{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:00:37Z","timestamp":1790096437459,"version":"4.0.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Radiol Anat"],"DOI":"10.1007\/s00276-024-03409-7","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T18:05:22Z","timestamp":1718301922000},"page":"1331-1344","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Frontal trans opercular approaches to the insula: building the mental picture from procedure-guided anatomical dissection"],"prefix":"10.1007","volume":"46","author":[{"given":"Salvatore","family":"Marino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2822-0035","authenticated-orcid":false,"given":"Guillaume","family":"Dannhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5348-8052","authenticated-orcid":false,"given":"Christophe","family":"Destrieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6037-0407","authenticated-orcid":false,"given":"Igor Lima","family":"Maldonado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"3409_CR1","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1177\/00031348211048845","volume":"89","author":"MJ Asken","year":"2023","unstructured":"Asken MJ, Hortian VA, Elder C, Yang HC (2023) SIM: the surgery imagery mindset and preparing for surgery. Am Surg 89:948\u2013951. https:\/\/doi.org\/10.1177\/00031348211048845","journal-title":"Am Surg"},{"key":"3409_CR2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.3171\/2014.12.JNS142182","volume":"124","author":"A Benet","year":"2016","unstructured":"Benet A, Hervey-Jumper SL, S\u00e1nchez JJG, Lawton MT, Berger MS (2016) Surgical assessment of the insula. Part 1: surgical anatomy and morphometric analysis of the transsylvian and transcortical approaches to the insula. J Neurosurg 124:469\u2013481. https:\/\/doi.org\/10.3171\/2014.12.JNS142182","journal-title":"J Neurosurg"},{"key":"3409_CR3","doi-asserted-by":"publisher","DOI":"10.23736\/S0390-5616.21.05344-3","author":"E Burkhardt","year":"2022","unstructured":"Burkhardt E, Kinoshita M, Herbet G (2022) Functional anatomy of the frontal aslant tract and surgical perspectives. J Neurosurg Sci. https:\/\/doi.org\/10.23736\/S0390-5616.21.05344-3","journal-title":"J Neurosurg Sci"},{"key":"3409_CR4","doi-asserted-by":"publisher","first-page":"2559","DOI":"10.1200\/JCO.2011.38.4818","volume":"30","author":"PC De Witt Hamer","year":"2012","unstructured":"De Witt Hamer PC, Robles SG, Zwinderman AH, Duffau H, Berger MS (2012) Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J Clin Oncol 30:2559\u20132565. https:\/\/doi.org\/10.1200\/JCO.2011.38.4818","journal-title":"J Clin Oncol"},{"key":"3409_CR5","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1007\/s00701-014-2167-9","volume":"156","author":"M Delion","year":"2014","unstructured":"Delion M, Mercier P (2014) Microanatomical study of the insular perforating arteries. Acta Neurochir (Wien) 156:1991\u20131998. https:\/\/doi.org\/10.1007\/s00701-014-2167-9","journal-title":"Acta Neurochir (Wien)"},{"key":"3409_CR6","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1159\/000464393","volume":"30","author":"H Duffau","year":"2018","unstructured":"Duffau H (2018) Surgery of insular gliomas. Prog Neurol Surg 30:173\u2013185. https:\/\/doi.org\/10.1159\/000464393","journal-title":"Prog Neurol Surg"},{"key":"3409_CR7","doi-asserted-by":"publisher","first-page":"2622","DOI":"10.1002\/cncr.20297","volume":"100","author":"H Duffau","year":"2004","unstructured":"Duffau H, Capelle L (2004) Preferential brain locations of low-grade gliomas. Cancer 100:2622\u20132626. https:\/\/doi.org\/10.1002\/cncr.20297","journal-title":"Cancer"},{"key":"3409_CR8","doi-asserted-by":"publisher","first-page":"764","DOI":"10.3171\/jns.2003.98.4.0764","volume":"98","author":"H