{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T20:08:55Z","timestamp":1788725335773,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Intervent Radiol"],"DOI":"10.1007\/s00270-026-04588-z","type":"journal-article","created":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T19:25:32Z","timestamp":1788722732000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preoperative CT-Guided Cryoneurolysis of the Genicular Nerves Before Total Knee Arthroplasty: Study Protocol for a Prospective Randomized Controlled Trial"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1140-548X","authenticated-orcid":false,"given":"Vasileios","family":"Balomenos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ornella","family":"Moschovaki-Zeiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Koulouvaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Savvidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Mastrokalos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Kelekis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Fillipiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Koulalis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,6]]},"reference":[{"issue":"5","key":"4588_CR1","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1016\/j.arth.2020.11.013","volume":"36","author":"WM Mihalko","year":"2021","unstructured":"Mihalko WM, Kerkhof AL, Ford MC, Crockarell JR, Harkess JW, Guyton JL. Cryoneurolysis before total knee arthroplasty in patients with severe osteoarthritis for reduction of postoperative pain and opioid use in a single-center randomized controlled trial. J Arthroplasty. 2021;36(5):1590\u20138.","journal-title":"J Arthroplasty"},{"issue":"1","key":"4588_CR2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2011-000435","volume":"2","author":"AD Beswick","year":"2012","unstructured":"Beswick AD, Wylde V, Gooberman-Hill R, Blom A, Dieppe P. What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients. BMJ Open. 2012;2(1):e000435.","journal-title":"BMJ Open"},{"issue":"9","key":"4588_CR3","volume":"12","author":"BE Lung","year":"2022","unstructured":"Lung BE, Karasavvidis T, Sharma AK, Amirhekmat A, Stepanyan H, McMaster W, et al. Cryoneurolysis is a safe, effective modality to improve rehabilitation after total knee arthroplasty. Life (Basel). 2022;12(9):1344.","journal-title":"Life (Basel)"},{"issue":"5","key":"4588_CR4","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.diii.2020.11.007","volume":"102","author":"D Filippiadis","year":"2021","unstructured":"Filippiadis D, Efthymiou E, Tsochatzis A, Kelekis A, Prologo JD. Percutaneous cryoanalgesia for pain palliation: current status and future trends. Diagn Interv Imaging. 2021;102(5):273\u20138.","journal-title":"Diagn Interv Imaging"},{"issue":"3","key":"4588_CR5","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.knee.2016.01.011","volume":"23","author":"V Dasa","year":"2016","unstructured":"Dasa V, Lensing G, Ali M, Deen J, Avelar R. Percutaneous freezing of sensory nerves prior to total knee arthroplasty. Knee. 2016;23(3):523\u20138.","journal-title":"Knee"},{"key":"4588_CR6","first-page":"E125","volume":"27","author":"A Stogicza","year":"2024","unstructured":"Stogicza A. Genicular nerve ultrasound-guided cryoanalgesia for the treatment of chronic knee joint pain: an observational retrospective study. Pain Physician. 2024;27:E125\u201332.","journal-title":"Pain Physician"},{"key":"4588_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-8-148","volume":"8","author":"H Kapstad","year":"2010","unstructured":"Kapstad H, Rokne B, Stavem K. Psychometric properties of the Brief Pain Inventory among patients with osteoarthritis undergoing total hip replacement surgery. Health Qual Life Outcomes. 2010;8:148.","journal-title":"Health Qual Life Outcomes"},{"issue":"3","key":"4588_CR8","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1526-4637.2009.00774.x","volume":"11","author":"TM Atkinson","year":"2010","unstructured":"Atkinson TM, Mendoza TR, Sit L, Passik S, Scher HI, Cleeland C, et al. The Brief Pain Inventory and its \u201cPain at its worst in the last 24 hours\u201d item: clinical trial endpoint considerations. Pain Med. 2010;11(3):337\u201346.","journal-title":"Pain Med"},{"issue":"2","key":"4588_CR9","first-page":"129","volume":"23","author":"CS Cleeland","year":"1994","unstructured":"Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994;23(2):129\u201338.","journal-title":"Ann Acad Med Singapore"},{"issue":"8","key":"4588_CR10","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1016\/j.joca.2016.03.010","volume":"24","author":"NJ Collins","year":"2016","unstructured":"Collins NJ, Prinsen CA, Christensen R, Bartels EM, Terwee CB, Roos EM. Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta-analysis of measurement properties. Osteoarthritis Cartilage. 2016;24(8):1317\u201329.","journal-title":"Osteoarthritis Cartilage"},{"key":"4588_CR11","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/1477-7525-1-64","volume":"1","author":"EM Roos","year":"2003","unstructured":"Roos EM, Lohmander LS. Knee injury and Osteoarthritis Outcome Score (KOOS)\u2014a review of its psychometric properties. Health Qual Life Outcomes. 2003;1:64.","journal-title":"Health Qual Life Outcomes"},{"issue":"12","key":"4588_CR12","first-page":"1833","volume":"15","author":"N Bellamy","year":"1988","unstructured":"Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15(12):1833\u201340.","journal-title":"J Rheumatol"},{"key":"4588_CR13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1477-7525-2-45","volume":"2","author":"S McConnell","year":"2004","unstructured":"McConnell S, Kolopack P, Davis AM. The WOMAC health status index: a review of its psychometric properties. Health Qual Life Outcomes. 2004;2:45.","journal-title":"Health Qual Life Outcomes"},{"issue":"1","key":"4588_CR14","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/00012272-198510000-00005","volume":"8","author":"CE Ferrans","year":"1985","unstructured":"Ferrans CE, Powers MJ. Quality of Life Index: development and psychometric properties. Adv Nurs Sci. 1985;8(1):15\u201324.","journal-title":"Adv Nurs Sci"},{"issue":"1","key":"4588_CR15","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s00270-025-04200-w","volume":"49","author":"D Filippiadis","year":"2026","unstructured":"Filippiadis D, Pereira PL, Hausegger KA, Ryan AG, Binkert CA. CIRSE standards of practice for the classification of complications: the modified CIRSE classification system. Cardiovasc Intervent Radiol. 2026;49(1):2\u20136.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"6","key":"4588_CR16","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1097\/j.pain.0000000000000516","volume":"157","author":"J Goesling","year":"2016","unstructured":"Goesling J, Moser SE, Zaidi B, et al. Trends and predictors of opioid use after total knee and total hip arthroplasty. Pain. 2016;157(6):1259\u201365.","journal-title":"Pain"},{"issue":"8","key":"4588_CR17","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1136\/rapm-2021-103304","volume":"47","author":"S Hinds","year":"2022","unstructured":"Hinds S, Miller J, Maccani M, et al. Patient risk screening to improve transitions of care in surgical opioid prescribing. Reg Anesth Pain Med. 2022;47(8):475\u201383.","journal-title":"Reg Anesth Pain Med"},{"issue":"4","key":"4588_CR18","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1016\/j.arth.2019.08.036","volume":"35","author":"KC Roberts","year":"2020","unstructured":"Roberts KC, Moser SE, Collins AC, et al. Prescribing and consumption of opioids after primary, unilateral total hip and knee arthroplasty in opioid-naive patients. J Arthroplasty. 2020;35(4):960\u20135.","journal-title":"J Arthroplasty"}],"container-title":["CardioVascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-026-04588-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00270-026-04588-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-026-04588-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T19:25:33Z","timestamp":1788722733000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00270-026-04588-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,6]]},"references-count":18,"alternative-id":["4588"],"URL":"https:\/\/doi.org\/10.1007\/s00270-026-04588-z","relation":{},"ISSN":["1432-086X"],"issn-type":[{"value":"1432-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,6]]},"assertion":[{"value":"3 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Approved by the Ethics Committee and Institutional Review Board of the National and Kapodistrian University of Athens (Approval ID: A9, 10\/09\/2025).","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Consent for publication will be obtained for every individual person\u2019s data included in the study.","order":3,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent will be obtained from all individual participants included in the study.","order":4,"name":"Ethics","label":"Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}