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This study compares the first clinically available photon-counting detector CT to third-generation dual-source energy-integrating detector CT.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and Methods<\/jats:title>\n                <jats:p>Nylon cylinders with central bores (4\u00a0mm, 2\u00a0mm), mimicking 75% and 95% stenoses, were placed inside seven different 8-mm diameter stents and filled with diluted contrast medium. Phantoms were scanned with photon-counting detector CT at slice thicknesses of 0.2\u00a0mm (available only in this scanner type), 0.5\u00a0mm, and 1.0\u00a0mm versus 0.5\u00a0mm and 1.0\u00a0mm in energy-integrating detector CT at matched CT dose indices. Contrast-to-noise ratios were calculated from attenuation rates. Residual lumen size was measured as full width at half-maximum. Subjective image quality was assessed by two independent blinded raters.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Mean contrast-to-noise ratio was lowest in photon-counting detector CT at 0.2\u00a0mm slice thickness (0%, 75%, and 95% in-stent restenosis: 6.11\u2009\u00b1\u20090.6, 5.27\u2009\u00b1\u20090.54, and 5.02\u2009\u00b1\u20090.66) and highest at 1.0\u00a0mm slice thicknesses with similar measurements in photon-counting detector CT and energy-integrating detector CT (11.46\u2009\u00b1\u20091.08, 9.94\u2009\u00b1\u20091.01, 8.26\u2009\u00b1\u20091.0 vs. 3.34\u2009\u00b1\u20091.0, 9.92\u2009\u00b1\u20090.38, 7.94\u2009\u00b1\u20091.07). Mean full width at half-maximum measurements in photon-counting detector CT at 0.2\u00a0mm slice thickness for 0%, 75%, and 95% in-stent restenosis were 8.00\u2009\u00b1\u20090.37, 3.98\u2009\u00b1\u20090.34, and 1.92\u2009\u00b1\u20090.16\u00a0mm. Full width at half-maximum was least precise in 95% in-stent restenosis at 1.0\u00a0mm slice thickness with similar measurements between scanners (1.57\u2009\u00b1\u20090.33 vs. 1.71\u2009\u00b1\u20090.15\u00a0mm). Interrater correlation coefficient was 0.75 [95% CI: [0.53; 0.86]; subjective scores were best at 0.2\u00a0mm slice thickness in photon-counting detector CT (19.43\u2009\u00b1\u20090.51 and 19.00\u2009\u00b1\u20090.68).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In phantom in-stent restenosis in 8\u00a0mm stents, we observed similar full width at half-maximum for photon-counting detector CT and energy-integrating detector CT in 0% and 75% in-stent restenosis, but at 95% in-stent restenosis, FWHM tended to be more accurate in smaller slice thicknesses in both scanners. Subjective image assessment yielded best results at 0.2\u00a0mm slice thickness in photon-counting detector CT despite lower contrast-to-noise ratio.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00270-024-03874-y","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T21:15:00Z","timestamp":1730841300000},"page":"65-74","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["In-Stent Restenosis in Peripheral Arterial Disease: Ultra-High-Resolution Photon-Counting Versus Third-Generation Dual-Source Energy-Integrating Detector CT Phantom Study in Seven Different Stent Types"],"prefix":"10.1007","volume":"48","author":[{"given":"Theresa-Marie","family":"Dachs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven R.","family":"Hauck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Kern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina","family":"Klausenitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Hoffner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Schernthaner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanaa","family":"Abdel-Rahman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Hannover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Strassl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Loewe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7300-1288","authenticated-orcid":false,"given":"Martin A.","family":"Funovics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"3874_CR1","unstructured":"Siemens Healthineers launches world\u2019s first CT scanner with photon-counting technology. 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