{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T22:53:28Z","timestamp":1775602408883,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The goal of this study was to provide information of prognostic value for gastric endocrine tumors. A total of 205 gastric endocrine tumors have been studied: 193 well differentiated tumors [2 gastrin cell tumors, 191 enterochromaffin\u2010like (ECL) cell tumors] and 12 poorly differentiated carcinomas. Subtyping of ECL cell tumors (carcinoids) resulted in 152 associated with chronic atrophic gastritis (CAG) (type 1); 12 associated with hypertrophic gastropathy (HG) due to Zollinger\u2010Ellison syndrome with multiple endocrine neoplasia type I (type 2), and 27 with no specific association (type 3, sporadic). Type 1 cases occurred most often in female (108 of 152), elderly (mean 63 years) patients, with no tumor\u2010related death at an overall mean follow\u2010up of 53\u00a0months. The 12 type 2 cases were equally distributed between the sexes (six of each), with a mean age of 45 years; there was one tumor\u2010related death (49\u00a0months after diagnosis) and an overall mean survival of 84\u00a0months. Type 3 cases were mostly in men (20 of 27), with a mean age of 55 years; there were seven tumor\u2010related deaths at a mean follow\u2010up of 28\u00a0months. Poorly differentiated neuroendocrine carcinomas were observed in elderly patients (mean 63 years, range 41\u201376 years) of both sexes, with nine tumor\u2010related deaths and a mean survival of 7\u00a0months. It was concluded that correct clinicopathologic subtyping may predict the clinical behavior of gastric endocrine tumors.<\/jats:p>","DOI":"10.1007\/s002689900026","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"168-172","source":"Crossref","is-referenced-by-count":334,"title":["Gastric Carcinoids and Neuroendocrine Carcinomas: Pathogenesis, Pathology, and Behavior"],"prefix":"10.1002","volume":"20","author":[{"given":"Guido","family":"Rindi","sequence":"first","affiliation":[{"name":"Department of Human Pathology and Heredity University of Pavia Via Forlanini 16 27100 Pavia Italy<!--<country1>IT<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Bordi","sequence":"additional","affiliation":[{"name":"Institute of Anatomic Pathology University of Parma Via Gramsci 14 43100 Parma Italy<!--<country1>IT<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigrid","family":"Rappel","sequence":"additional","affiliation":[{"name":"Institute of Pathology Bayreuth Friedrich\u2010Alexander University of Nuremberg Preushwitzer Strasse 101 D\u201095445 Bayreuth Germany<!--<country1>DE<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"La Rosa","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Pavia at Varese Ospedale di Circolo Viale Borri 57 21100 Varese Italy<!--<country1>IT<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Stolte","sequence":"additional","affiliation":[{"name":"Institute of Pathology Bayreuth Friedrich\u2010Alexander University of Nuremberg Preushwitzer Strasse 101 D\u201095445 Bayreuth Germany<!--<country1>DE<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Solcia","sequence":"additional","affiliation":[{"name":"Department of Human Pathology and Heredity University of Pavia Via Forlanini 16 27100 Pavia Italy<!--<country1>IT<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1996,2]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900026.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900026\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T19:47:31Z","timestamp":1705002451000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,2]]}},"alternative-id":["10.1007\/s002689900026"],"URL":"https:\/\/doi.org\/10.1007\/s002689900026","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,2]]}}}