{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:08:51Z","timestamp":1773857331086,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"C. R. Bard, a wholly owned subsidiary of Becton, Dickinson and Company"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Intervent Radiol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>This study aimed to assess the safety, effectiveness, and feasibility of the Liverty\u2122 transjugular intrahepatic portosystemic shunt (TIPS) access set, which has an ergonomic handle that allows for <jats:italic>in situ<\/jats:italic> cannula tip deflection and a distal steerable cannula angle, <jats:italic>versus<\/jats:italic> the COOK\u00ae Rosch-Uchida Transjugular Liver Access Set (RUPS-100) in healthy pigs.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Twelve pigs randomly underwent TIPS with the Liverty\u2122 set or the RUPS-100 set. Three interventionalists performed 4 TIPS procedures, 2 with each set. The primary outcome was procedural success, defined as successful establishment of the intrahepatic portosystemic shunt and stent placement.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The shunt was successfully established in 11 pigs. The procedural success was achieved in all 6 pigs in the Liverty\u2122 group and 5 out of 6 pigs for the RUPS-100 group (Fisher exact test, <jats:italic>P<\/jats:italic>\u2009&gt;\u20090.999). The mean duration of puncture was shorter in the Liverty\u2122 group <jats:italic>versus<\/jats:italic> the RUPS-100 group (12.3\u2009\u00b1\u20094.5\u00a0min <jats:italic>vs.<\/jats:italic> 16.2\u2009\u00b1\u20098.5\u00a0min), but without significant statistical difference (two sample<jats:italic> t<\/jats:italic> test, <jats:italic>P<\/jats:italic>\u2009=\u20090.359). The cannula angle was adjusted 69% of passes in the Liverty\u2122 group, which was significantly higher than that in the RUPS-100 group (12%, <jats:italic>P<\/jats:italic>\u2009=\u20090.004). Overall, the TIPS procedural performance was comparable between the groups. Both sets were safe. No intraabdominal hemorrhage, vascular injuries, tissue or organ injuries, porto-biliary fistula, biliary peritonitis, and infection or abscess occurred in either group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The Liverty\u2122 set is safe and has similar procedural metrics to the COOK\u00ae RUPS-100 set. It allows <jats:italic>in situ<\/jats:italic> adjustment of the angle of the stiffening cannula without increasing procedure time and lessens the occurrences of periprocedural complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00270-023-03544-5","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T18:02:03Z","timestamp":1695060123000},"page":"1394-1400","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Safety and Effectiveness of a Novel Tips Access Set with Steerable Cannula in a Swine Model"],"prefix":"10.1007","volume":"46","author":[{"given":"PengXu","family":"Ding","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijie","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangqiang","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzheng","family":"Zhuge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"issue":"4","key":"3544_CR1","doi-asserted-by":"publisher","first-page":"634","DOI":"10.2214\/ajr.22.27626","volume":"219","author":"S Dastmalchian","year":"2022","unstructured":"Dastmalchian S, Aryafar H, Tavri S. Intravascular ultrasound guidance for tips procedures: a review. AJR Am J Roentgenol. 2022;219(4):634\u201346. https:\/\/doi.org\/10.2214\/ajr.22.27626.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"3544_CR2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1053\/j.tvir.2016.01.002","volume":"19","author":"K Farsad","year":"2016","unstructured":"Farsad K, Kaufman JA. Novel image guidance techniques for portal vein targeting during transjugular intrahepatic portosystemic shunt creation. Tech Vasc Interv Radiol. 2016;19(1):10\u201320. https:\/\/doi.org\/10.1053\/j.tvir.2016.01.002.","journal-title":"Tech Vasc Interv Radiol"},{"issue":"2","key":"3544_CR3","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1055\/s-0043-1768609","volume":"40","author":"JL Herren","year":"2023","unstructured":"Herren JL, Shah KY, Patel M, Niemeyer MM. Intravascular ultrasound for transjugular intrahepatic portosystemic shunt creation: \u201cTIPS\u201d and Tricks. Semin Intervent Radiol. 2023;40(2):212\u201320. https:\/\/doi.org\/10.1055\/s-0043-1768609.","journal-title":"Semin Intervent Radiol"},{"issue":"8","key":"3544_CR4","doi-asserted-by":"publisher","first-page":"3215","DOI":"10.1007\/s00330-018-5316-3","volume":"28","author":"X Luo","year":"2018","unstructured":"Luo X, Wang X, Yu J, Zhu Y, Xi X, Ma H, et al. Transjugular intrahepatic portosystemic shunt creation: three-dimensional roadmap versus CO(2) wedged hepatic venography. Eur Radiol. 2018;28(8):3215\u201320. https:\/\/doi.org\/10.1007\/s00330-018-5316-3.","journal-title":"Eur Radiol"},{"issue":"1","key":"3544_CR5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1055\/s-0043-1767688","volume":"40","author":"I Sinha","year":"2023","unstructured":"Sinha I, Goldman DT, Patel RS, Nowakowski FS. Advanced techniques for accessing the portal vein during transjugular intrahepatic portosystemic shunt creation. Semin Intervent Radiol. 2023;40(1):79\u201386. https:\/\/doi.org\/10.1055\/s-0043-1767688.","journal-title":"Semin Intervent Radiol"},{"key":"3544_CR6","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2021-000815","author":"S Partovi","year":"2021","unstructured":"Partovi S, Li X, Shwaiki O, Rashwan B, Ruff C, Grozinger G, et al. Advanced portal venous access techniques for transjugular intrahepatic portosystemic shunt placement. BMJ Open Gastroenterol. 2021. https:\/\/doi.org\/10.1136\/bmjgast-2021-000815.","journal-title":"BMJ Open Gastroenterol"},{"key":"3544_CR7","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jss.2019.12.038","volume":"250","author":"E Lada","year":"2020","unstructured":"Lada E, Anna M, Patrik M, Zbynek T, Miroslav J, Hynek M, et al. Porcine liver anatomy applied to biomedicine. 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Harborsite preclinical laboratory, certified by AAALAC (certification number: 001821), is a third party service institution in China for the animal studies in the field of medical devices. It has established a corresponding quality system according to the regulatory requirements of FDA GLP, which can meet the requirements of FDA, CE and NMPA for the registration of animal studies. All applicable international, national, and\/or institutional guidelines for the care and use of animals were followed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"All applicable international, national, and\/or institutional guidelines for the care and use of animals were followed.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"For this type of study, consent for publication is not required.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}