Duffau","year":"2003","unstructured":"Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Taillandier L, Lopes M, Mitchell M-C, Roche S, Muller J-C, Bitar A, Sichez J-P, van Effenterre R (2003) Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neurosurg 98:764\u2013778. https:\/\/doi.org\/10.3171\/jns.2003.98.4.0764","journal-title":"J Neurosurg"},{"key":"3409_CR9","doi-asserted-by":"publisher","first-page":"E7","DOI":"10.3171\/2009.5.FOCUS0938","volume":"27","author":"H Duffau","year":"2009","unstructured":"Duffau H, Moritz-Gasser S, Gatignol P (2009) Functional outcome after language mapping for insular World Health Organization Grade II gliomas in the dominant hemisphere: experience with 24 patients. Neurosurg Focus 27:E7. https:\/\/doi.org\/10.3171\/2009.5.FOCUS0938","journal-title":"Neurosurg Focus"},{"key":"3409_CR10","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1007\/s10143-021-01602-5","volume":"45","author":"TA Dziedzic","year":"2022","unstructured":"Dziedzic TA, Bala A, Marchel A (2022) Anatomical aspects of the insula, opercula and peri-insular white matter for a transcortical approach to insular glioma resection. Neurosurg Rev 45:793\u2013806. https:\/\/doi.org\/10.1007\/s10143-021-01602-5","journal-title":"Neurosurg Rev"},{"key":"3409_CR11","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.3171\/2014.10.JNS14945","volume":"122","author":"M Fujii","year":"2015","unstructured":"Fujii M, Maesawa S, Motomura K, Futamura M, Hayashi Y, Koba I, Wakabayashi T (2015) Intraoperative subcortical mapping of a language-associated deep frontal tract connecting the superior frontal gyrus to Broca\u2019s area in the dominant hemisphere of patients with glioma. J Neurosurg 122:1390\u20131396. https:\/\/doi.org\/10.3171\/2014.10.JNS14945","journal-title":"J Neurosurg"},{"key":"3409_CR12","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3171\/2018.10.JNS181519","volume":"130","author":"SL Hervey-Jumper","year":"2019","unstructured":"Hervey-Jumper SL, Berger MS (2019) Insular glioma surgery: an evolution of thought and practice: JNSPG 75th anniversary invited review article. J Neurosurg 130:9\u201316. https:\/\/doi.org\/10.3171\/2018.10.JNS181519","journal-title":"J Neurosurg"},{"key":"3409_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.906466","volume":"9","author":"GR Isolan","year":"2022","unstructured":"Isolan GR, Buffon V, Maldonado I, Monteiro JM, Ya\u011fmurlu K, Ribas CAPM, Roesler R, Malafaia O (2022) Avoiding vascular complications in insular glioma surgery\u2014a microsurgical anatomy study and critical reflections regarding intraoperative findings. Front Surg 9:906466. https:\/\/doi.org\/10.3389\/fsurg.2022.906466","journal-title":"Front Surg"},{"key":"3409_CR14","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.bandl.2008.11.005","volume":"109","author":"SS Keller","year":"2009","unstructured":"Keller SS, Crow T, Foundas A, Amunts K, Roberts N (2009) Broca\u2019s area: Nomenclature, anatomy, typology and asymmetry. Brain Lang 109:29\u201348. https:\/\/doi.org\/10.1016\/j.bandl.2008.11.005","journal-title":"Brain Lang"},{"key":"3409_CR15","first-page":"247","volume":"36","author":"J Klingler","year":"1935","unstructured":"Klingler J (1935) Erleichterung der makroskopischen Praeparation des Gehirns durch den Gefrierprozess. Schweiz Arch Neurol Psychiatr 36:247\u2013256","journal-title":"Schweiz Arch Neurol Psychiatr"},{"key":"3409_CR16","doi-asserted-by":"publisher","first-page":"450","DOI":"10.3171\/2015.3.JNS142680","volume":"124","author":"C Koutsarnakis","year":"2016","unstructured":"Koutsarnakis