{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T07:40:35Z","timestamp":1715413235430},"reference-count":204,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T00:00:00Z","timestamp":1369785600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1007\/s00277-013-1783-4","type":"journal-article","created":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T08:33:37Z","timestamp":1369730017000},"page":"1151-1179","source":"Crossref","is-referenced-by-count":19,"title":["Clinical practice guidelines for diagnosis, treatment, and follow-up of patients with mantle cell lymphoma. Recommendations from the GEL\/TAMO Spanish Cooperative Group"],"prefix":"10.1007","volume":"92","author":[{"given":"Dolores","family":"Caballero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El\u00edas","family":"Campo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"L\u00f3pez-Guillermo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyes","family":"Arranz-S\u00e1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Gin\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Gonz\u00e1lez-Barca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel \u00c1ngel","family":"Canales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Gonz\u00e1lez-D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Orfao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,5,29]]},"reference":[{"issue":"7","key":"1783_CR1","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1002\/1097-0142(19820401)49:7<1429::AID-CNCR2820490720>3.0.CO;2-5","volume":"49","author":"DD Weisenburger","year":"1982","unstructured":"Weisenburger DD, Kim H, Rappaport H (1982) Mantle-zone lymphoma: a follicular variant of intermediate lymphocytic lymphoma. Cancer 49(7):1429\u20131438","journal-title":"Cancer"},{"issue":"4","key":"1783_CR2","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/cncr.23608","volume":"113","author":"Y Zhou","year":"2008","unstructured":"Zhou Y, Wang H, Fang W, Romaguer JE, Zhang Y, Delasalle KB, Kwak L, Yi Q et al (2008) Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004. Cancer 113(4):791\u2013798","journal-title":"Cancer"},{"issue":"4","key":"1783_CR3","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1200\/JCO.2008.16.8435","volume":"27","author":"A Herrmann","year":"2009","unstructured":"Herrmann A, Hoster E, Zwingers T, Brittinger G, Engelhard M, Meusers P, Reiser M, Forstpointner R et al (2009) Improvement of overall survival in advanced stage mantle cell lymphoma. J Clin Oncol 27(4):511\u2013518","journal-title":"J Clin Oncol"},{"key":"1783_CR4","unstructured":"U.S. Preventive Services Task Force. Definitions of levels of evidence and grades of recommendation. http:\/\/www.uspreventiveservicestaskforce.org\/uspstf08\/methods\/procmanual4.htm and http:\/\/www.uspreventiveservicestaskforce.org\/uspstf\/grades.htm#post . Accessed July 2011."},{"issue":"10","key":"1783_CR5","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nrc2230","volume":"7","author":"P Jares","year":"2007","unstructured":"Jares P, Colomer D, Campo E (2007) Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 7(10):750\u2013762","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"1783_CR6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S1535-6108(03)00028-X","volume":"3","author":"A Rosenwald","year":"2003","unstructured":"Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM et al (2003) The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell 3(2):185\u2013197","journal-title":"Cancer Cell"},{"issue":"8","key":"1783_CR7","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1182\/blood-2012-08-452284","volume":"121","author":"I Salaverria","year":"2012","unstructured":"Salaverria I, Royo C, Carvajal-Cuenca A, Clot G, Navarro A, Valera A, Song JY, Woroniecka R et al (2012) CCND2 rearrangements are the most frequent genetic events in cyclin D1-negative mantle cell lymphoma. Blood 121(8):1394\u20131402","journal-title":"Blood"},{"key":"1783_CR8","volume-title":"WHO classification of tumours of haemotopoietic and lymphoid tissues","author":"SH Swerdlow","year":"2008","unstructured":"Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (2008) WHO classification of tumours of haemotopoietic and lymphoid tissues, 4th edn. WHO Press, Geneva (Switzerland)","edition":"4"},{"issue":"Suppl 2","key":"1783_CR9","first-page":"S60","volume":"11","author":"P Meusers","year":"1997","unstructured":"Meusers P, Hense J, Brittinger G (1997) Mantle cell lymphoma: diagnostic criteria, clinical aspects and therapeutic problems. Leukemia 11(Suppl 2):S60\u2013S64","journal-title":"Leukemia"},{"issue":"11","key":"1783_CR10","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.3324\/haematol.2009.013359","volume":"94","author":"SA