{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T16:26:54Z","timestamp":1747153614695,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acute appendicitis is one of the most common abdominal emergencies, with management approaches that vary depending on the available resources and setting. However, there is a lack of studies on the differences of surgical outcomes and quality of care between tertiary care hospitals and regional hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter retrospective study included 2158 consecutive adult patients between January 2014 and June 2018 at three hospitals. The patient cohort was divided into regional hospital group (<jats:italic>N<\/jats:italic>\u2009=\u20091223) and tertiary care hospital group (<jats:italic>N<\/jats:italic>\u2009=\u2009935). Baseline characteristics and perioperative outcomes were compared, and factors associated with surgical delay and postoperative complication were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients in tertiary care hospital group had longer surgical waiting time (17.3 vs. 12.0 h, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), higher risks of surgical delay exceeding 24 h (OR\u2009=\u20092.94, 95% CI 2.17\u20134.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), longer operation time (64 vs. 50\u00a0min, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), more appendix perforation (22.4 vs. 13.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and higher hospital cost compared with regional hospital group. In multivariate analysis, factors associated with surgical delay were tertiary care hospital (OR\u2009=\u20092.94, 95% CI 2.18\u20134.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and delay diagnosis (OR\u2009=\u200918.7, 95% CI 11.7\u201330.1, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), while those associated with postoperative complications were older age (OR\u2009=\u20091.02, 95% CI 1.00\u20131.04, <jats:italic>p<\/jats:italic>\u2009=\u20090.013), male sex (OR\u2009=\u20092.38, 95% CI 1.11\u20135.52, <jats:italic>p<\/jats:italic>\u2009=\u20090.031), surgical delay (OR\u2009=\u20092.99, 95% CI 1.30\u20136.47, <jats:italic>p<\/jats:italic>\u2009=\u20090.007), and appendix perforation (OR\u2009=\u20095.61, 95% CI 2.72\u201311.85, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients at tertiary care hospitals had longer waiting time, more surgical delays, and appendix perforations, and these were risk factors of postoperative complications. Establishing an effective referral system to redirect appendicitis patients with less complex medical histories from tertiary care hospitals to regional hospitals may enhance the quality of patient care and outcomes, while also reducing medical costs.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-023-07219-7","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T14:02:35Z","timestamp":1697637755000},"page":"3149-3158","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical Outcomes and Quality of Care Among Adult Appendicitis Patients: A Comparative Study of Tertiary Care Hospitals and Regional Hospitals"],"prefix":"10.1002","volume":"47","author":[{"given":"Ya\u2010Wen","family":"Hsiao","sequence":"first","affiliation":[{"name":"Graduate Institute of Clinical Medicine College of Medicine National Taiwan University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2494-7007","authenticated-orcid":false,"given":"Chih\u2010Yang","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Graduate Institute of Clinical Medicine College of Medicine National Taiwan University Taipei Taiwan"},{"name":"Department of Surgery National Taiwan University Hospital Yun\u2010Lin Branch Yunlin County Taiwan"},{"name":"Department of Surgery National Taiwan University Hospital Hsin\u2010Chu Branch Hsinchu County Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Huang","sequence":"additional","affiliation":[{"name":"Graduate Institute of Clinical Medicine College of Medicine National Taiwan University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng\u2010Sheng","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Traumatology National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po\u2010Yen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgery National Taiwan University Hospital 7 Chung\u2010Shan South Road, Zhongzheng District Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115734"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2014320"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2022.2937"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","unstructured":"SauerlandS JaschinskiT NeugebauerEA. 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