{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:01:05Z","timestamp":1788321665773,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hyperparathyroidism is common in patients with end\u2010stage kidney disease and may persist after kidney transplantation (KT). Parathyroidectomy (PTx) is curative, but whether PTx should be performed before or after KT remains controversial. There is concern that PTx can adversely affect renal allograft function if performed post\u2010KT and result in persistent hypocalcemia. This study evaluated outcomes and postoperative complications of PTx before and after KT at our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective review of patients at our center (1\/2012\u20132\/2019) who had PTx either pre\u2010KT or post\u2010KT. Data on patient demographics, surgical outcomes, and postoperative complications of PTx were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010eight patients were included in this study, with 23 patients undergoing PTx before KT and 75 after KT. The length of follow\u2010up after KT was 67.7\u2009\u00b1\u200925.5\u00a0months. In post\u2010KT PTx patients, 30\u2010day allograft function was unchanged after PTx. Calcium oxalate and phosphate crystals were less common on allograft biopsies in pre\u2010KT PTx patients (10.0% vs. 34.8%, <jats:italic>p<\/jats:italic>\u2009=\u20090.038). Patients in the pre\u2010KT group required more calcium supplementation after PTx than the post\u2010KT group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). At one\u2010year post\u2010PTx, 17 (19.1%) patients required\u2009&gt;\u20091000\u00a0mg elemental calcium per day and 7 (7.9%) patients required\u2009&gt;\u20092000\u00a0mg\/day. There was no difference in surgical success or postoperative complications between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Parathyroidectomy before or after kidney transplantation does not adversely affect allograft function. The incidence of persistent hypocalcemia was low. Parathyroidectomy is safe and effective either before or after kidney transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06757-w","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T14:15:40Z","timestamp":1665756940000},"page":"319-329","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Making the Cut: Parathyroidectomy Before or After Kidney Transplantation?"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3790-7840","authenticated-orcid":false,"given":"Rongzhi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Surgery The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faaiz","family":"Saad","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Alabama at Birmingham 1670 University Blvd 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Chandler","family":"McLeod","sequence":"additional","affiliation":[{"name":"Department of Surgery The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifton","family":"Kew","sequence":"additional","affiliation":[{"name":"Department of Medicine The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Medicine The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Wille","sequence":"additional","affiliation":[{"name":"Department of Medicine The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayme E.","family":"Locke","sequence":"additional","affiliation":[{"name":"Department of Surgery The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgery The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Medicine The University of Alabama at Birmingham 1808 7th Avenue South 35233 Birmingham AL 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