Pileri","year":"2009","unstructured":"Pileri SA, Falini B (2009) Mantle cell lymphoma. Haematologica 94(11):1488\u20131492","journal-title":"Haematologica"},{"issue":"12","key":"1783_CR11","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1002\/cncr.22715","volume":"109","author":"A Ferrer","year":"2007","unstructured":"Ferrer A, Salaverria I, Bosch F, Villamor N, Rozman M, Bea S, Gine E, Lopez-Guillermo A et al (2007) Leukemic involvement is a common feature in mantle cell lymphoma. Cancer 109(12):2473\u20132480","journal-title":"Cancer"},{"issue":"1","key":"1783_CR12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2141.2005.05716.x","volume":"131","author":"M Tiemann","year":"2005","unstructured":"Tiemann M, Schrader C, Klapper W, Dreyling MH, Campo E, Norton A, Berger F, Kluin P et al (2005) Histopathology, cell proliferation indices and clinical outcome in 304 patients with mantle cell lymphoma (MCL): a clinicopathological study from the European MCL Network. Br J Haematol 131(1):29\u201338","journal-title":"Br J Haematol"},{"issue":"4","key":"1783_CR13","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1200\/JCO.1997.15.4.1664","volume":"15","author":"A Majlis","year":"1997","unstructured":"Majlis A, Pugh WC, Rodriguez MA, Benedict WF, Cabanillas F (1997) Mantle cell lymphoma: correlation of clinical outcome and biologic features with three histologic variants. J Clin Oncol 15(4):1664\u20131671","journal-title":"J Clin Oncol"},{"issue":"12","key":"1783_CR14","doi-asserted-by":"crossref","first-page":"4975","DOI":"10.1182\/blood-2002-06-1864","volume":"101","author":"J Orchard","year":"2003","unstructured":"Orchard J, Garand R, Davis Z, Babbage G, Sahota S, Matutes E, Catovsky D, Thomas PW et al (2003) A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease. Blood 101(12):4975\u20134981","journal-title":"Blood"},{"issue":"1","key":"1783_CR15","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1034\/j.1600-0609.2002.00551.x","volume":"68","author":"MK Angelopoulou","year":"2002","unstructured":"Angelopoulou MK, Siakantariz MP, Vassilakopoulos TP, Kontopidou FN, Rassidakis GZ, Dimopoulou MN, Kittas C, Pangalis GA (2002) The splenic form of mantle cell lymphoma. Eur J Haematol 68(1):12\u201321","journal-title":"Eur J Haematol"},{"issue":"10","key":"1783_CR16","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1080\/10428190410001723331","volume":"45","author":"E Matutes","year":"2004","unstructured":"Matutes E, Parry-Jones N, Brito-Babapulle V, Wotherspoon A, Morilla R, Atkinson S, Elnenaei MO, Jain P et al (2004) The leukemic presentation of mantle-cell lymphoma: disease features and prognostic factors in 58 patients. Leuk Lymphoma 45(10):2007\u20132015","journal-title":"Leuk Lymphoma"},{"issue":"6","key":"1783_CR17","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/01.pas.0000126054.95798.94","volume":"28","author":"W Cheuk","year":"2004","unstructured":"Cheuk W, Wong KO, Wong CS, Chan JK (2004) Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody. Am J Surg Pathol 28(6):801\u2013807","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"1783_CR18","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1046\/j.1365-2141.2000.02303.x","volume":"110","author":"ED Remstein","year":"2000","unstructured":"Remstein ED, Kurtin PJ, Buno I, Bailey RJ, Proffitt J, Wyatt WA, Hanson CA, Dewald GW (2000) Diagnostic utility of fluorescence in situ hybridization in mantle-cell lymphoma. Br J Haematol 110(4):856\u2013862","journal-title":"Br J Haematol"},{"issue":"4","key":"1783_CR19","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/hon.2900020406","volume":"2","author":"J Gerdes","year":"1984","unstructured":"Gerdes J, Dallenbach F, Lennert K, Lemke H, Stein H (1984) Growth fractions in malignant non-Hodgkin\u2019s lymphomas (NHL) as determined in situ with the monoclonal antibody Ki-67. Hematol Oncol 2(4):365\u2013371","journal-title":"Hematol Oncol"},{"issue":"15","key":"1783_CR20","doi-asserted-by":"crossref","first-page":"e437","DOI":"10.1200\/JCO.2010.31.8006","volume":"29","author":"SA Rule","year":"2011","unstructured":"Rule SA, Poplar S, Evans PA, O\u2019Connor SJ, Owen RG (2011) Indolent mantle-cell lymphoma: immunoglobulin variable region heavy chain sequence analysis reveals evidence of disease 10\u00a0years prior to symptomatic clinical presentation. J Clin Oncol 29(15):e437\u2013e439","journal-title":"J Clin Oncol"},{"issue":"2","key":"1783_CR21","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1182\/blood-2007-06-095331","volume":"111","author":"E Hoster","year":"2008","unstructured":"Hoster E, Dreyling M, Klapper W, Gisselbrecht C, van Hoof A, Kluin-Nelemans HC, Pfreundschuh M, Reiser M et al (2008) A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma. Blood 