{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:37:24Z","timestamp":1762504644669},"reference-count":0,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,7,19]],"date-time":"2014-07-19T00:00:00Z","timestamp":1405728000000},"content-version":"vor","delay-in-days":5008,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2000,11]]},"abstract":"Abstract<\/jats:title>Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis may also result from a variety of conditions other than thyroid hyperfunction. The present report focuses on the etiologies, pathophysiology, and treatment of iatrogenic<\/jats:italic> thyrotoxicosis. Iatrogenic thyrotoxicosis may be caused by (1) subacute thyroiditis (a result of lymphocytic infiltration, cellular injury, trauma, irradiation) with release of preformed hormones into circulation; (2) excessive ingestion of thyroid hormones (\u201cthyrotoxicosis factitia\u201d); (3) iodine\u2010induced hyperthyroidism (radiologic contrast agents, topical antiseptics, other medications). Among these causes of iatrogenic thyrotoxicosis, that induced by the iodine overload and cytotoxicity associated with amiodarone represents a significant challenge. Successful management of amiodarone\u2010induced thyrotoxicosis requires close cooperation between endocrinologists and endocrine surgeons. Surgical treatment may have a leading yet often underestimated role in view of the potential life\u2010threatening severity of this disease, whereas others kinds of iatrogenic thyrotoxicosis are usually treated conservatively.<\/jats:p>","DOI":"10.1007\/s002680010228","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"1377-1385","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Iatrogenic Thyrotoxicosis: Causal Circumstances, Pathophysiology, and Principles of Treatment\u2014Review of the Literature"],"prefix":"10.1002","volume":"24","author":[{"given":"Michel","family":"Meurisse","sequence":"first","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laragh","family":"Gollogly","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrille","family":"Degauque","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Fumal","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Defechereux","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Hamoir","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery and Transplantation Centre Hospitalier Universitaire de Li\u00e8ge B35, Domaine Universitaire du Sart\u2010Tilman, 4000\u00a0Liege Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,19]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002680010228.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002680010228\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002680010228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T19:32:07Z","timestamp":1703705527000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002680010228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["10.1007\/s002680010228"],"URL":"https:\/\/doi.org\/10.1007\/s002680010228","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}