{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:50:48Z","timestamp":1791888648716,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009336","name":"Bengt Ihres Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009336","name":"Bengt Ihres Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acute cholecystectomy is standard treatment for acute cholecystitis. However, many patients are still treated conservatively and undergo delayed elective surgery. The aim of this study was to determine the ideal time to perform an elective cholecystectomy after acute cholecystitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients treated for acute cholecystitis in Sweden between 2006 and 2013 were identified through the Swedish Patient Register. This cohort was cross\u2010linked with the Swedish Register for Gallstone Surgery, GallRiks, where information on surgical outcome was retrieved. The impact of the time interval after discharge from hospital to elective surgery was analysed by multivariate logistic regression adjusting for gender and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After exclusion of patients not subjected to surgery, not registered in GallRiks and patients treated with acute cholecystectomy, 8532\u00a0remained. This cohort was divided into six\u2010time categories. Using the first time interval\u2009&lt;\u200911\u00a0days from discharge to elective surgery as the reference category the chance of completing surgery with a minimally invasive technique was increased for all categories (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The risk for perioperative complication and cystic duct leakage was reduced if surgery was undertaken\u2009&gt;\u200930\u00a0days after discharge (both <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The risk for bile duct injury was significantly increased if the procedure was undertaken\u2009&gt;\u2009365\u00a0days after discharge (<jats:italic>p<\/jats:italic>\u2009=\u20090.030). The chance of completing the procedure within 100\u00a0min was not affected by time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For patients undergoing elective cholecystectomy after acute cholecystitis, the safety of the procedure increases if surgery is performed more than 30\u00a0days after discharge from the primary admission.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06772-x","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T22:02:46Z","timestamp":1666648966000},"page":"152-161","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Timing of Elective Cholecystectomy After Acute Cholecystitis: A Population\u2010based Register Study"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7960-0962","authenticated-orcid":false,"given":"Agnieszka","family":"Popowicz","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Intervention and Technology (CLINTEC), Trauma and Emergency Surgery Karolinska Institute, Karolinska University Hospital SE\u2010141 52 Solna Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Enochsson","sequence":"additional","affiliation":[{"name":"Department of Surgical and Perioperative Sciences, Surgery Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Sandblom","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Department of Surgery, S\u00f6dersjukhuset Karolinska Institute, Stockholm Solna Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,24]]},"reference":[{"issue":"6","key":"e_1_2_8_2_1","first-page":"CD005440","article-title":"Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis","volume":"2013","author":"Gurusamy KS","year":"2013","journal-title":"Cochrane Database Syst 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