada","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Jos\u00e9","family":"Barbosa\u2010Camacho","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clotilde","family":"Fuentes\u2010Orozco","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola Guadalupe","family":"Gonz\u00e1lez\u2010Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan Mat\u00edas","family":"Chejfec\u2010Ciociano","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Vinicio","family":"Ram\u00edrez\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica Alexandra","family":"S\u00e1nchez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Olivia","family":"Cort\u00e9s\u2010Flores","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Socorro","family":"\u00c1lvarez\u2010Villase\u00f1or","sequence":"additional","affiliation":[{"name":"Medical Auxiliary Coordination of Health Research Mexican Institute of Social Security Calle Francisco I. Madero 315 23020 La Paz Baja California Sur Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Ch\u00e1vez\u2010Tostado","sequence":"additional","affiliation":[{"name":"Department of Human Reproduction Health Sciences University Center, Universidad de Guadalajara Calle Hospital 320 44280 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Cervantes\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hospital Civil de Guadalajara Fray Antonio Alcalde Calle Hospital 278 44280 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabino","family":"Cervantes\u2010Guevara","sequence":"additional","affiliation":[{"name":"Department of Welfare and Sustainable Development University Center of the North University of Guadalajara Carretera Federal 23, Km 191 46200 Colotl\u00e1n Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo Alonso","family":"Cervantes\u2010Cardona","sequence":"additional","affiliation":[{"name":"Department of Philosophical, Methodological and Instrumental Disciplines, Health Sciences University Center University of Guadalajara Sierra Mojada 950 44340 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Gonz\u00e1lez\u2010Ojeda","sequence":"additional","affiliation":[{"name":"Biomedical Research Unit 02. Specialties Hospital, Western Medical Center Mexican Institute of Social Security Avenida Belisario Dom\u00ednguez 1000 44430 Guadalajara Jalisco Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,3]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"48","article-title":"[Epidemiology of gallstone disease in Mexico]","volume":"42","author":"M\u00e9ndez S\u00e1nchez N","year":"1990","journal-title":"Rev Invest Clin"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01316800"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/lps.1995.5.289"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000219597.16143.4D"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aes276"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000068822.10113.9e"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2020.08.012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007618"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genm.2009.03.006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/204946370800200206"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/693912"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181577511"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14569"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010020\u201005744\u20103"},{"key":"e_1_2_9_16_1","first-page":"2430","article-title":"The big \u201clittle problem\u201d","volume":"73","author":"Kapur PA","year":"1991","journal-title":"Anesth Analg"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.09.028"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u20104939\u20103127\u20109_1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540\u2010011\u20101274\u20105"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1990.56"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.8.606"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2015.68.6.581"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540\u2010020\u201002781\u2010z"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-021-06367-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00268-021-06367-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-021-06367-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-021-06367-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T17:53:44Z","timestamp":1703354024000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-021-06367-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,3]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1007\/s00268-021-06367-y"],"URL":"https:\/\/doi.org\/10.1007\/s00268-021-06367-y","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,3]]},"assertion":[{"value":"24 October 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no financial or other conflicts of interest. All authors declare that they comply with the ethical policies of the journal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the institutional Ethics and Research Committees of the Specialties Hospital, Western Medical Center, Mexican Institute of Social Security (R-2020\u20131301-173). The study was carried out respecting the principles of the 1989 Declaration of Helsinki and its amendments according to the Mexican Health Guidelines. The Ethics and Research Committees of the Specialties Hospital of the Mexican Institute of Social Security in Jalisco, Mexico, approved all protocols (registration number R-2020\u20131301-173).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}