{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T15:48:37Z","timestamp":1792338517546,"version":"4.4.0"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1996,3,1]],"date-time":"1996-03-01T00:00:00Z","timestamp":825638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Surgical treatment for adrenal disease may be withheld from elderly patients because of concern about prohibitive operative morbidity and mortality. To obtain objective data in our practice, we analyzed the results of adrenalectomy for patients aged 65 years and older. From 1984 to 1993 there were 85 patients (41\u00a0men, 44 women) with ages ranging from 65 to 84 years (median 69 years) who underwent adrenalectomy for Cushing syndrome (<jats:italic>n<\/jats:italic>= 19), pheochromocytoma (<jats:italic>n<\/jats:italic>= 16), adrenocortical carcinoma (<jats:italic>n<\/jats:italic>= 7), benign adenoma (<jats:italic>n<\/jats:italic>= 26), or primary hyperaldosteronism (<jats:italic>n<\/jats:italic>= 17) at our institution. Median follow\u2010up was 26\u00a0months (range 1\u00a0month to 9.1 years). A retrospective review with respect to preoperative risks and postoperative morbidity and mortality was performed utilizing the American Society of Anesthesiologists (ASA) physical status classification and the modified Goldman multifactorial cardiac risk scheme. Survival was estimated by the Kaplan\u2010Meier methods. Operative mortality was 7% (six patients). No patients with pheochromocytoma or primary hyperaldosteronism died during the postoperative period. Patients undergoing adrenalectomy for adrenocortical carcinoma had a significantly higher operative mortality (43%) (<jats:italic>p<\/jats:italic>= 0.006). Postoperative complications developed in 19 patients (22%), and there was a reoperation rate of 6% (5 patients). Nineteen percent of patients required postoperative intensive care admission and had a median stay of 2\u00a0days (range, 1\u201338\u00a0days). Median hospital stay was 7\u00a0days (range 3\u201347\u00a0days). Seventy\u2010three patients (86%) remained alive at study completion. Two\u2010 and five\u2010year survivals were 86% and 84%, respectively. Goldman class II or greater was an excellent predictor of increased morbidity (<jats:italic>p<\/jats:italic>= 0.032) and mortality (<jats:italic>p<\/jats:italic>= 0.036). With the exception of adrenocortical carcinoma, adrenal surgery for elderly patients can be performed with acceptable morbidity and mortality. The Goldman multifactorial cardiac risk scheme reliably predicts postoperative outcome in this elderly group of patients.<\/jats:p>","DOI":"10.1007\/s002689900060","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"368-374","source":"Crossref","is-referenced-by-count":17,"title":["Adrenal Surgery in the Elderly: Too Risky?"],"prefix":"10.1002","volume":"20","author":[{"given":"Chung Yau","family":"Lo","sequence":"first","affiliation":[{"name":"Department Surgery Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon A.","family":"van Heerden","sequence":"additional","affiliation":[{"name":"Department Surgery Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clive S.","family":"Grant","sequence":"additional","affiliation":[{"name":"Department Surgery Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon Arne","family":"S\u00f6reide","sequence":"additional","affiliation":[{"name":"Department Surgery Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Warner","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane M.","family":"Ilstrup","sequence":"additional","affiliation":[{"name":"Section of Biostatistics Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,3]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900060.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900060\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T19:47:18Z","timestamp":1705002438000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,3]]}},"alternative-id":["10.1007\/s002689900060"],"URL":"https:\/\/doi.org\/10.1007\/s002689900060","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,3]]}}}