{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:22:07Z","timestamp":1789730527667,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,11]],"date-time":"2014-01-11T00:00:00Z","timestamp":1389398400000},"content-version":"vor","delay-in-days":6433,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To assess the incidence, indications, and complications of (reoperative) thyroid gland surgery in an endemic region, we have retrospectively analyzed 1318 patients operated on between 1983 and 1994. There were 166 reoperations (13.5%). In comparison to the primary operation the indication for reoperation showed an increased rate of premalignant and malignant tumors (+16%) and a decreased rate of hyperthyroid disorders (\u221230%). The largest group operated on had benign multinodular goiters, with the same rate of indication for primary (57.4%) and secondary (57.8%) surgery. Permanent recurrent laryngeal nerve palsy rate following primary operation occurred at rates of 1.7% (1983\u20131990) and 0.7% (1991\u20131994) and for secondary operation 3.5% (1983\u20131990) and 5.6% (1991\u20131994), respectively. The change in recurrent nerve palsy rate in the later years was due to a more extensive resection policy at the primary operation and a more liberal approach to reoperative surgery. The high rate of reoperation for benign goiters (13%) and the new data of goitrogenesis have therefore directed our policy to more extensive resection of the thyroid tissue at the initial operation, increasing the rate of lobectomy from 27% (1982\u20131990) to &gt; 90% (1991\u20131994) and at the same time lowering morbidity. Extensive resection of nodular tissue during the initial operation safely reduces the incidence of recurrent goiter and subsequently reduces the rate of reoperation and eliminates the high risk of morbidity associated with reoperative thyroid surgery. The indications for reoperation should be strict, and when unavoidable a modified lateral approach may be helpful.<\/jats:p>","DOI":"10.1007\/s002689900092","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"593-597","source":"Crossref","is-referenced-by-count":59,"title":["Thyroid Gland Surgery in an Endemic Region"],"prefix":"10.1002","volume":"20","author":[{"given":"Christian A.","family":"Seiler","sequence":"first","affiliation":[{"name":"Department of Visceral and Transplantation Surgery University of Bern Inselspital CH\u20103010 Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Glaser","sequence":"additional","affiliation":[{"name":"Department of Visceral and Transplantation Surgery University of Bern Inselspital CH\u20103010 Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans E.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Visceral and Transplantation Surgery University of Bern Inselspital CH\u20103010 Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,11]]},"reference":[{"key":"e_1_2_1_1_2_1","unstructured":"Bornhauser S.:Zur Geschichte der Schilddr\u00fcsen\u2010 und Kropfforschung im 19: Jahrhundert (unter besonderer Ber\u00fccksichtigung der Schweiz). 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