111(2):558\u2013565","journal-title":"Blood"},{"issue":"7","key":"1783_CR22","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1200\/JCO.2006.09.4490","volume":"25","author":"D Jong de","year":"2007","unstructured":"de Jong D, Rosenwald A, Chhanabhai M, Gaulard P, Klapper W, Lee A, Sander B, Thorns C et al (2007) Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications\u2014a study from the Lunenburg Lymphoma Biomarker Consortium. J Clin Oncol 25(7):805\u2013812","journal-title":"J Clin Oncol"},{"issue":"2","key":"1783_CR23","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s12308-009-0036-x","volume":"2","author":"W Klapper","year":"2009","unstructured":"Klapper W, Hoster E, Determann O, Oschlies I, van der Laak J, Berger F, Bernd HW, Cabecadas J et al (2009) Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network. J Hematop 2(2):103\u2013111","journal-title":"J Hematop"},{"issue":"7","key":"1783_CR24","first-page":"2253","volume":"95","author":"Y Yatabe","year":"2000","unstructured":"Yatabe Y, Suzuki R, Tobinai K, Matsuno Y, Ichinohasama R, Okamoto M, Yamaguchi M, Tamaru J et al (2000) Significance of cyclin D1 overexpression for the diagnosis of mantle cell lymphoma: a clinicopathologic comparison of cyclin D1-positive MCL and cyclin D1-negative MCL-like B-cell lymphoma. Blood 95(7):2253\u20132261","journal-title":"Blood"},{"issue":"5","key":"1783_CR25","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3324\/haematol.13030","volume":"93","author":"S Bea","year":"2008","unstructured":"Bea S, Campo E (2008) Secondary genomic alterations in non-Hodgkin\u2019s lymphomas: tumor-specific profiles with impact on clinical behavior. Haematologica 93(5):641\u2013645","journal-title":"Haematologica"},{"issue":"11","key":"1783_CR26","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.3324\/haematol.2009.010264","volume":"94","author":"A Mozos","year":"2009","unstructured":"Mozos A, Royo C, Hartmann E, De Jong D, Baro C, Valera A, Fu K, Weisenburger DD et al (2009) SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica 94(11):1555\u20131562","journal-title":"Haematologica"},{"issue":"2","key":"1783_CR27","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1182\/blood-2007-06-093401","volume":"111","author":"S Ek","year":"2008","unstructured":"Ek S, Dictor M, Jerkeman M, Jirstrom K, Borrebaeck CA (2008) Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma. Blood 111(2):800\u2013805","journal-title":"Blood"},{"issue":"8","key":"1783_CR28","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1200\/JCO.2008.19.6121","volume":"27","author":"P Martin","year":"2009","unstructured":"Martin P, Chadburn A, Christos P, Weil K, Furman RR, Ruan J, Elstrom R, Niesvizky R et al (2009) Outcome of deferred initial therapy in mantle-cell lymphoma. J Clin Oncol 27(8):1209\u20131213","journal-title":"J Clin Oncol"},{"issue":"4","key":"1783_CR29","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1158\/0008-5472.CAN-09-3419","volume":"70","author":"V Fern\u00e0ndez","year":"2010","unstructured":"Fern\u00e0ndez V, Salamero O, Espinet B, Sol\u00e9 F, Royo C, Navarro A, Camacho F, Bea S et al (2010) Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma. Cancer Res 70(4):1408\u20131418","journal-title":"Cancer Res"},{"issue":"20","key":"1783_CR30","doi-asserted-by":"crossref","first-page":"5307","DOI":"10.1158\/0008-5472.CAN-12-1615","volume":"72","author":"A Navarro","year":"2012","unstructured":"Navarro A, Clot G, Royo C, Jares P, Hadzidimitriou A, Agathangelidis A, Bikos V, Darzentas N et al (2012) Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features. Cancer Res 72(20):5307\u20135316","journal-title":"Cancer Res"},{"issue":"8","key":"1783_CR31","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.3324\/haematol.2010.036277","volume":"96","author":"SL Ondrejka","year":"2011","unstructured":"Ondrejka SL, Lai R, Kumar N, Smith SD, Hsi ED (2011) Indolent mantle cell leukemia: clinicopathologic variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis. Haematologica 96(8):1121\u20131127","journal-title":"Haematologica"},{"issue":"8","key":"1783_CR32","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1038\/leu.2012.72","volume":"26","author":"C Royo","year":"2012","unstructured":"Royo C, Navarro A, Clot G, Salaverria I, Gine E, Jares P, Colomer D, Wiestner A et al (2012) Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease. Leuk Off Journal Leuk Soc Am Leuk Res Fund UK 26(8):1895\u20131898","journal-title":"Leuk Off Journal Leuk Soc Am Leuk Res Fund UK"},{"issue":"18","key":"1783_CR33","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1182\/blood-2011-12-400580","volume":"119","author":"L Nygren","year":"2012","unstructured":"Nygren L, