{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T20:26:31Z","timestamp":1793651191895,"version":"4.5.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100000398","name":"Royal College of Radiologists","doi-asserted-by":"publisher","award":["Pump Prime"],"award-info":[{"award-number":["Pump Prime"]}],"id":[{"id":"10.13039\/501100000398","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Intervent Radiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To quantify the resource use and procedural costs attributable to transcatheter CT hepatic angiography during single-room computed tomography-guided microwave ablation of liver tumours.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A prospective bottom-up micro-costing analysis was conducted from the UK National Health Service perspective. Resource utilisation data were collected from 35 consecutive patients undergoing hepatic angiography-assisted microwave ablation in a single-room equipped with a standard computed tomography scanner and a mobile C-arm. Unit costs were identified using National Health Service reference costs and the Personal Social Services Research Unit databases. Per-procedure costs incorporated staff time, equipment and consumables, and imaging-related capital costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median costs were \u00a34,499 (\u00a32,361\u20138,001) for the ablation component and \u00a31,142 (\u00a3929\u20131,584) for hepatic angiography, with a median combined procedure cost, calculated independently, of \u00a35,689 (\u00a33,533\u20139,296). The hepatic angiography component was equivalent to 25.4% of the median ablation-component cost. Among the sensitivity scenarios tested, angiography duration had the greatest influence on its incremental cost, producing estimates of \u00a3929\u20131,584.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hepatic angiography adds a measurable incremental cost to computed tomography-guided microwave ablation. These results provide a foundation for prospective studies evaluating whether improved intraprocedural assessment translates into reduced re-intervention and improved cost-effectiveness.<\/jats:p>\n                    <jats:p>\n                      <jats:italic>Level of Evidence<\/jats:italic>\n                      : Level 4, case series.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00270-026-04640-y","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:37:13Z","timestamp":1791401833000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Procedural Micro-Costing of Single-Room Transcatheter CT Hepatic Angiography for Microwave Liver Ablation"],"prefix":"10.1007","author":[{"given":"Emma C.","family":"Dunne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"Navato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Mathiszig-Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicos","family":"Fotiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward W.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"4640_CR1","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S1470-2045(24)00660-0","volume":"26","author":"S van der Lei","year":"2025","unstructured":"van der Lei S, Puijk R, Dijkstra M, et al. Thermal ablation versus surgical resection of small-size colorectal liver metastases (COLLISION): an international, randomised, controlled, phase 3 non-inferiority trial. Lancet Oncol. 2025;26:187\u201399. https:\/\/doi.org\/10.1016\/S1470-2045(24)00660-0.","journal-title":"Lancet Oncol"},{"key":"4640_CR2","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.jvir.2014.02.008","volume":"25","author":"AAJM van Tilborg","year":"2014","unstructured":"van Tilborg AAJM, Scheffer HJ, Nielsen K, van Waesberghe JHTM, Comans EF, van Kuijk C, et al. Transcatheter CT arterial portography and CT hepatic arteriography for liver tumor visualization during percutaneous ablation. 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Margin size is an independent predictor of local tumor progression after ablation of colon cancer liver metastases. Cardiovasc Intervent Radiol. 2013;36:166\u201375. https:\/\/doi.org\/10.1007\/s00270-012-0377-1.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4640_CR5","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s00270-025-04273-7","volume":"49","author":"S van der Lei","year":"2026","unstructured":"van der Lei S, Santangelo D, Balasupramaniam K, Tubbing D, Dijkstra M, Puijk RS, et al. Intratumoural contrast tagging during CT hepatic arteriography-guided microwave ablation of colorectal liver metastases (t-CTHA) to enhance tumour targeting and margin assessment. Cardiovasc Intervent Radiol. 2026;49:527\u201336. https:\/\/doi.org\/10.1007\/s00270-025-04273-7.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"1173","key":"4640_CR6","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1093\/bjr\/tqaf117","volume":"98","author":"EW Johnston","year":"2025","unstructured":"Johnston EW, Basso J, Farooq S, McDonagh E, Giansante L, Cunningham D, Koh DM, Meijerink M, Fotiadis N. Single-room transcatheter CT hepatic angiography for microwave liver ablation: a feasibility and safety study. Br J Radiol. 2025;98(1173):1394\u2013402. https:\/\/doi.org\/10.1093\/bjr\/tqaf117.","journal-title":"Br J Radiol"},{"key":"4640_CR7","unstructured":"NHS England. National Cost Collection for the NHS. Available at: https:\/\/www.england.nhs.uk\/costing-in-the-nhs\/national-cost-collection\/. 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Abdom Radiol. 2022;47:1457\u201363. https:\/\/doi.org\/10.1007\/s00261-022-03463-y.","journal-title":"Abdom Radiol"},{"key":"4640_CR13","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1007\/s00270-023-03545-4","volume":"46","author":"MLJ Smits","year":"2023","unstructured":"Smits MLJ, Bruijnen RCG, Tetteroo P, Vonken EJPA, Meijerink MR, Hagendoorn J, et al. Hepatic arteriography and C-Arm CT-guided ablation (HepACAGA) to improve tumor visualization, navigation and margin confirmation in percutaneous liver tumor ablation. Cardiovasc Intervent Radiol. 2023;46:1365\u201374. https:\/\/doi.org\/10.1007\/s00270-023-03545-4.","journal-title":"Cardiovasc Intervent Radiol"}],"container-title":["CardioVascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-026-04640-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00270-026-04640-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00270-026-04640-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:41:26Z","timestamp":1793648486000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00270-026-04640-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,7]]},"references-count":13,"alternative-id":["4640"],"URL":"https:\/\/doi.org\/10.1007\/s00270-026-04640-y","relation":{},"ISSN":["1432-086X"],"issn-type":[{"value":"1432-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,7]]},"assertion":[{"value":"20 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 October 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"\u201cBLINDED\u201d deleted in four in-text citations: three on PDF page 2 and one on page 3.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"EW Johnston has received a once-off consultancy fee from Philips related to CT hepatic angiography. All other authors declare no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the institutional service evaluation committee, identifier SE1361.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For this type of study formal consent is not required.","order":3,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For this type of study formal consent is not required.","order":4,"name":"Ethics","label":"Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}