{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:29:32Z","timestamp":1761154172857},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1998,6]]},"abstract":"Abstract<\/jats:title>The success of parathyroid surgery is determined by the identification and removal of all parathyroid tumors. Parathyroid tumors accumulate and retain 2\u2010methoxyisobutylisonitrile (MIBI) labeled with technetium\u201099m. Intravenous injection of this radiopharmacon prior to parathyroid surgery allows identification of parathyroid tumors with a hand\u2010held gamma detector. To assess the value of this technique, a case\u2013control study was performed with 62 patient having nuclear\u2010guided parathyroidectomy and 60 patients having conventional parathyroid explorations. The sensitivity rates of the MIBI probe in single and multiple gland disease were 84.6% and 63.0%, respectively. Rates of success, temporary and permanent hypoparathyroidism, and injury of the recurrent laryngeal nerve were similar in patients who underwent probe\u2010guided surgery and those who had conventional surgery. In conclusion, although the MIBI probe appears to be a valuable tool in parathyroid surgery, its use has not improved the outcome of such surgery at our institution.<\/jats:p>","DOI":"10.1007\/s002689900427","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"507-512","source":"Crossref","is-referenced-by-count":23,"title":["2\u2010Methoxyisobutylisonitrile Probe during Parathyroid Surgery: Tool or Gadget?"],"prefix":"10.1002","volume":"22","author":[{"given":"H. Jaap","family":"Bonjer","sequence":"first","affiliation":[{"name":"Department of Surgery University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajo A.","family":"Bruining","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huib A.P.","family":"Pols","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wouter W.","family":"de Herder","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles A.G.","family":"Proye","sequence":"additional","affiliation":[{"name":"Department of Surgery Hopital C. Huriez University Hospital Place der Verdun, Metro C.H.R., Oscar Lambret 59037 Lille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno M.L.","family":"Carnaille","sequence":"additional","affiliation":[{"name":"Department of Surgery Hopital C. Huriez University Hospital Place der Verdun, Metro C.H.R., Oscar Lambret 59037 Lille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.A.","family":"Mohammedamin","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewout W.","family":"Steyerberg","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus University Postbus 1738 3000 DR Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wout A.P.","family":"Breeman","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik P.","family":"Krenning","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine University Hospital Dijkzigt Dr. Molenwaterplein 40 3015 GD Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1998,6]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689900427.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689900427\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689900427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:51:17Z","timestamp":1704991877000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689900427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1007\/s002689900427"],"URL":"https:\/\/doi.org\/10.1007\/s002689900427","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}