{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:59:20Z","timestamp":1783983560053,"version":"3.55.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1998,4,1]],"date-time":"1998-04-01T00:00:00Z","timestamp":891388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1998,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary aldosteronism consists of a mixture of subgroups. The operative treatment is successful only in cases of aldosterone\u2010producing neoplasia (and in rare cases of primary unilateral hyperplasia); all other cases should be treated medically. The aim of this study was to determine if aldosterone\u2010producing neoplasia had been successfully differentiated from the other subgroups and the outcome of operative treatment. Altogether 29 patients with primary aldosteronism were operated on between January 1, 1979 and December 31, 1993. Patient charts were reviewed retrospectively. The follow\u2010up data were collected from the patients\u2019 charts, and all patients were contacted to obtain recent blood pressure and serum potassium values. The patients were asked about symptoms related to hyperaldosteronism. If any suspicion of recidive aldosteronism was present, patients were carefully reexamined by hormonal tests and computed tomography (CT). A total of 27 patients had unilateral adenoma, 1 patient had hyperplasia, and 1 patient had an aldosterone\u2010producing cortical carcinoma. There was no operative mortality or morbidity. The serum potassium level had normalized in all patients. Mean follow\u2010up time was 76\u00a0months. One patient died during the follow\u2010up from cholangiocarcinoma; 11 patients (41%) were cured by the operation, 10 patients (37%) have a mild but medicated hypertension, and in the remaining 22% the hypertension persisted but was well controlled by the medication. Of the 29 patients, 28 were correctly diagnosed as having an aldosterone\u2010producing neoplasm. Basic hormonal studies and CT can be used effectively to differentiate aldosterone\u2010producing neoplasia from hyperplasia in most cases.<\/jats:p>","DOI":"10.1007\/s002689900407","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"418-422","source":"Crossref","is-referenced-by-count":21,"title":["Adrenalectomy for Primary Aldosteronism: Long\u2010term Follow\u2010up Study in 29\u00a0Patients"],"prefix":"10.1002","volume":"22","author":[{"given":"Jukka","family":"Sir\u00e9n","sequence":"first","affiliation":[{"name":"Department of Surgery Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"V\u00e4lim\u00e4ki","sequence":"additional","affiliation":[{"name":"Department of Medicine Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kauko","family":"Huikuri","sequence":"additional","affiliation":[{"name":"Department of Surgery Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arto","family":"Sivula","sequence":"additional","affiliation":[{"name":"Department of Surgery Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petri","family":"Voutilainen","sequence":"additional","affiliation":[{"name":"Department of Surgery Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reijo","family":"Haapiainen","sequence":"additional","affiliation":[{"name":"Department of Surgery Helsinki University Central Hospital Haartmaninkatu 4 SF\u201000290 Helsinki Finland<!--<country1>FI<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1998,4]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900407\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:53:21Z","timestamp":1704992001000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1998,4]]}},"alternative-id":["10.1007\/s002689900407"],"URL":"https:\/\/doi.org\/10.1007\/s002689900407","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,4]]}}}