{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:00:26Z","timestamp":1785416426513,"version":"3.56.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T00:00:00Z","timestamp":1366329600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1007\/s00277-013-1737-x","type":"journal-article","created":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T11:44:28Z","timestamp":1366285468000},"page":"1121-1128","source":"Crossref","is-referenced-by-count":27,"title":["Ferritin concentrations correlate to outcome of hematopoietic stem cell transplantation but do not serve as biomarker of graft-versus-host disease"],"prefix":"10.1007","volume":"92","author":[{"given":"M.","family":"Gro\u00dfekatth\u00f6fer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. D.","family":"G\u00fccl\u00fc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lawitschka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Matthes-Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Minkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Seidel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,4,19]]},"reference":[{"issue":"2","key":"1737_CR1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.bbmt.2005.11.010","volume":"12","author":"KR Schultz","year":"2006","unstructured":"Schultz KR, Miklos DB, Fowler D, Cooke K, Shizuru J, Zorn E, Holler E, Ferrara J, Shulman H, Lee SJ, Martin P, Filipovich AH, Flowers ME, Weisdorf D, Couriel D, Lachenbruch PA, Mittleman B, Vogelsang GB, Pavletic SZ (2006) Toward biomarkers for chronic graft-versus-host disease: National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: III. Biomarker working group report. Biol Blood Marrow Transplant 12(2):126\u2013137. doi: 10.1016\/j.bbmt.2005.11.010","journal-title":"Biol Blood Marrow Transplant"},{"issue":"9674","key":"1737_CR2","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/S0140-6736(09)60237-3","volume":"373","author":"JL Ferrara","year":"2009","unstructured":"Ferrara JL, Levine JE, Reddy P, Holler E (2009) Graft-versus-host disease. Lancet 373(9674):1550\u20131561. doi: 10.1016\/S0140-6736(09)60237-3","journal-title":"Lancet"},{"issue":"5426","key":"1737_CR3","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1126\/science.285.5426.412","volume":"285","author":"WD Shlomchik","year":"1999","unstructured":"Shlomchik WD, Couzens MS, Tang CB, McNiff J, Robert ME, Liu J, Shlomchik MJ, Emerson SG (1999) Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285(5426):412\u2013415","journal-title":"Science"},{"issue":"6","key":"1737_CR4","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/nm0602-575","volume":"8","author":"T Teshima","year":"2002","unstructured":"Teshima T, Ordemann R, Reddy P, Gagin S, Liu C, Cooke KR, Ferrara JL (2002) Acute graft-versus-host disease does not require alloantigen expression on host epithelium. Nat Med 8(6):575\u2013581. doi: 10.1038\/nm0602-575","journal-title":"Nat Med"},{"issue":"9","key":"1737_CR5","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/nm1089","volume":"10","author":"CC Matte","year":"2004","unstructured":"Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD (2004) Donor APCs are required for maximal GVHD but not for GVL. Nat Med 10(9):987\u2013992. doi: 10.1038\/nm1089","journal-title":"Nat Med"},{"issue":"1","key":"1737_CR6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/nm.2597","volume":"18","author":"M Koyama","year":"2011","unstructured":"Koyama M, Kuns RD, Olver SD, Raffelt NC, Wilson YA, Don AL, Lineburg KE, Cheong M, Robb RJ, Markey KA, Varelias A, Malissen B, Hammerling GJ, Clouston AD, Engwerda CR, Bhat P, Macdonald KP, Hill GR (2011) Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nat Med 18(1):135\u2013142. doi: 10.1038\/nm.2597","journal-title":"Nat Med"},{"issue":"35","key":"1737_CR7","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.3748\/wjg.v13.i35.4707","volume":"13","author":"G Porto","year":"2007","unstructured":"Porto G, De Sousa M (2007) Iron overload and immunity. World J Gastroenterol 13(35):4707\u20134715","journal-title":"World J Gastroenterol"},{"issue":"3","key":"1737_CR8","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00702-010-0479-3","volume":"118","author":"RJ Ward","year":"2011","unstructured":"Ward RJ, Crichton RR, Taylor DL, Della Corte L, Srai SK, Dexter DT (2011) Iron and the immune system. J Neural Transm 118(3):315\u2013328. doi: 10.1007\/s00702-010-0479-3","journal-title":"J Neural Transm"},{"issue":"2","key":"1737_CR9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.4149\/neo_2012_024","volume":"59","author":"S Sivgin","year":"2012","unstructured":"Sivgin S, Baldane S, Kaynar L, Kurnaz F, Pala C, Ozturk A, Cetin M, Unal A, Eser B (2012) Pretransplant serum ferritin level may be a predictive marker for outcomes in patients having undergone allogeneic hematopoietic stem cell transplantation. Neoplasma 59(2):183\u2013190","journal-title":"Neoplasma"},{"issue":"12","key":"1737_CR10","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/bmt.2008.262","volume":"42","author":"V