{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:29:24Z","timestamp":1789144164520,"version":"build-2803163510"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Cukurova University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Intervent Radiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>To investigate the influence of sarcopenia on the outcomes of endovascular treatment in patients with pelvic venous insufficiency (PVI).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Material and Methods<\/jats:title>\n            <jats:p>A retrospective analysis was conducted on 62 female patients who underwent endovascular treatment for PVI between January 2012 and July 2020. The patients were evaluated using the Visual Analog Scale (VAS) for chronic pelvic pain, both before treatment and three months post-treatment. A successful treatment outcome was defined as a reduction in pelvic pain by 50% or more. Sarcopenia was diagnosed based on the skeletal muscle mass index (SMI) of the patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Sarcopenia was present in 20 (32.3%) patients. There was no significant difference in preprocedural VAS scores between sarcopenic and non-sarcopenic patients (36.2\u2009\u00b1\u200916.9 vs. 34.9\u2009\u00b1\u200916.1, <jats:italic>p<\/jats:italic>\u2009=\u20090.781). However, non-sarcopenic patients achieved a significantly greater reduction in VAS scores post-treatment (67.6\u2009\u00b1\u200922.4% vs. 53.1\u2009\u00b1\u200924.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.025). A moderate negative correlation was observed between sarcopenia and successful treatment outcomes (<jats:italic>r<\/jats:italic>\u2009=\u2009-0.365, <jats:italic>p<\/jats:italic>\u2009=\u20090.004).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Sarcopenia negatively impacts the effectiveness of endovascular treatment in patients with PVI.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Graphical Abstract<\/jats:title>\n          <\/jats:sec>","DOI":"10.1007\/s00270-025-04051-5","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T13:01:04Z","timestamp":1748005264000},"page":"992-999","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Sarcopenia on Outcomes Following Endovascular Treatment of Patients with Pelvic Venous Insufficiency"],"prefix":"10.1007","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3626-2312","authenticated-orcid":false,"given":"Sinan","family":"Sozutok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4092-1077","authenticated-orcid":false,"given":"Ferhat Can","family":"Piskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7998-0686","authenticated-orcid":false,"given":"Omer","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1486-2782","authenticated-orcid":false,"given":"Hasan Bilen","family":"Onan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5324-0097","authenticated-orcid":false,"given":"Huseyin Tugsan","family":"Balli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8423-3949","authenticated-orcid":false,"given":"Erol Huseyin","family":"Aksungur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,23]]},"reference":[{"issue":"341","key":"4051_CR1","doi-asserted-by":"publisher","first-page":"4834","DOI":"10.1136\/bmj.c4834","volume":"5","author":"JP Daniels","year":"2010","unstructured":"Daniels JP, Khan KS. Chronic pelvic pain in women. BMJ. 2010;5(341):4834.","journal-title":"BMJ"},{"issue":"3","key":"4051_CR2","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.jvsv.2020.12.084","volume":"9","author":"MH Meissner","year":"2021","unstructured":"Meissner MH, Khilnani NM, Labropoulos N, et al. The symptoms-varices-pathophysiology classification of pelvic venous disorders: a report of the american vein & lymphatic society international working group on pelvic venous disorders. J Vasc Surg Venous Lymphat Disord. 2021;9(3):568\u201384.","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"12","key":"4051_CR3","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1007\/s00270-024-03782-1","volume":"47","author":"NM Khilnani","year":"2024","unstructured":"Khilnani NM, Xia JJ, Winokur RS, Meissner MH. Diagnosis and management of pelvic venous disorders in women. Cardiovasc Intervent Radiol. 2024;47(12):1650\u201368.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"5","key":"4051_CR4","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1177\/0268355521999559","volume":"36","author":"MH Meissner","year":"2021","unstructured":"Meissner MH, Khilnani NM, Labropoulos N, Gasparis AP, Gibson K, Greiner M, et al. The symptoms-varices-pathophysiology classification of pelvic venous disorders: a report of the american vein & lymphatic society international working group on pelvic venous disorders. Phlebology. 2021;36(5):342\u201360.","journal-title":"Phlebology"},{"issue":"1","key":"4051_CR5","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s42155-023-00365-y","volume":"6","author":"E Kashef","year":"2023","unstructured":"Kashef E, Evans E, Patel N, Agrawal D, Hemingway AP. Pelvic venous congestion syndrome: female venous congestive syndromes and endovascular treatment options. CVIR Endovasc. 