{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T08:31:05Z","timestamp":1709022665520},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to analyze the role of ultrasound\u2010guided vacuum\u2010assisted excision (US\u2010guided VAE) in the treatment of high\u2010risk breast lesions and to evaluate the clinical and US features of the patients associated with recurrence or development of malignancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Between April 2010 and September 2021, 73 lesions of 73 patients underwent US\u2010guided VAE and were diagnosed with high\u2010risk breast lesions. The incidence of recurrence or development of malignancy for high\u2010risk breast lesions was evaluated at follow\u2010up period. The clinical and US features of the patients were analyzed to identify the factors affecting the recurrence or development of malignancy rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only benign phyllodes tumors on US\u2010guided VAE showed recurrences, while other high\u2010risk breast lesions that were atypical ductal hyperplasia (ADH), lobular neoplasia (atypical lobular hyperplasia\/lobular carcinoma in situ), radial scar, and flat epithelial atypia did not show recurrences or malignant transformation. The recurrence rate of the benign phyllodes tumor was 20.8% (5\/24) in a mean follow\u2010up period of 34.3\u00a0months. The recurrence rate of benign phyllodes tumor with distance from nipple of less than 1\u00a0cm was significantly higher than that of lesions with distance from nipple of more than 1\u00a0cm (75% vs. 10%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Benign phyllodes tumors without concurrent breast cancer could be safely followed up instead of surgical excision after US\u2010guided VAE when the lesions were classified as BI\u2010RADS 3 or 4A by US.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-023-06930-9","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T23:16:41Z","timestamp":1675898201000},"page":"1247-1252","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["High\u2010Risk Breast Lesions Diagnosed by Ultrasound\u2010Guided Vacuum\u2010Assisted Excision"],"prefix":"10.1002","volume":"47","author":[{"given":"Ping","family":"He","sequence":"first","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Tao","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of General Surgery Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010Mei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of General Surgery Peking University Third Hospital 100191 Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Peking University Third Hospital 100191 Beijing 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