C, Liakos F, Liouta E, Themistoklis K, Sakas D, Stranjalis G (2016) The cerebral isthmus: fiber tract anatomy, functional significance, and surgical considerations. J Neurosurg 124:450\u2013462. https:\/\/doi.org\/10.3171\/2015.3.JNS142680","journal-title":"J Neurosurg"},{"key":"3409_CR17","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.641586","volume":"12","author":"E La Corte","year":"2021","unstructured":"La Corte E, Eldahaby D, Greco E, Aquino D, Bertolini G, Levi V, Ottenhausen M, Demichelis G, Romito LM, Acerbi F, Broggi M, Schiariti MP, Ferroli P, Bruzzone MG, Serrao G (2021) The frontal aslant tract: a systematic review for neurosurgical applications. Front Neurol 12:641586. https:\/\/doi.org\/10.3389\/fneur.2021.641586","journal-title":"Front Neurol"},{"key":"3409_CR18","doi-asserted-by":"publisher","first-page":"638","DOI":"10.3171\/jns.2001.95.4.0638","volume":"95","author":"FF Lang","year":"2001","unstructured":"Lang FF, Olansen NE, DeMonte F, Gokaslan ZL, Holland EC, Kalhorn C, Sawaya R (2001) Surgical resection of intrinsic insular tumors: complication avoidance. J Neurosurg 95:638\u2013650. https:\/\/doi.org\/10.3171\/jns.2001.95.4.0638","journal-title":"J Neurosurg"},{"key":"3409_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.04.257","author":"F Lechanoine","year":"2019","unstructured":"Lechanoine F, Smirnov M, Armani GL, Carneiro P, Cottier P, Destrieux C, Maldonado IL (2019) Stereoscopic images from computed tomography angiograms. World Neurosurg. https:\/\/doi.org\/10.1016\/j.wneu.2019.04.257","journal-title":"World Neurosurg"},{"key":"3409_CR20","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s11060-020-03390-2","volume":"147","author":"Z Li","year":"2020","unstructured":"Li Z, Li G, Liu Z, Pan Y, Hou Z, Wu L, Huang Z, Zhang Y, Xie J (2020) Transcortical approach for insular gliomas: a series of 253 patients. J Neurooncol 147:59\u201366. https:\/\/doi.org\/10.1007\/s11060-020-03390-2","journal-title":"J Neurooncol"},{"key":"3409_CR21","volume-title":"Atlas humani cerebri","author":"E Ludwig","year":"1956","unstructured":"Ludwig E, Klingler J (1956) Atlas humani cerebri. Springer, New York"},{"key":"3409_CR22","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/joa.12055","volume":"223","author":"IL Maldonado","year":"2013","unstructured":"Maldonado IL, de Champfleur NM, Velut S, Destrieux C, Zemmoura I, Duffau H (2013) Evidence of a middle longitudinal fasciculus in the human brain from fiber dissection. J Anat 223:38\u201345. https:\/\/doi.org\/10.1111\/joa.12055","journal-title":"J Anat"},{"key":"3409_CR23","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.3171\/2020.7.JNS192846","volume":"135","author":"IL Maldonado","year":"2021","unstructured":"Maldonado IL, Destrieux C, Ribas EC, De Abreu S, Brito Guimar\u00e3es B, Cruz PP, Duffau H (2021) Composition and organization of the sagittal stratum in the human brain: a fiber dissection study. J Neurosurg 135:1214\u20131222. https:\/\/doi.org\/10.3171\/2020.7.JNS192846","journal-title":"J Neurosurg"},{"key":"3409_CR24","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/ar.21533","volume":"295","author":"IL Maldonado","year":"2012","unstructured":"Maldonado IL, Mandonnet E, Duffau H (2012) Dorsal fronto-parietal connections of the human brain: a fiber dissection study of their composition and anatomical relationships. Anat Rec Adv Integr Anat Evol Biol 295:187\u2013195. https:\/\/doi.org\/10.1002\/ar.21533","journal-title":"Anat Rec Adv Integr Anat Evol Biol"},{"key":"3409_CR25","doi-asserted-by":"publisher","first-page":"770","DOI":"10.3171\/2011.5.JNS112","volume":"115","author":"IL