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The survey assessed symptom response to UFE, need for additional procedures, and patient satisfaction with UFE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>976 women underwent UFE; of these, 173 were younger than 40 at the time of UFE, and 80 of 173 (46.2%) participated in the survey. Median age at embolization was 37.2 (range 26.4\u201339.8) and when surveyed was 52.7 (range 43.1\u201361.9). 70.0% (56\/80) and 18.8% (15\/80) of patients reported \u201ca lot\u201d or \u201ca little\u201d symptom improvement, respectively, in the first 6\u00a0months after UFE; 11.2% (9\/80) reported no change. Of those with improvement, symptoms returned in 57.7% (41\/71) with median time to recurrence of 11.0\u00a0years (range 0.5\u201320\u00a0years). Freedom from recurrence of symptoms was 68\/71 (95.8%) at 1\u00a0year, 48\/71 (67.6%) at 5\u00a0years, and 36\/71 (50.7%) at 10\u00a0years. Freedom from hysterectomy for recurrent symptoms was 70\/71 (98.6%) at 1\u00a0year, 60\/71 (84.5%) at 5\u00a0years, and 51\/71 (71.8%) at 10\u00a0years. Patient satisfaction with having UFE was a median of 5 on a scale of 1\u20135 (5\u2009=\u2009very satisfied).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Women under 40 who undergo UFE are likely to experience return of symptoms before menopause and may require additional procedures, yet they remain highly satisfied with the procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level 4, Case Series<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00270-026-04402-w","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T18:59:49Z","timestamp":1774637989000},"page":"1391-1399","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Long-Term Outcomes of Uterine Artery Embolization for Treatment of Fibroids in Women Under 40: A Retrospective Survey Study at Two Institutions with Median 16-year Follow-up"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6937-157X","authenticated-orcid":false,"given":"Elisabeth R.","family":"Seyferth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil E.","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D.","family":"Shlansky-Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"issue":"4","key":"4402_CR1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.ajog.2013.07.017","volume":"209","author":"BJ Borah","year":"2013","unstructured":"Borah BJ, Nicholson WK, Bradley L, Stewart EA. 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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study has obtained IRB approval from the Hospital of the University of Pennsylvania Institutional Review Board and the need for informed consent was waived. For this type of study, consent for publication is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}