{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T09:31:16Z","timestamp":1773480676567,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the value of ultrasound\u2010guided vacuum\u2010assisted excision (US\u2010guided VAE) in the treatment of intraductal papillomas, including intraductal papillomas with atypical ductal hyperplasia (ADH), and to evaluate the lesion characteristic features affecting the local recurrence rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Between August 2011 and December 2020, 91 lesions of 91 patients underwent US\u2010guided VAE and were diagnosed with intraductal papilloma with or without ADH. The recurrence rate of intraductal papilloma was evaluated on follow\u2010up US. The lesion characteristic features were analyzed to identify the factors affecting the local recurrence rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The local recurrence rate of intraductal papillomas removed by US\u2010guided VAE was 7.7% (7\/91), with the follow\u2010up duration 12\u201392\u00a0months (37.4\u2009\u00b1\u200923.9\u00a0months). Of the 91 patients, five cases diagnosed as intraductal papilloma with ADH did not recur, with the follow\u2010up time 12\u201347\u00a0months (26.4\u2009\u00b1\u200914.4\u00a0months). There were no malignant transformation in all 91 cases during the follow\u2010up period. All 7 patients recurred 7\u201358\u00a0months (22.8\u2009\u00b1\u200919.2\u00a0months) after US\u2010guided VAE. There were no significant differences between the non\u2010recurrence and recurrence groups in terms of age, side, distance from nipple, lesion size, BI\u2010RADS category, with ADH, or history of excision (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>US\u2010guided VAE is an effective method for the treatment of intraductal papilloma, including intraductal papilloma with ADH. It avoids invasive surgical excision, but regular follow\u2010up is recommended to prevent recurrence or new onset due to multifocality. Any suspicious lesions during the follow\u2010up should be actively treated.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06735-2","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T18:18:02Z","timestamp":1673288282000},"page":"699-706","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ultrasound\u2010Guided Vacuum\u2010Assisted Excision to Treat Intraductal Papilloma"],"prefix":"10.1002","volume":"47","author":[{"given":"Ping","family":"He","sequence":"first","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Tao","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of General Surgery Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Wei","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010Mei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of General Surgery Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Gang","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428\u2010021\u201003182\u20107"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","unstructured":"LiX Febres\u2010AldanaC ZhangH ZhangX UraizeeI TangP(2021) Updates on lobular neoplasms papillary adenomyoepithelial and fibroepithelial lesions of the breast.Arch Pathol Lab Med.","DOI":"10.5858\/arpa.2021-0091-RA"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015\u20100092\u2010RA"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2017.10.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010019\u201005266\u20107"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010018\u201004892\u2010x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180250"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.13342"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.12180"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.12283"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.09.018"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-022-06735-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00268-022-06735-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-022-06735-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-022-06735-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T17:21:43Z","timestamp":1703352103000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-022-06735-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,9]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1007\/s00268-022-06735-2"],"URL":"https:\/\/doi.org\/10.1007\/s00268-022-06735-2","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,9]]},"assertion":[{"value":"1 August 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This retrospective study was approved by our institutional review board, and the requirement to obtain informed consent was waived.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}