2023;6(1):25.","journal-title":"CVIR Endovasc"},{"key":"4051_CR6","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1148\/radiology.216.2.r00au22440","volume":"216","author":"RD Harris","year":"2000","unstructured":"Harris RD, Holtzman SR, Poppe AM. Clinical outcome in female patients with pelvic pain and normal pelvic US findings. Radiology. 2000;216:440\u20133.","journal-title":"Radiology"},{"key":"4051_CR7","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.ijgo.2012.04.021","volume":"118","author":"CJM van der Vleuten","year":"2012","unstructured":"van der Vleuten CJM, van Kempen JAL, Schultze-Kool LJ. Embolization to treat pelvic congestion syndrome and vulval varicose veins. Int J Gynaecol Obstet. 2012;118:227\u201330.","journal-title":"Int J Gynaecol Obstet"},{"issue":"3","key":"4051_CR8","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jbspin.2018.08.001","volume":"86","author":"A Tournadre","year":"2019","unstructured":"Tournadre A, Vial G, Capel F, Soubrier M, Boirie Y. Sarcopenia. Joint Bone Spine. 2019;86(3):309\u201314.","journal-title":"Joint Bone Spine"},{"key":"4051_CR9","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s40200-017-0302-x","volume":"16","author":"G Shafiee","year":"2017","unstructured":"Shafiee G, Keshtkar A, Soltani A, Ahadi Z, Larijani B, Heshmat R. Prevalence of sarcopenia in the world: a systematic review and meta-analysis of general population studies. J Diabetes Metab Disord. 2017;16:21.","journal-title":"J Diabetes Metab Disord."},{"issue":"5","key":"4051_CR10","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s00270-024-03676-2","volume":"47","author":"PJW Arntz","year":"2024","unstructured":"Arntz PJW, Olthof PB, Korenblik R, et al. Effect of sarcopenia on the increase in liver volume and function after portal vein embolization. Cardiovasc Intervent Radiol. 2024;47(5):642\u20139.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4051_CR11","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1093\/ageing\/afq034","volume":"39","author":"AJ Cruz-Jentoft","year":"2010","unstructured":"Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. European working group on sarcopenia in older people. sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing. 2010;39:412\u201323.","journal-title":"Age Ageing"},{"issue":"1","key":"4051_CR12","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s00270-021-02961-8","volume":"45","author":"W Cai","year":"2022","unstructured":"Cai W, Lin H, Qi R, et al. Psoas muscle density predicts occurrences of hepatic encephalopathy in patients receiving transjugular intrahepatic portosystemic shunts within 1 year. Cardiovasc Intervent Radiol. 2022;45(1):93\u2013101.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4051_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1034\/j.1600-0838.2003.00298.x","volume":"13","author":"T Rantanen","year":"2003","unstructured":"Rantanen T. Muscle strength, disability and mortality: Strengths and disablement. Scand J Med Sci Sports. 2003;13:3\u20138.","journal-title":"Scand J Med Sci Sports"},{"key":"4051_CR14","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s13539-014-0161-y","volume":"5","author":"JE Morley","year":"2014","unstructured":"Morley JE, Anker SD, von Haehling S. Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014. J Cachexia Sarcopenia Muscle. 2014;5:253\u20139.","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"4051_CR15","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1093\/oxfordjournals.aje.a009520","volume":"14","author":"RN Baumgartner","year":"1998","unstructured":"Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, et al. Epidemiology of sarcopenia among the elderly in new Mexico. Am J Epidemiol. 1998;14:755\u201363.","journal-title":"Am J Epidemiol"},{"issue":"1","key":"4051_CR16","doi-asserted-by":"publisher","first-page":"11369","DOI":"10.1038\/s41598-018-29825-5","volume":"8","author":"BA Derstine","year":"2018","unstructured":"Derstine BA, Holcombe SA, Ross BE, Wang NC, Su GL, Wang SC. Skeletal muscle cutoff values for sarcopenia diagnosis using T10 to L5 measurements in a healthy US population. Sci Rep. 2018;8(1):11369.","journal-title":"Sci Rep"},{"issue":"6","key":"4051_CR17","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1136\/rapm-2022-104097","volume":"48","author":"H Shanthanna","year":"2023","unstructured":"Shanthanna H, Eldabe S, Provenzano DA, Bouche B, Buchser E, Chadwick R, et al. Evidence-based consensus guidelines on patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain. Reg Anesth Pain Med. 2023;48(6):273\u201387.","journal-title":"Reg Anesth Pain Med"},{"key":"4051_CR18","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1055\/s-0040-1713912","volume":"42","author":"JBD Silva","year":"2020","unstructured":"Silva JBD, Gurian MBF, Nonino CB, Poli-Neto OB, Nogueira AA, Reis FJCD, et al. Analysis of body composition and pain intensity in women with chronic pelvic pain secondary to endometriosis. Rev Bras Ginecol Obstet. 