{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:41:07Z","timestamp":1791200467128,"version":"4.2.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1996,1,1]],"date-time":"1996-01-01T00:00:00Z","timestamp":820454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The prospectively collected data from 530 cholecystectomies performed in a university clinic from October 1989 to March 1991 were analyzed after 1 to 3 years of follow\u2010up. The aim of this study was to compare the results of laparoscopic cholecystectomy (LC) for acute cholecystitis with that for routine symptomatic gallbladders. The preoperative, intraoperative, and postoperative parameters of 424 routine (noninflamed) LCs and 54\u00a0LCs for acutely inflamed gallbladders were compared under the \u201cintention to treat\u201d principle. Operating time was longer in the inflamed group (median 97\u00a0minutes versus 75\u00a0minutes; <jats:italic>p<\/jats:italic>&lt; 0.0001). Significantly more adhesions (20% versus 8%), more blood loss (48% versus 19%), a higher incidence of bile spillage (28% versus 12%), and lost stones (19% versus 8%) were encountered in patients with acute cholecystitis. Common bile duct (CBD) injuries were also more frequent in that group (5.5% versus 0.2%;<jats:italic>p<\/jats:italic>= 0.005). The rate of conversion to open surgery was higher than with routine LCs (13% versus 4%). There were two deaths in the routine LC group and none in the acutely inflamed group. There was no difference in postoperative pain intensity or postoperative fatigue according to visual analog scale measurements. Patients with acute cholecystitis stayed only 1\u00a0day longer (median 4\u00a0days versus 3\u00a0days) in hospital. The quality of life scores indicate return to almost normal values by the 14th postoperative day. Long\u2010term follow\u2010up (1\u20133 years) did not reveal any delayed clinical adverse effects. In summary, LC for inflamed gallbladders has a higher conversion rate than LC for routine symptomatic gallbladders. If successfully performed, it has definite benefit for the patient in terms of better postoperative recovery. The trade\u2010off is that the risk of CBD injury is significantly higher.<\/jats:p>","DOI":"10.1007\/s002689900008","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"43-49","source":"Crossref","is-referenced-by-count":139,"title":["Laparoscopic Cholecystectomy for Acute Cholecystitis: Is It Really Safe?"],"prefix":"10.1002","volume":"20","author":[{"given":"Cheng\u2010Kiong","family":"Kum","sequence":"first","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst","family":"Eypasch","sequence":"additional","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Lefering","sequence":"additional","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Paul","sequence":"additional","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund","family":"Neugebauer","sequence":"additional","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Troidl","sequence":"additional","affiliation":[{"name":"Second Department of Surgery University of Cologne, Merheim Surgical Clinic Ostmerheimer Strasse 200 Cologne 51109 Germany<!--<country1>DE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,1]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900008.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900008\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T15:40:52Z","timestamp":1703691652000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1007\/s002689900008"],"URL":"https:\/\/doi.org\/10.1007\/s002689900008","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}