{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:03:43Z","timestamp":1783487023622,"version":"3.55.0"},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Eighty\u2010two children and adolescents (18\u00a0males, 64 females; median age 14 years) surgically treated for Graves\u2019 disease at a single institution between 1979 and 1993 were retrospectively reviewed. Most of the patients (74%) coming to thyroidectomy had been treated medically for a period ranging from 2 to 80 (median 15) months. Bilateral subtotal thyroid resection was the most frequently performed procedure (86%). Postoperatively, no permanent recurrent laryngeal nerve palsy or permanent hypocalcemia occurred. Operative mortality was zero. With a median follow\u2010up of 8.3 years, recurrent hyperthyroidism occurred in five patients (6%), one of whom required reoperation. Most children and adolescents with Graves\u2019 disease can be rendered euthyroid by nonsurgical treatment options. However, prolonged and ineffective medical treatment should be avoided in these patients who are in the formative years of their lives. Surgical treatment, when indicated and employed, offers young patients with Graves\u2019 disease a safe, rapid, definitive, cost\u2010effective treatment with a high success rate.<\/jats:p>","DOI":"10.1007\/s002689900121","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"794-800","source":"Crossref","is-referenced-by-count":22,"title":["Surgical Treatment of Graves\u2019 Disease in Patients Younger than 18 Years"],"prefix":"10.1002","volume":"20","author":[{"given":"Jon\u2010Arne","family":"S\u00f6reide","sequence":"first","affiliation":[{"name":"Department of Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon A.","family":"van Heerden","sequence":"additional","affiliation":[{"name":"Department of Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Yau","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clive S.","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adolescent Medicine Mayo Clinic 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane M.","family":"Ilstrup","sequence":"additional","affiliation":[{"name":"Section of Biostatistics Mayo Clinic and Mayo Foundation 200 First Street SW Rochester Minnesota 55905 U.S.A.<!--<country1>US<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,7]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900121\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:12:25Z","timestamp":1704989545000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1007\/s002689900121"],"URL":"https:\/\/doi.org\/10.1007\/s002689900121","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}