{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:52:13Z","timestamp":1790182333402,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1996,1,1]],"date-time":"1996-01-01T00:00:00Z","timestamp":820454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A prospective randomized trial comparing laparoscopic appendectomy with open appendectomy in patients with a diagnosis of acute appendicitis was conducted between October 1992 and April 1994. Of the 158 patients randomized, 7 patients were excluded because of protocol violations (conversion to laparotomy in 4, appendix not removed in 3). The 151 patients randomized to either a laparoscopic (<jats:italic>n<\/jats:italic>= 79) or an open appendectomy (<jats:italic>n<\/jats:italic>= 72) showed no difference in sex, age, American Society of Anesthesiology (ASA) rating, or previous abdominal surgery. The histologic classification of normal, catarrhal, inflamed, suppurative, and gangrenous appendicitis was not different between the two groups. Conversion from laparoscopic to open appendectomy was necessary in seven patients (9%) who had advanced forms of appendiceal inflammation. When compared to open appendectomy the laparoscopic group had a longer median operating time (63\u00a0minutes versus 40\u00a0minutes), fewer wound infections (2% versus 11%), less requirement for narcotic analgesia, and an earlier return to normal activity (median 7\u00a0days versus 14\u00a0days). There was no difference in morbidity, and both groups had a median time to discharge of 3\u00a0days. Laparoscopic appendectomy is as safe as open appendectomy; and despite the longer operating time, the advantages such as fewer wound infections and earlier return to normal activity make it a worthwhile alternative for patients with a clinical diagnosis of acute appendicitis.<\/jats:p>","DOI":"10.1007\/s002689900003","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"17-21","source":"Crossref","is-referenced-by-count":152,"title":["Laparoscopic versus Open Appendectomy: Prospective Randomized Trial"],"prefix":"10.1002","volume":"20","author":[{"given":"John Brendan","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Surgery Princess Alexandra Hospital Ipswich Road Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard Mark","family":"Smithers","sequence":"additional","affiliation":[{"name":"Department of Surgery Princess Alexandra Hospital Ipswich Road Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Schache","sequence":"additional","affiliation":[{"name":"Department of Surgery Princess Alexandra Hospital Ipswich Road Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daryl Robert","family":"Wall","sequence":"additional","affiliation":[{"name":"Department of Surgery Princess Alexandra Hospital Ipswich Road Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian John","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Surgery Princess Alexandra Hospital Ipswich Road Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty Lynette","family":"Menzies","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Queensland Brisbane Queensland Australia<!--<country1>AU<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,1]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900003.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900003\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T15:40:39Z","timestamp":1703691639000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1007\/s002689900003"],"URL":"https:\/\/doi.org\/10.1007\/s002689900003","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}