{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T15:20:48Z","timestamp":1782487248656,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004482","name":"Kuwait University","doi-asserted-by":"publisher","award":["Grant number ZM02\/18"],"award-info":[{"award-number":["Grant number ZM02\/18"]}],"id":[{"id":"10.13039\/501100004482","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004482","name":"Kuwait University","doi-asserted-by":"publisher","award":["ZM02\/18"],"award-info":[{"award-number":["ZM02\/18"]}],"id":[{"id":"10.13039\/501100004482","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Topical agents are sometimes applied to surgical wounds after closure; these may include antiseptics or antibiotics. Minimal research has been undertaken to investigate the effect of topical regimens on the tensile strength of suture materials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the effect of four commonly used wound care regimens on the tensile strength of suture materials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The failure load of 9 different suture materials was tested using the Instron Electroplus E3000 tensile testing machine (Instron Corporation, Norwood, Massachusetts). Tensile strength was represented as the failure load, measured in Newtons (N), and defined as the maximal load that could be applied across the suture prior to failure. Each suture was tested dry and after immersion in one of 4 products for 7\u00a0days and tested on day 7. The immersion agents tested were: sodium chloride 0.9%, MicroSafe\u00ae (Sonoma Pharmaceuticals, Petaluma, CA), Aqueous Povidone\u2010iodine 10% solution (Betadine\u2014Mundipharma), and Fucidin ointment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sodium chloride 0.9%, MicroSafe\u00ae, Aqueous Povidone\u2010iodine 10%, and Fucidin seem to increase the failure load of most absorbable and non\u2010absorbable sutures. However, the failure load of Polyglactin 910 suture (Surgilactin, coated, violet\u2010Ethicon) is reduced by long\u2010term exposure to either sodium chloride 0.9% or MicroSafe\u00ae, while the failure load of the Polydioxanone suture (PDS Plus\u2010Ethicon) is reduced by long\u2010term exposure to MicroSafe\u00ae only.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our experiment, the commonly used wound care products have been shown to alter the tensile strength of suture materials. Further human studies are required to ascertain the clinical validity and applicability of our findings.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06788-3","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T21:02:27Z","timestamp":1667250147000},"page":"448-454","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of Topical Agents on the Tensile Strength of Absorbable and Non\u2010absorbable Suture Materials\u2014An in Vitro Study"],"prefix":"10.1002","volume":"47","author":[{"given":"Amar","family":"Alnaqi","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Surgery Kuwait University Kuwait City Kuwait"},{"name":"Department of Pediatric Surgery Ibn Sina Hospital, Sabah Medical Region Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"Burhamah","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad T.","family":"Al\u2010Sultan","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Behavioral Sciences College of Medicine Kuwait University Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esmaeel","family":"Taqi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Ibn Sina Hospital, Sabah Medical Region Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13475"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07039"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0885328210384890"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.5.6.488"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198201001\u201000009"},{"key":"e_1_2_10_7_1","first-page":"44","article-title":"Effect of water temperature on the hydrolysis of two absorbable sutures used in fish surgery","volume":"12","author":"Cannizo SA","year":"2016","journal-title":"Facets"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1906.25210060009002b"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2005.6.377"},{"key":"e_1_2_10_10_1","first-page":"196","article-title":"Wound cleansing: water or saline?","volume":"41","author":"Beam JW","year":"2006","journal-title":"J Athl Train"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2011.03.034"},{"key":"e_1_2_10_12_1","first-page":"473","article-title":"The efficacy and risks of using povidone iodine irrigation to prevent surgical site infection: an evidence\u2010based review","volume":"50","author":"Chundamala J","year":"2007","journal-title":"Can J Surg"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007997709110182"},{"key":"e_1_2_10_14_1","unstructured":"Sonoma pharmaceuticals receives four new UAE regulatory approvals that include acne and antifungal products. 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