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Patient (atherosclerotic risk factors, comorbidities, medications), vessel (elongation), lesion (stenosis grade, length, calcification, location), and stent characteristics (material, diameter, length, fracture) were examined. Duplex ultrasonography was used to monitor stent patency. The Mann\u2013Whitney <jats:italic>U<\/jats:italic> and Fisher\u2019s exact tests, Kaplan\u2013Meier analyses, and a log-rank test were used statistically.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The median follow-up time was 35\u00a0months (interquartile range, 20\u2013102\u00a0months). Significant (\u2265\u200970%) ISR developed in 14 patients (27.5%; stenosis, <jats:italic>N<\/jats:italic>\u2009=\u200910; entire CCA occlusion, <jats:italic>N<\/jats:italic>\u2009=\u20094). Primary patency rates were 98%, 92%, 83%, 73%, and 61% at 6, 12, 24, 60, and 96\u00a0months, respectively. Reintervention was performed in six patients (11.8%) with nonocclusive ISR. Secondary patency rates were 100% at 6 and 12\u00a0months and 96% at 24, 60, and 96\u00a0months. In-stent restenosis developed more frequently (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) in patients with hyperlipidemia; primary patency rates were also significantly worse (Chi-square, 11.08; degrees of freedom, 1; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) in patients with hyperlipidemia compared to those without.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Stenting of the middle\/distal CCA can be performed with acceptable patency rates. If intervention is unequivocally needed, patients with hyperlipidemia will require closer follow-up care.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Level of Evidence<\/jats:title>\n<jats:p>Level 3, Local non-random sample.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00270-020-02522-5","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T20:02:11Z","timestamp":1590091331000},"page":"1134-1142","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Middle and Distal Common Carotid Artery Stenting: Long-Term Patency Rates and Risk Factors for In-Stent Restenosis"],"prefix":"10.1007","volume":"43","author":[{"given":"Mikl\u00f3s","family":"V\u00e9rtes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dat T.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Sz\u00e9kely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1kos","family":"B\u00e9rczi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edit","family":"D\u00f3sa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"2522_CR1","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/B978-0-323-29544-4.00022-0","volume-title":"Stroke: pathophysiology, diagnosis, and management","author":"LH Bonati","year":"2016","unstructured":"Bonati LH, Brown MM. 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The study protocol has obtained Institutional Review Board approval from the Semmelweis University Regional and Institutional Committee of Science and Research Ethics (Approval No. 174\/2018).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Informed consent was obtained from all individual participants who had fluoroscopy for evaluation of stent fracture.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}