{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T02:00:03Z","timestamp":1789524003221,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We review our experience from the surgical management of 57 patients (24\u00a0males, 33 females) with a mean age of 48.5 years who underwent adrenalectomy because of the computed tomography (CT) finding of a \u201cnonfunctioning\u201d adrenal tumor (adrenaloma). We found that CT consistently underestimated the real histologic size of the adrenal tumor (<jats:italic>p<\/jats:italic>= 0.001). Of the 57 resected tumors, 23 were cortical adenomas, 7\u00a0myelolipomas, 8 adrenal cysts, 11\u00a0nodular hyperplasias, 2 primary adenocarcinomas, 2\u00a0metastatic carcinomas, and 4\u00a0pheochromocytomas. The mean diameter was 5.89\u00a0cm and the mean weight 114.07 g. The mean diameter of the resected primary adenocarcinomas was 3.0\u00a0cm and 4.5\u00a0cm, respectively. The operative mortality was zero and the perioperative morbidity minimal. The mean operating time was 137\u00a0minutes (range 60\u2013240\u00a0minutes). The posterior approach had the shortest operating time and the laparoscopic approach the shortest hospital stay and the least postoperative need for narcotics. During the 6.2 years mean follow\u2010up period, five patients with preoperative hypertension remained normotensive, and both patients with the resected primary adenocarcinomas are alive without recurrence. We suggest a more liberal surgical approach to patients with adrenalomas because: (1) even small tumors can be malignant or potentially lethal (e.g., pheochromocytomas); (2) some tumors that appear to be nonfunctioning may in reality be functioning; and (3) other nonfunctioning tumors may, with time (and without prior notice), function. The low risk of adrenalectomy especially via the laparoscopic approach can provide an early definitive diagnosis and treatment, avoiding the cost of repeated CT scans and other studies as suggested by the currently prevailing conservative management of these tumors.<\/jats:p>","DOI":"10.1007\/s002689900120","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"788-793","source":"Crossref","is-referenced-by-count":53,"title":["Adrenaloma: A Call for More Aggressive Management"],"prefix":"10.1002","volume":"20","author":[{"given":"Dimitrios A.","family":"Linos","sequence":"first","affiliation":[{"name":"Department of Surgery Athens Medical School Mikras Asias 75, Goudi Athens 115 27 Greece<!--<country1>GR<\/country1>-->"},{"name":"Third Surgical Clinic Department of Surgery Hygeia Hospital Kifissias Avenue and Erythrou Stravrou 4, Marousi Athens 151 23 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Stylopoulos","sequence":"additional","affiliation":[{"name":"Department of Surgery Athens Medical School Mikras Asias 75, Goudi Athens 115 27 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotirios A.","family":"Raptis","sequence":"additional","affiliation":[{"name":"Ipsilantou 45-47 Evangelismos Hospital Athens 115 10 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,7]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900120\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:12:24Z","timestamp":1704989544000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1007\/s002689900120"],"URL":"https:\/\/doi.org\/10.1007\/s002689900120","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}