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This study aimed to evaluate the clinical characteristics, management strategies, and outcomes of patients with blunt pancreatic injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study was performed on patients with a confirmed blunt pancreatic injury who were admitted to our hospital from March 2008 to December 2020. The clinical characteristics and outcomes of patients receiving different management strategies were compared. The risk factors for in\u2010hospital mortality were evaluated by performing a multivariate regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 98 patients diagnosed with blunt pancreatic injury were identified, with 40 patients having undergone nonoperative treatment (NOT) and 58 patients having undergone surgical treatment (ST). The overall in\u2010hospital deaths were 6 (6.1%), including 2 (5.0%) and 4 (6.9%) in the NOT and ST groups, respectively. Pancreatic pseudocysts occurred in 15 (37.5%) and 3 (5.2%) of the NOT and ST groups, respectively, showing a significant difference between the two groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). In the multivariate regression analysis, concomitant duodenal injury (OR\u2009=\u200914.42, 95% CI 1.27\u2013163.52; <jats:italic>P<\/jats:italic>\u2009=\u20090.031) and sepsis (OR\u2009=\u200943.47, 95% CI, 4.15\u2013455.75; <jats:italic>P<\/jats:italic>\u2009=\u20090.002) were independently associated with in\u2010hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Except for the higher incidence of pancreatic pseudocysts in the NOT group than in the ST group, there were no significant differences in the other clinical outcomes between the two groups. Concomitant duodenal injury and sepsis were the risk factors for in\u2010hospital mortality.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-023-07026-0","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T14:02:30Z","timestamp":1685023350000},"page":"2135-2144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Management and Outcome of Blunt Pancreatic Trauma: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"47","author":[{"given":"Xiaozhi","family":"Lu","sequence":"first","affiliation":[{"name":"Pancreas Center The First Affiliated Hospital of Nanjing Medical University 300 Guangzhou Road 210029 Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Gao","sequence":"additional","affiliation":[{"name":"Pancreas Center The First Affiliated Hospital of Nanjing Medical University 300 Guangzhou Road 210029 Nanjing 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