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We aim to evaluate analgesic benefits of pectoral nerve (PECS2) block incorporated as part of the enhanced recovery after surgery (ERAS) protocol in patients undergoing mastectomy in University Malaya Medical Centre, Malaysia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A single centre, cohort study evaluating 335 women who have undergone unilateral mastectomy between January 2017 and March 2020\u00a0in Malaysia. Regional anaesthesia were given pre\u2010operatively via ultrasound guided pectoral and intercostal nerves block (PECSII).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Utilization of regional anaesthesia increased from 11% in 2017 to 43% in 2020. Types and duration of surgeries were comparable. Opiod consumption was 3\u00a0mg lower in those who had PECS2 block ((27 [24\u201330] mg), in comparison with those who received general anaesthesia only (30 [26\u201334] mg), <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, and length of stay was half a day shorter in the regional anaesthesia group and these were statistically significant. However, pain score (2 [1\u20133]; 2 [1\u20133], <jats:italic>p<\/jats:italic>=0.719) and post\u2010operative nausea and vomiting (PONV) (32.6\u201332.5%, <jats:italic>p<\/jats:italic>\u2009=\u20090.996) were similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study highlights the importance of PECS2 block as a component of ERAS protocol for mastectomy in an Asian hospital. This study also inferred that patients may be safely discharged within 24 h of surgery and therefore, same day surgery may be feasible in selected group of patients undergoing mastectomy and this could imply overall cost benefits.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-022-06881-7","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T19:02:32Z","timestamp":1672858952000},"page":"564-572","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Benefits of PECS Block as Part of the Enhanced Recovery After Surgery (ERAS) Protocol for Breast Cancer Surgery in an Asian Institution: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"47","author":[{"given":"Kavinya","family":"Diana","sequence":"first","affiliation":[{"name":"Department of Surgery University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8020-3398","authenticated-orcid":false,"given":"Mei\u2010Sze","family":"Teh","sequence":"additional","affiliation":[{"name":"Department of Surgery University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Surgery University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woon\u2010Lai","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Anaestesiology University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi\u2010Yuan","family":"Beh","sequence":"additional","affiliation":[{"name":"Department of Anaestesiology University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nur Aishah Mohd","family":"Taib","sequence":"additional","affiliation":[{"name":"Department of Surgery University Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Organization WH(2020)Cancer. 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