{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:58:41Z","timestamp":1792616321725,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Inadvertent injury of the recurrent laryngeal nerve can occur during radiofrequency ablation (RFA) of thyroid nodules. Methods to avoid permanent injury have not been described. Laryngeal ultrasonography (LUSG) can assess the function of vocal cords (VCs) in real time. The present study aimed to evaluate the feasibility and accuracy of LUSG in assessing real\u2010time VC function during RFA of benign thyroid nodules.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients undergoing RFA for benign thyroid nodules under local anesthesia were included. Spontaneous VC movements were checked with intra\u2010operative LUSG (iLUSG) following each transverse ablation plane. In case of reduced VC movement, the ablation was stopped immediately. Post\u2010ablation VC function was rechecked by LUSG on day\u20100 and flexible laryngoscopy (FL) on day\u20107. A concordance with day\u20100\u00a0LUSG or day\u20107 FL was a \u201ctrue positive\u201d or \u201ctrue negative\u201d depending on the presence or absence of VC palsy (VCP). Accuracy was calculated as the sum of all true positives and negatives divided by total nerves\u2010at\u2010risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 65 eligible patients, 56 (86.2%) were females. Twelve (18.5%) patients had bilateral lobe RFA, while 53 (81.5%) had unilateral RFA. The total number of nerves\u2010at\u2010risk was 77. Three unilateral VCPs (3.9%) were initially detected on iLUSG and confirmed by day\u20100\u00a0LUSG. All recovered fully within one week. The overall accuracy of iLUSG was 100%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>iLUSG is a highly accurate method that permits real\u2010time feedback on the function of the VCs during RFA procedure. Real\u2010time detection of VCP may prevent permanent injury. Methodological routine use of iLUSG is recommended during thyroid RFA.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06596-9","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T20:08:43Z","timestamp":1653077323000},"page":"2206-2211","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Using Intra\u2010Operative Laryngeal Ultrasonography as a Real\u2010Time Tool in Assessing Vocal Cord Function During Radiofrequency Ablation of the Thyroid Gland"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2812-0616","authenticated-orcid":false,"given":"Matrix Man Him","family":"Fung","sequence":"first","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery the University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Hong Kong, SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9362-0086","authenticated-orcid":false,"given":"Brian Hung Hin","family":"Lang","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery the University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Hong Kong, SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2018.19.4.632"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003930"},{"key":"e_1_2_11_4_1","unstructured":"National institute for health and care excellence(2016) Ultrasound\u2010guided percutaneous radiofrequency ablation for benign thyroid nodules. 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