{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T19:59:56Z","timestamp":1700164796594},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2003,6,26]],"date-time":"2003-06-26T00:00:00Z","timestamp":1056585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2003,8]]},"DOI":"10.1007\/s00277-003-0693-2","type":"journal-article","created":{"date-parts":[[2003,10,27]],"date-time":"2003-10-27T19:08:56Z","timestamp":1067281736000},"page":"476-480","source":"Crossref","is-referenced-by-count":10,"title":["High-dose hydroxyurea in the treatment of poor-risk myeloid leukemias"],"prefix":"10.1007","volume":"82","author":[{"given":"M. C.","family":"Petti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Tafuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Latagliata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Aloe Spiriti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Montefusco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mancini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Meloni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. T.","family":"Petrucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Spadea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Redi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Alimena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Mandelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2003,6,26]]},"reference":[{"key":"693_CR1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/1040-8428(95)00187-5","volume":"22","author":"Nocentini","year":"1996","unstructured":"Nocentini G (1996) Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy. Crit Rev Hematol 22:89\u2013126","journal-title":"Crit Rev Hematol"},{"key":"693_CR2","unstructured":"Chabner BA, Allegra CJ, Curt GA, et al. (1996) Antineoplastic agents. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman Gilman A (eds) Goodman & Gilman's the pharmacological basis of therapeutics, 9th edn. Mc Graw-Hill, New York, pp 1233\u20131287"},{"key":"693_CR3","first-page":"110","volume":"19","author":"Vaughan","year":"1992","unstructured":"Vaughan WP, Bierman PJ, Reed EC, Glenn LD, Kessinger A, Armitage JO (1992) High-dose hydroxyurea in autologous bone marrow transplantation: a promising \"new\" agent. Semin Oncol 19:110\u2013115","journal-title":"Semin Oncol"},{"key":"693_CR4","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1182\/blood.V91.5.1533","volume":"91","author":"Rodriguez","year":"1998","unstructured":"Rodriguez GI, Kuhn JG, Weiss GR, Hilsenbeck SG, Eckardt JR, Thurman A, Rinaldi DA, Hodges S, Von Hoff DD, Rowinsky EK (1998) A bioavailability and pharmacokinetic study of oral and intravenous hydroxyurea. Blood 91:1533\u20131541","journal-title":"Blood"},{"key":"693_CR5","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/S0165-4608(84)80022-9","volume":"11","author":"Bloomfield","year":"1984","unstructured":"Bloomfield CD, Goldman A, Hossfeld D, de la Chapelle A (1984) Fourth International Workshop on Chromosomes in Leukemia 1982: clinical significance of chromosomal abnormalities in acute non lymphoblastic leukemia. Cancer Genet Cytogenet 11:332\u2013350","journal-title":"Cancer Genet Cytogenet"},{"key":"693_CR6","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1182\/blood.V89.9.3323","volume":"89","author":"Leith","year":"1997","unstructured":"Leith CP, Copecky KJ, Godwin J, McConnell T, Slovak ML, Chen IM, Head DR, Appelbaum FR, Willman CL (1997) Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biological subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group Study. Blood 89:3323\u20133329","journal-title":"Blood"},{"key":"693_CR7","first-page":"378","volume":"31","author":"Von","year":"1990","unstructured":"Von Hoff D, Van Devantes D, Forseth B, et al. (1990) Hydroxyurea can decrease gene copy numbers in tumor cell lines (abstract). Proc Am Assoc Cancer Res 31:378","journal-title":"Proc Am Assoc Cancer Res"},{"key":"693_CR8","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/BF00685331","volume":"33","author":"Smith","year":"1993","unstructured":"Smith DC, Vaughan WP, Gwilt PR, Trump DL (1993) A phase I trial of high-dose continuous infusion of hydroxyurea. Cancer Chemother Pharmacol 33:139\u2013143","journal-title":"Cancer Chemother Pharmacol"},{"key":"693_CR9","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/1097-0142(19800801)46:3<455::AID-CNCR2820460306>3.0.CO;2-N","volume":"46","author":"Belt","year":"1980","unstructured":"Belt RJ, Haas CD, Kennedy J, Taylor S (1980) Studies of hydroxyurea administered by continuous infusion: toxicity, pharmacokinetics, and cell synchronization. Cancer 46:455\u2013462","journal-title":"Cancer"},{"key":"693_CR10","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1182\/blood.V32.4.507.507","volume":"32","author":"Ellison","year":"1968","unstructured":"Ellison RR, Holland JF, Weil M, Jacquillat C, Boiron M, Bernard J, Sawitsky A, Rosner F, Gussoff B, Silver RT, Karanas A, Cuttner J, Spurr CL, Hayes DM, Blom J, Leone LA, Haurani F, Kyle R, Hutchinson JL, Forcier RJ, Moon JH (1968) Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults. Blood 32:507\u2013510","journal-title":"Blood"},{"key":"693_CR11","unstructured":"World Health Organization (1979) Handbook for reporting results of cancer treatment. WHO offset publication 48. WHO, Geneva"},{"key":"693_CR12","unstructured":"Cuneo A, Bigoni R, Roberti MG, Bardi A, Rigolin GM, Piva N, Mancini M, Nanni M, Alimena G, Mecucci C, Matteucci C, La Starza R, Bernasconi P, Cavigliano P, Genini E, Zaccaria A, Testoni N, Carboni C, Castoldi G (1998) Detection and monitoring of trisomy 8 by fluorescence in situ hybridization in acute myeloid leukemia: a multicentric study Haematologica 83:21\u201326"},{"key":"693_CR13","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1182\/blood.V86.6.2329.bloodjournal8662329","volume":"86","author":"Leith","year":"1995","unstructured":"Leith CP, Chen IM, Kopecky KY, Appelbaum FR, Head DR, Godwin JE, Weick JK, Willman CL (1995) Correlation of multidrug resistance (MDR1) protein expression with functional dye\/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-\/efflux+ and MDR+\/efflux- cases. Blood 86:2329\u20132342","journal-title":"Blood"},{"key":"693_CR14","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1038\/sj.leu.2400656","volume":"11","author":"Marie","year":"1997","unstructured":"Marie JP, Huet S, Faussat AM, Perrot JY, Chevillard S, Barbu V, Bayle C, Boutonnat J, Calvo F, Campos-Guyotat L, Colosetti P, Cazin JL, de Cremoux P, Delvincourt C, Demour C, Drenou B, Fenneteau O, Feuillard J, Garnier-Suillerot A, Genne P, Gorisse MC, Gosselin P, Jouault H, Lacave R, Robert J (1997) Multicenter evaluation of the MDR phenotype in leukemia. Leukemia 11:1086\u20131094","journal-title":"Leukemia"},{"key":"693_CR15","first-page":"1086","volume":"94","author":"Leith","year":"1999","unstructured":"Leith CP, Kopecky KY, Chen IM, Eijdems L, Slovak ML, McConnell TS, Head DR, Weick J, Grever MR, Appelbaum FR Willman CL (1999) Frequency and clinical significance of the expression of the MDR protein MDR1\/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia. A Southwest Oncology Group Study. Blood 94:1086\u20131099","journal-title":"Blood"},{"key":"693_CR16","first-page":"5125","volume":"46","author":"Dalton","year":"1986","unstructured":"Dalton WS, Durie BGM, Alberts DS, Gerlach JH, Cress AE (1986) Characterization of a new drug resistance human myeloma cell line that expresses p-glycoprotein. Cancer Res 46:5125\u20135130","journal-title":"Cancer Res"},{"key":"693_CR17","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/0145-2126(95)00092-5","volume":"19","author":"Tafuri","year":"1995","unstructured":"Tafuri A, Sommaggio A, Burba L, Albergoni MP, Petrucci MT, Mascolo MG, Testi AM, Basso G (1995) Prognostic value of rhodamine-efflux and MDR1\/P-gp 170 expression in childhood acute leukemia. Leuk Res 19:927\u2013931","journal-title":"Leuk Res"},{"key":"693_CR18","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1056\/NEJM199410063311402","volume":"331","author":"Mayer","year":"1994","unstructured":"Mayer RJ, Davis RB, Schiffer CA, Berg DT, Powell BL, Schulman P, Omura GA, Moore JO, McIntyre OR, Frei E (1994) Intensive postremission chemotherapy in adults with acute myeloid leukemia. N Engl J Med 331:896\u2013903","journal-title":"N Engl J Med"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-003-0693-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00277-003-0693-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-003-0693-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-003-0693-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T10:39:31Z","timestamp":1623494371000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00277-003-0693-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,26]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["693"],"URL":"https:\/\/doi.org\/10.1007\/s00277-003-0693-2","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,26]]}}}