{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T00:42:17Z","timestamp":1794271337808,"version":"4.9.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Alma Mater Studiorum - Universit\u00e0 di Bologna"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Surgery for thymic cancers is considered the key of curative treatment. Preoperative patients\u2019 characteristics and intraoperative features might influence postoperative outcome. We aim to verify short\u2010term outcomes and possible risk factors for complications after thymectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively investigated patients undergoing surgery for thymoma or thymic carcinoma in the period between January 1, 2008, and December 31, 2021, in our department. Preoperative features, surgical technique (open, bilateral VATS, RATS), intraoperative characteristics and incidence of postoperative complications (PC) were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included in the study 138 patients. Open surgery was performed in 76 patients (55.1%), in 36 VATS (26.1%) and in 26 RATS (36.1%). Resection of one or more adjacent organs due to neoplastic infiltration was required in 25 patients. PC appeared in 25 patients (52% Clavien\u2013Dindo grade I, 12% grade IVa). Open surgery had a higher incidence of PC (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), longer postoperative in\u2010hospital stay (<jats:italic>p<\/jats:italic>\u2009=\u20090.045) and larger neoplasm (<jats:italic>p<\/jats:italic>\u2009=\u20090.006). PC were significant related to pulmonary resection (<jats:italic>p<\/jats:italic>\u2009=\u20090.006), phrenic nerve resection (<jats:italic>p<\/jats:italic>\u2009=\u20090.029), resection of more than one organ (<jats:italic>p<\/jats:italic>\u2009=\u20090.009) and open surgery (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), but only extended surgery of more organs was confirmed as independent prognostic factor for PC (<jats:italic>p<\/jats:italic>\u2009=\u20090.0013). Patients with preoperative myasthenia symptoms have a trend toward stage IVa complications (<jats:italic>p<\/jats:italic>\u2009=\u20090.065). No differences were observed between outcomes of VATS and RATS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Extended resections are related to a higher incidence of PC, while VATS and RATS guarantee a lower incidence of PC and shorter postoperative stay even in patients that require extended resections. Symptomatic myasthenia patients might have a higher risk toward more severe complications.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-023-06996-5","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T19:03:05Z","timestamp":1682017385000},"page":"1978-1985","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Early Postoperative Results after Thymectomy for Thymic Cancer: A Single\u2010Institution Experience"],"prefix":"10.1002","volume":"47","author":[{"given":"Matteo","family":"Petroncini","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiorgio","family":"Solli","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jury","family":"Brandolini","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Antonacci","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Garelli","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kawamukai","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Nicola","family":"Forti Parri","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Bonfanti","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Dolci","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-0099","authenticated-orcid":false,"given":"Pietro","family":"Bertoglio","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Azienda Ospedaliero Universitaria Di Bologna Via Albertoni 15 40138 Bologna Italy"},{"name":"Alma Mater Studiorum Universit\u00e0 di Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2016.01.012"},{"key":"e_1_2_8_3_1","first-page":"299","article-title":"Surgical, radiation, and systemic treatments of patients with thymic epithelial tumours: a clinical practice guideline","volume":"25","author":"Falkson CB","year":"2022","journal-title":"J Thorac 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