Pullarkat","year":"2008","unstructured":"Pullarkat V, Blanchard S, Tegtmeier B, Dagis A, Patane K, Ito J, Forman SJ (2008) Iron overload adversely affects outcome of allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 42(12):799\u2013805. doi: 10.1038\/bmt.2008.262","journal-title":"Bone Marrow Transplant"},{"issue":"2","key":"1737_CR11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.bbmt.2008.11.012","volume":"15","author":"K Kataoka","year":"2009","unstructured":"Kataoka K, Nannya Y, Hangaishi A, Imai Y, Chiba S, Takahashi T, Kurokawa M (2009) Influence of pretransplantation serum ferritin on nonrelapse mortality after myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 15(2):195\u2013204. doi: 10.1016\/j.bbmt.2008.11.012","journal-title":"Biol Blood Marrow Transplant"},{"issue":"10","key":"1737_CR12","doi-asserted-by":"crossref","first-page":"4586","DOI":"10.1182\/blood-2006-10-054924","volume":"109","author":"P Armand","year":"2007","unstructured":"Armand P, Kim HT, Cutler CS, Ho VT, Koreth J, Alyea EP, Soiffer RJ, Antin JH (2007) Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation. Blood 109(10):4586\u20134588. doi: 10.1182\/blood-2006-10-054924","journal-title":"Blood"},{"issue":"4","key":"1737_CR13","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/bmt.2011.122","volume":"47","author":"M Tanaka","year":"2012","unstructured":"Tanaka M, Tachibana T, Numata A, Takasaki H, Matsumoto K, Maruta A, Ishigatsubo Y, Kanamori H (2012) A prognostic score with pretransplant serum ferritin and disease status predicts outcome following reduced-intensity SCT. Bone Marrow Transplant 47(4):596\u2013597. doi: 10.1038\/bmt.2011.122 bmt2011122","journal-title":"Bone Marrow Transplant"},{"issue":"2","key":"1737_CR14","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s12032-010-9496-1","volume":"28","author":"A Wahlin","year":"2011","unstructured":"Wahlin A, Lorenz F, Fredriksson M, Remberger M, Wahlin BE, Hagglund H (2011) Hyperferritinemia is associated with low incidence of graft versus host disease, high relapse rate, and impaired survival in patients with blood disorders receiving allogeneic hematopoietic stem cell grafts. Med Oncol 28(2):552\u2013558. doi: 10.1007\/s12032-010-9496-1","journal-title":"Med Oncol"},{"issue":"2","key":"1737_CR15","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1182\/blood-2008-07-167098","volume":"113","author":"S Paczesny","year":"2009","unstructured":"Paczesny S, Krijanovski OI, Braun TM, Choi SW, Clouthier SG, Kuick R, Misek DE, Cooke KR, Kitko CL, Weyand A, Bickley D, Jones D, Whitfield J, Reddy P, Levine JE, Hanash SM, Ferrara JL (2009) A biomarker panel for acute graft-versus-host disease. Blood 113(2):273\u2013278. doi: 10.1182\/blood-2008-07-167098","journal-title":"Blood"},{"issue":"6","key":"1737_CR16","first-page":"825","volume":"15","author":"D Przepiorka","year":"1995","unstructured":"Przepiorka D, Weisdorf D, Martin P, Klingemann HG, Beatty P, Hows J, Thomas ED (1995) 1994 Consensus conference on acute GVHD grading. Bone Marrow Transplant 15(6):825\u2013828","journal-title":"Bone Marrow Transplant"},{"issue":"2","key":"1737_CR17","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1182\/blood-2006-01-0254","volume":"108","author":"WM Leisenring","year":"2006","unstructured":"Leisenring WM, Martin PJ, Petersdorf EW, Regan AE, Aboulhosn N, Stern JM, Aker SN, Salazar RC, McDonald GB (2006) An acute graft-versus-host disease activity index to predict survival after hematopoietic cell transplantation with myeloablative conditioning regimens. Blood 108(2):749\u2013755. doi: 10.1182\/blood-2006-01-0254","journal-title":"Blood"},{"issue":"2","key":"1737_CR18","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0002-9343(80)90380-0","volume":"69","author":"HM Shulman","year":"1980","unstructured":"Shulman HM, Sullivan KM, Weiden PL, McDonald GB, Striker GE, Sale GE, Hackman R, Tsoi MS, Storb R, Thomas ED (1980) Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients. Am J Med 69(2):204\u2013217","journal-title":"Am J Med"},{"issue":"12","key":"1737_CR19","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.bbmt.2005.09.004","volume":"11","author":"AH Filipovich","year":"2005","unstructured":"Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME (2005) National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I Diagnosis and staging working group report. Biol Blood Marrow Transplant 11(12):945\u2013956. doi: 10.1016\/j.bbmt.2005.09.004","journal-title":"Biol Blood Marrow Transplant"},{"issue":"2","key":"1737_CR20","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/pbc.21039","volume":"48","author":"JI Henter","year":"2007","unstructured":"Henter JI, Horne A, Arico M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G (2007) HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 48(2):124\u2013131. doi: 10.1002\/pbc.21039","journal-title":"Pediatr Blood Cancer"},{"issue":"6","key":"1737_CR21","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/pbc.21423","volume":"50","author":"CE