Maldonado","year":"2011","unstructured":"Maldonado IL, Moritz-Gasser S, de Champfleur NM, Bertram L, Moulinie G, Duffau H (2011) Surgery for gliomas involving the left inferior parietal lobule: new insights into the functional anatomy provided by stimulation mapping in awake patients. J Neurosurg 115:770\u2013779. https:\/\/doi.org\/10.3171\/2011.5.JNS112","journal-title":"J Neurosurg"},{"key":"3409_CR26","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.3171\/2014.11.JNS141992","volume":"123","author":"J Martino","year":"2015","unstructured":"Martino J, Mato D, de Lucas EM, Garc\u00eda-Porrero JA, Gabarr\u00f3s A, Fern\u00e1ndez-Coello A, V\u00e1zquez-Barquero A (2015) Subcortical anatomy as an anatomical and functional landmark in insulo-opercular gliomas: implications for surgical approach to the insular region. J Neurosurg 123:1081\u20131092. https:\/\/doi.org\/10.3171\/2014.11.JNS141992","journal-title":"J Neurosurg"},{"key":"3409_CR27","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s11060-016-2120-2","volume":"130","author":"K Michaud","year":"2016","unstructured":"Michaud K, Duffau H (2016) Surgery of insular and paralimbic diffuse low-grade gliomas: technical considerations. J Neurooncol 130:289\u2013298. https:\/\/doi.org\/10.1007\/s11060-016-2120-2","journal-title":"J Neurooncol"},{"key":"3409_CR28","doi-asserted-by":"publisher","first-page":"825","DOI":"10.3171\/JNS\/2008\/109\/11\/0825","volume":"109","author":"YA Moshel","year":"2008","unstructured":"Moshel YA, Marcus JDS, Parker EC, Kelly PJ (2008) Resection of insular gliomas: the importance of lenticulostriate artery position: clinical article. J Neurosurg 109:825\u2013834. https:\/\/doi.org\/10.3171\/JNS\/2008\/109\/11\/0825","journal-title":"J Neurosurg"},{"key":"3409_CR29","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.wneu.2017.07.166","volume":"107","author":"S Ookawa","year":"2017","unstructured":"Ookawa S, Enatsu R, Kanno A, Ochi S, Akiyama Y, Kobayashi T, Yamao Y, Kikuchi T, Matsumoto R, Kunieda T, Mikuni N (2017) Frontal fibers connecting the superior frontal gyrus to broca area: a corticocortical evoked potential study. World Neurosurg 107:239\u2013248. https:\/\/doi.org\/10.1016\/j.wneu.2017.07.166","journal-title":"World Neurosurg"},{"key":"3409_CR30","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.3171\/2018.12.JNS183075","volume":"132","author":"CJ Przybylowski","year":"2019","unstructured":"Przybylowski CJ, Baranoski JF, So VM, Wilson J, Sanai N (2019) Surgical morbidity of transsylvian versus transcortical approaches to insular gliomas. J Neurosurg 132:1731\u20131738. https:\/\/doi.org\/10.3171\/2018.12.JNS183075","journal-title":"J Neurosurg"},{"key":"3409_CR31","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1093\/brain\/awz021","volume":"142","author":"F Rech","year":"2019","unstructured":"Rech F, Herbet G, Gaudeau Y, M\u00e9zi\u00e8res S, Moureau J-M, Moritz-Gasser S, Duffau H (2019) A probabilistic map of negative motor areas of the upper limb and face: a brain stimulation study. Brain 142:952\u2013965. https:\/\/doi.org\/10.1093\/brain\/awz021","journal-title":"Brain"},{"key":"3409_CR32","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1056\/NEJMoa067819","volume":"358","author":"N Sanai","year":"2008","unstructured":"Sanai N, Mirzadeh Z, Berger MS (2008) Functional outcome after language mapping for glioma resection. N Engl J Med 358:18\u201327. https:\/\/doi.org\/10.1056\/NEJMoa067819","journal-title":"N Engl J Med"},{"key":"3409_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/2009.6.JNS0952","volume":"112","author":"N Sanai","year":"2010","unstructured":"Sanai N, Polley M-Y, Berger MS (2010) Insular