{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:25:06Z","timestamp":1760099106951},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Serum levels of the carboxy\u2010terminal pyridinoline cross\u2010linked telopeptide of type I collagen (ICTP) and the carboxy\u2010terminal propeptide of type I procollagen (PICP) were measured in 95 patients with renal hyperparathyroidism who had undergone a total parathyroidectomy and autotransplantation of a small portion of the resected gland. The results were compared with the serum levels of other bone metabolic markers and bone mineral densities in the distal radius (R\u2010BMD) and lumbar vertebrae (L\u2010BMD), which were measured by dual energy x\u2010ray absorptiometry and converted to the percentage of the mean value of sex\u2010 and age\u2010matched healthy controls. The preoperative mean values of ICTP and PICP were 142.4\u00a0ng\/ml and 187.8\u00a0ng\/ml, respectively. Although the serum levels of PICP levels exceeded the normal range in 42.1% of the patients, those of ICTP exceeded it in all of them. The serum levels of ICTP correlated positively not only with those of tartrate\u2010resistant acid phosphatase (TRACP), total alkaline phosphatase (ALP), and osteocalcin but also negatively with the values of %R\u2010BMD and %L\u2010BMD and seemed to manifest specifically the disturbance of bone metabolism. On the other hand, the serum levels of PICP correlated with those of ALP and TRACP but not with values of %BMDs. After surgery, the serum levels of ICTP decreased gradually, but those of PICP increased immediately up to peak values at 7\u00a0days and then decreased gradually after 14\u00a0days, reaching the normal range at 3\u00a0months. These changes in the bone metabolic markers seemed to reflect the change in bone metabolism that was converting from bone resorption to bone formation. The percent change in the PICP\/ICTP ratio at 7\u00a0days correlated significantly with the percent change in R\u2010BMD at 12\u00a0months, and it was suggested that postoperative bone gain might be predicted using a combination of postoperative changes in PICP and ICTP.<\/jats:p>","DOI":"10.1007\/s002689900114","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"753-757","source":"Crossref","is-referenced-by-count":10,"title":["Prediction of Bone Mass in Renal Hyperparathyroidism by Newly Developed Bone Metabolic Markers: Evaluation of Serum Levels of Carboxy\u2010Terminal Pyridinoline Cross\u2010Linked Telopeptide of Type I Collagen and Carboxy\u2010Terminal Propeptide of Type I Procollagen"],"prefix":"10.1002","volume":"20","author":[{"given":"Makoto","family":"Katagiri","sequence":"first","affiliation":[{"name":"Department of Surgery Eiju General Hospital 2-11\u20107\u00a0Motoasakusa, Taitouku Tokyo 111 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Fukunaga","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Kawasaki Medical School 577\u00a0Matsushima Kurashiki 701-01 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Ohtawa","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Kawasaki Medical School 577\u00a0Matsushima Kurashiki 701-01 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanekazu","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Kawasaki Medical School 577\u00a0Matsushima Kurashiki 701-01 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1996,7]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900114.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900114\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:12:52Z","timestamp":1704989572000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1007\/s002689900114"],"URL":"https:\/\/doi.org\/10.1007\/s002689900114","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}