{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:01:07Z","timestamp":1705017667900},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1997,3,1]],"date-time":"1997-03-01T00:00:00Z","timestamp":857174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1997,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>During the last decades a number of left ventricular assist devices has been used especially for patients resistant to pharmacologic treatment and to intraaortic balloon pump (IABP) support for left ventricular failure. A high stroke volume para\u2010aortic counterpulsation device (PACD) has been developed utilizing the principle of the diastolic counterpulsation technique. In this study the hemodynamic effects of the valveless PACD were compared to those of the centrifugal blood pump (CBP) in nine dogs in acute experimental cardiogenic shock. Hemodynamic measurements were obtained at baseline with both devices off, PACD on and CBP off, or PACD off and CBP on. There was no difference in mean aortic pressure between PACD on (60.0 \u00b1 11.5\u00a0mmHg) and CBP on (69.0 \u00b1 26.8\u00a0mmHg). Similarly, there was no difference in left ventricular end\u2010diastolic pressure with the PACD on (11.9 \u00b1 5.4\u00a0mmHg) versus the CBP on (9.9 \u00b1 5.2\u00a0mmHg) or the cardiac index with the PACD on (84 \u00b1 36\u00a0ml\/kg\/min) versus the CBP on (77 \u00b1 36\u00a0ml\/kg\/min). However, the left ventricular systolic pressure (55.0 \u00b1 19.0 with PACD versus 73.0 \u00b1 26.0 with CBP,<jats:italic>p<\/jats:italic>&lt; 0.001), the tension time index (712 \u00b1 381 versus 1333 \u00b1 694,<jats:italic>p<\/jats:italic>&lt; 0.01), and the double product (5629 \u00b1 2574 versus 7440 \u00b1 3294,<jats:italic>p<\/jats:italic>&lt; 0.01) were significantly lower during assistance with the PACD than with the CBP. It was concluded that PACD is at least as effective as CBP for restoring hemodynamic status during acute experimental cardiogenic shock. Moreover, the PACD unloads the left ventricle more effectively than CBP, making it suitable for left ventricular mechanical support in cases with reversible myocardial damage.<\/jats:p>","DOI":"10.1007\/s002689900236","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"318-322","source":"Crossref","is-referenced-by-count":2,"title":["High Stroke Volume Para\u2010aortic Counterpulsation Device versus Centrifugal Pump in Cardiogenic Shock: Experimental Study"],"prefix":"10.1002","volume":"21","author":[{"given":"Serafim N.","family":"Nanas","sequence":"first","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John N.","family":"Nanas","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos E.","family":"Charitos","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandros","family":"Gougoulakis","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Makaritsis","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Chatzigeorgiou","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiriaki","family":"Moussoutzani","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria I.","family":"Anastasiou\u2010Nana","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spyridon D.","family":"Moulopoulos","sequence":"additional","affiliation":[{"name":"Department of Clinical Therapeutics National and Kapodistrian University of Athens Vas. Sofias 80 &amp; K. Lourou Athens 11518 Greece<!--<country1>GR<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1997,3]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900236.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900236\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:01:05Z","timestamp":1704988865000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["10.1007\/s002689900236"],"URL":"https:\/\/doi.org\/10.1007\/s002689900236","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}