glioma resection: assessment of patient morbidity, survival, and tumor progression. J Neurosurg 112:1\u20139. https:\/\/doi.org\/10.3171\/2009.6.JNS0952","journal-title":"J Neurosurg"},{"key":"3409_CR34","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1038\/s41598-022-26227-6","volume":"13","author":"M Smirnov","year":"2023","unstructured":"Smirnov M, Maldonado IL, Destrieux C (2023) Using ex vivo arterial injection and dissection to assess white matter vascularization. Sci Rep 13:809. https:\/\/doi.org\/10.1038\/s41598-022-26227-6","journal-title":"Sci Rep"},{"key":"3409_CR35","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3171\/2022.8.JNS22923","volume":"139","author":"G-C Sun","year":"2023","unstructured":"Sun G-C, Shu X-J, Zheng X-Q, Ma X-D, Cheng G, Liu J-L, Chen L, Zhang J-N (2023) The transfrontal isthmus approach for insular glioma surgery. J Neurosurg 139:20\u201328. https:\/\/doi.org\/10.3171\/2022.8.JNS22923","journal-title":"J Neurosurg"},{"key":"3409_CR36","doi-asserted-by":"publisher","first-page":"466","DOI":"10.3174\/ajnr.A3704","volume":"35","author":"A Tamura","year":"2014","unstructured":"Tamura A, Kasai T, Akazawa K, Nagakane Y, Yoshida T, Fujiwara Y, Kuriyama N, Yamada K, Mizuno T, Nakagawa M (2014) Long insular artery infarction: characteristics of a previously unrecognized entity. Am J Neuroradiol 35:466\u2013471. https:\/\/doi.org\/10.3174\/ajnr.A3704","journal-title":"Am J Neuroradiol"},{"key":"3409_CR37","doi-asserted-by":"publisher","first-page":"685","DOI":"10.3109\/02688697.2014.889810","volume":"28","author":"F Vassal","year":"2014","unstructured":"Vassal F, Boutet C, Lemaire J-J, Nuti C (2014) New insights into the functional significance of the frontal aslant tract: an anatomo\u2013functional study using intraoperative electrical stimulations combined with diffusion tensor imaging-based fiber tracking. Br J Neurosurg 28:685\u2013687. https:\/\/doi.org\/10.3109\/02688697.2014.889810","journal-title":"Br J Neurosurg"},{"key":"3409_CR38","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/BF01400725","volume":"118","author":"MG Ya\u015fargil","year":"1992","unstructured":"Ya\u015fargil MG, Von Ammon K, Cavazos E, Doczi T, Reeves JD, Roth P (1992) Tumours of the limbic and paralimbic systems. Acta Neurochir (Wien) 118:40\u201352. https:\/\/doi.org\/10.1007\/BF01400725","journal-title":"Acta Neurochir (Wien)"},{"key":"3409_CR39","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.neurol.2019.12.005","volume":"176","author":"R Yokoyama","year":"2020","unstructured":"Yokoyama R, Enatsu R, Kanno A, Suzuki H, Suzuki Y, Sasagawa A, Hirano T, Arihara M, Kuribara T, Ochi S, Mikuni N (2020) Negative motor networks: Electric cortical stimulation and diffusion tensor imaging. Rev Neurol (Paris) 176:592\u2013600. https:\/\/doi.org\/10.1016\/j.neurol.2019.12.005","journal-title":"Rev Neurol (Paris)"}],"container-title":["Surgical and Radiologic Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00276-024-03409-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00276-024-03409-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00276-024-03409-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T19:01:43Z","timestamp":1720897303000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00276-024-03409-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":39,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["3409"],"URL":"https:\/\/doi.org\/10.1007\/s00276-024-03409-7","relation":{},"ISSN":["1279-8517"],"issn-type":[{"value":"1279-8517","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,13]]},"assertion":[{"value":"9 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}]}}