Allen","year":"2008","unstructured":"Allen CE, Yu X, Kozinetz CA, McClain KL (2008) Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 50(6):1227\u20131235. doi: 10.1002\/pbc.21423","journal-title":"Pediatr Blood Cancer"},{"issue":"4","key":"1737_CR22","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/00043426-200205000-00013","volume":"24","author":"B Files","year":"2002","unstructured":"Files B, Brambilla D, Kutlar A, Miller S, Vichinsky E, Wang W, Granger S, Adams RJ (2002) Longitudinal changes in ferritin during chronic transfusion: a report from the Stroke Prevention Trial in Sickle Cell Anemia (STOP). J Pediatr Hematol Oncol 24(4):284\u2013290","journal-title":"J Pediatr Hematol Oncol"},{"issue":"8","key":"1737_CR23","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.bbagen.2010.03.011","volume":"1800","author":"W Wang","year":"2010","unstructured":"Wang W, Knovich MA, Coffman LG, Torti FM, Torti SV (2010) Serum ferritin: past, present and future. Biochim Biophys Acta 1800(8):760\u2013769. doi: 10.1016\/j.bbagen.2010.03.011S0304-4165(10)00085-1","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"1737_CR24","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1365-2141.1981.tb07238.x","volume":"49","author":"AM Konijn","year":"1981","unstructured":"Konijn AM, Carmel N, Levy R, Hershko C (1981) Ferritin synthesis in inflammation II. Mechanism of increased ferritin synthesis. Br J Haematol 49(3):361\u2013370","journal-title":"Br J Haematol"},{"issue":"2","key":"1737_CR25","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/bmt.2010.108","volume":"46","author":"J Kanda","year":"2011","unstructured":"Kanda J, Mizumoto C, Ichinohe T, Kawabata H, Saito T, Yamashita K, Kondo T, Takakura S, Ichiyama S, Uchiyama T, Ishikawa T (2011) Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 46(2):208\u2013216. doi: 10.1038\/bmt.2010.108","journal-title":"Bone Marrow Transplant"},{"issue":"5","key":"1737_CR26","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1111\/j.1478-3231.2011.02488.x","volume":"31","author":"P Manousou","year":"2011","unstructured":"Manousou P, Kalambokis G, Grillo F, Watkins J, Xirouchakis E, Pleguezuelo M, Leandro G, Arvaniti V, Germani G, Patch D, Calvaruso V, Mikhailidis DP, Dhillon AP, Burroughs AK (2011) Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients. Liver Int 31(5):730\u2013739. doi: 10.1111\/j.1478-3231.2011.02488.x","journal-title":"Liver Int"},{"issue":"6","key":"1737_CR27","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1080\/10245332.1999.11746478","volume":"4","author":"M Morado","year":"2000","unstructured":"Morado M, Ojeda E, Garcia-Bustos J, Aguado MJ, Arrieta R, Quevedo E, Navas A, Hernandez-Navarro F (2000) BMT: serum ferritin as risk factor for veno-occlusive disease of the liver. Prospective cohort study. Hematology 4(6):505\u2013512","journal-title":"Hematology"},{"issue":"12","key":"1737_CR28","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/bmt.2009.88","volume":"44","author":"JW Lee","year":"2009","unstructured":"Lee JW, Kang HJ, Kim EK, Kim H, Shin HY, Ahn HS (2009) Effect of iron overload and iron-chelating therapy on allogeneic hematopoietic SCT in children. Bone Marrow Transplant 44(12):793\u2013797. doi: 10.1038\/bmt.2009.88","journal-title":"Bone Marrow Transplant"},{"issue":"10","key":"1737_CR29","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/ajh.22104","volume":"86","author":"EP Alessandrino","year":"2011","unstructured":"Alessandrino EP, Angelucci E, Cazzola M, Porta MG, Di Bartolomeo P, Gozzini A, Malcovati L, Pioltelli P, Sica S, Bosi A (2011) Iron overload and iron chelation therapy in patients with myelodysplastic syndrome treated by allogeneic stem-cell transplantation: report from the working conference on iron chelation of the Gruppo Italiano Trapianto di Midollo Osseo. Am J Hematol 86(10):897\u2013902. doi: 10.1002\/ajh.22104","journal-title":"Am J Hematol"},{"issue":"4","key":"1737_CR30","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/bmt.2010.165","volume":"46","author":"KJ August","year":"2011","unstructured":"August KJ, Chiang KY, Bostick RM, Flanders WD, Waller EK, Langston A, Worthington-White D, Rowland P, Moore KF, Khoury HJ, Horan JT (2011) Biomarkers of immune activation to screen for severe, acute GVHD. Bone Marrow Transplant 46(4):601\u2013604. doi: 10.1038\/bmt.2010.165","journal-title":"Bone Marrow Transplant"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-013-1737-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00277-013-1737-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-013-1737-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T09:49:42Z","timestamp":1559036982000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00277-013-1737-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,19]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["1737"],"URL":"https:\/\/doi.org\/10.1007\/s00277-013-1737-x","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,19]]}}}