{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T09:59:33Z","timestamp":1707904773580},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T00:00:00Z","timestamp":1392336000000},"content-version":"vor","delay-in-days":5158,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pancreaticogastrostomy (PG) has been reintroduced and employed occasionally as a useful alternative to pancreaticojejunostomy (PJ) after Whipple resection or pylorus\u2010preserving pancreaticoduodenectomy (PPPD). Although the physiologic alteration in the stomach is important for the correlation between gastric and pancreatic functions, the actual intragastric pH profile after PG is still unclear. This study was conducted to investigate the physiologic changes in gastric pH and serum gastrin and secretin levels before and after PPPD reconstructed with PG (PPPD\u2010PG) in humans. Twenty\u2010four hour continuous intragastric pH and serum gastrin and secretin levels in the fasting state were examined in 25 patients who had undergone PPPD\u2010PG. No peptic ulcer was detected after the operation. After PG, serum gastrin and secretin levels were unchanged. Twenty\u2010four hour gastric pH monitoring revealed two distinct patterns during the nocturnal period before the operation: patients with acid\u2010type secretion (<jats:italic>n<\/jats:italic>= 11) exhibited a persistent acid pH, whereas those with alkaline\u2010type secretion (<jats:italic>n<\/jats:italic>= 14) had cyclic variations between an acid and an alkaline pH value. After PG, in both acid\u2010 and alkaline\u2010type patients, median pH and percentages of time that the gastric pH was less than 4 (% pH &lt; 4) and more than 6 (% pH &gt; 6) did not change, and circadian pH patterns also remained unchanged. These results suggest that PPPD\u2010PG has little influence on gastric acidity, and the neurohumoral relation between the stomach, duodenum, and pancreas is preserved after PG. Therefore, physiologically, PG can be recommended as a reconstructive procedure after PPPD.<\/jats:p>","DOI":"10.1007\/s002689910016","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T05:57:49Z","timestamp":1030255069000},"page":"86-91","source":"Crossref","is-referenced-by-count":12,"title":["Gastric Acidity following Pancreaticogastrostomy with Pylorus\u2010preserving Pancreaticoduodenectomy"],"prefix":"10.1002","volume":"24","author":[{"given":"Hiroyuki","family":"Shinchi","sequence":"first","affiliation":[{"name":"First Department of Surgery Kagoshima University School of Medicine 8\u201035\u20101, Sakuragaoka, Kagoshima 890\u20108520 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonshin","family":"Takao","sequence":"additional","affiliation":[{"name":"First Department of Surgery Kagoshima University School of Medicine 8\u201035\u20101, Sakuragaoka, Kagoshima 890\u20108520 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeho","family":"Maenohara","sequence":"additional","affiliation":[{"name":"First Department of Surgery Kagoshima University School of Medicine 8\u201035\u20101, Sakuragaoka, Kagoshima 890\u20108520 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Aikou","sequence":"additional","affiliation":[{"name":"First Department of Surgery Kagoshima University School of Medicine 8\u201035\u20101, Sakuragaoka, Kagoshima 890\u20108520 Japan<!--<country1>JP<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,14]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s002689910016.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s002689910016\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s002689910016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T17:01:55Z","timestamp":1703696515000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s002689910016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1007\/s002689910016"],"URL":"https:\/\/doi.org\/10.1007\/s002689910016","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}