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New therapeutic options have been developed to manage both benign and malignant conditions refractory to medical treatments or for which surgery has failed or is not feasible, particularly regarding locally advanced liver tumours, vascular malformations and vascular tumours of the liver, lymphatic disorders, portal hypertension and complications of liver transplantation. A multidisciplinary approach is essential for the optimal management of patients, as well as for increasing the awareness of paediatricians and surgeons regarding IR. 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