{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:42:45Z","timestamp":1791070965764,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,4,19]],"date-time":"2014-04-19T00:00:00Z","timestamp":1397865600000},"content-version":"vor","delay-in-days":4887,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2000,12,1]],"date-time":"2000-12-01T00:00:00Z","timestamp":975628800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2000,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to assess the value of lower limb revascularization and free flap transfer (LLR\u2010FFT) in the management of critical leg ischemia and major tissue loss. A total of 29 consecutive patients with critically ischemic leg and major tissue loss underwent 24 simultaneous and 6 staged LLR\u2010FFT procedures. The main outcome measures were bypass graft patency, free flap viability, leg salvage, patients alive with salvaged leg, and survival. At the 2\u2010year follow\u2010up, the bypass graft patency rate was 85%, secondary free flap viability rate was 82%, and 82% of patients achieved leg salvage and were ambulant. If the success was defined as patients being alive with a salvaged leg, the corresponding rate was 80%. Three patients achieved long\u2010term primary patency and leg salvage despite free flap failure, which occurred during the 30\u2010day postoperative period. Lower extremity revascularization plus free flap coverage of large ischemic lesions is valuable in achieving long\u2010term leg salvage. Because revascularization and conventional management of major tissue loss alone can be effective in the management of a small number of cases, staged LLR\u2010FFT is indicated, when appropriate, for better selection of patients undergoing such an aggressive and demanding treatment.<\/jats:p>","DOI":"10.1007\/s002680010273","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"1531-1536","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Lower Limb Revascularization and Free Flap Transfer for Major Ischemic Tissue Loss"],"prefix":"10.1002","volume":"24","author":[{"given":"Erkki","family":"Tukiainen","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery Helsinki University Central Hospital PO Box 266, FIN\u201000029 HUS Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fausto","family":"Biancari","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Meilahti Hospital Helsinki University Central Hospital PO Box 340, FIN\u201000029 HUS, Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauri","family":"Lep\u00e4ntalo","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Meilahti Hospital Helsinki University Central Hospital PO Box 340, FIN\u201000029 HUS, Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,19]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002680010273.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002680010273\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002680010273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T19:33:05Z","timestamp":1705001585000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002680010273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2000,12]]}},"alternative-id":["10.1007\/s002680010273"],"URL":"https:\/\/doi.org\/10.1007\/s002680010273","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,12]]}}}