2020;42:486\u201392.","journal-title":"Rev Bras Ginecol Obstet"},{"key":"4051_CR19","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.urology.2006.02.005","volume":"68","author":"ME Nielsen","year":"2006","unstructured":"Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392\u20136.","journal-title":"Urology"},{"key":"4051_CR20","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1002\/nau.20069","volume":"23","author":"M Morin","year":"2004","unstructured":"Morin M, Bourbonnais D, Gravel D, Dumoulin C, Lemieux M-C. Pelvic floor muscle function in continent and stress urinary incontinent women using dynamometric measurements. Neurourol Urodyn. 2004;23:668\u201374.","journal-title":"Neurourol Urodyn"},{"key":"4051_CR21","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1586\/eog.12.13","volume":"7","author":"MBF Gurian","year":"2012","unstructured":"Gurian MBF, de Souza AM, da Silva APM, et al. Chronic pelvic pain of musculoskeletal cause in women. Exp Rev Obstetrics Gynecol. 2012;7:149\u201357.","journal-title":"Exp Rev Obstetrics Gynecol"},{"key":"4051_CR22","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1097\/00003081-200312000-00006","volume":"46","author":"SA Prendergast","year":"2003","unstructured":"Prendergast SA, Weiss JM. Screening for Musculoskeletal Causes of Pelvic Pain. Clin Obstet Gynecol. 2003;46:773\u201382.","journal-title":"Clin Obstet Gynecol"},{"key":"4051_CR23","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1007\/s10350-006-0814-9","volume":"50","author":"S Heymen","year":"2007","unstructured":"Heymen S, Scarlett Y, Jones K, Ringel Y, Drossman D, Whitehead WE. Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. Dis Colon Rectum. 2007;50:428\u201341.","journal-title":"Dis Colon Rectum"},{"key":"4051_CR24","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s00192-004-1256-3","volume":"16","author":"JL Amaro","year":"2005","unstructured":"Amaro JL, Moreira ECH, Gameiro MO, Padovani CR. Pelvic floor muscle evaluation in incontinent patients. Int Urogynecol J. 2005;16:352\u20134.","journal-title":"Int Urogynecol J"},{"key":"4051_CR25","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1111\/j.1365-2753.2009.01202.x","volume":"16","author":"MLL De Souza Montenegro","year":"2010","unstructured":"De Souza Montenegro MLL, Mateus-Vasconcelos EC, Candido dos Reis FJ. Thiele massage as a therapeutic option for women with chronic pelvic pain caused by tenderness of pelvic floor muscles: Thiele massage and chronic pelvic pain. J Eval Clin Pract. 2010;16:981\u20132.","journal-title":"J Eval Clin Pract."},{"key":"4051_CR26","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.ejogrb.2021.06.037","volume":"263","author":"RRL Silva","year":"2021","unstructured":"Silva RRL, Coutinho JFV, Vasconcelos CTM, et al. Prevalence of sarcopenia in older women with pelvic floor dysfunction. Eur J Obstet Gynecol Reprod Biol. 2021;263:159\u201363.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"4051_CR27","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-024-03823-9","author":"V Risner","year":"2024","unstructured":"Risner V, Gonzales E, McColgan Y, Salazar G. Interventional radiology treatments to address chronic pelvic pain in females. Cardiovasc Intervent Radiol. 2024. https:\/\/doi.org\/10.1007\/s00270-024-03823-9","journal-title":"Cardiovasc Intervent Radiol."},{"issue":"6","key":"4051_CR28","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1007\/s00270-024-03731-y","volume":"47","author":"M Szmygin","year":"2024","unstructured":"Szmygin M, Pyra K, B\u00e8rczi V, Wo\u017aniak S, \u015awiat\u0142owski \u0141, Paszkowski T. Endovascular treatment of pelvic venous congestion syndrome in nulliparous patients-preliminary results of 10 years of experience. Cardiovasc Intervent Radiol. 2024;47(6):822\u2013828. https:\/\/doi.org\/10.1007\/s00270-024-03731-y","journal-title":"Cardiovasc Intervent Radiol."}],"container-title":["CardioVascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-025-04051-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00270-025-04051-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-025-04051-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T15:20:15Z","timestamp":1757172015000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00270-025-04051-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,23]]},"references-count":28,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["4051"],"URL":"https:\/\/doi.org\/10.1007\/s00270-025-04051-5","relation":{},"ISSN":["1432-086X"],"issn-type":[{"value":"1432-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,23]]},"assertion":[{"value":"11 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethics committee approval was obtained from \u00c7ukurova University Faculty of Medicine Clinical Research Ethics Committee dated 5 November 2021 and numbered 116.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"The study was retrospective from previous imaging studies of the patients and verbal informed consent was obtained.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}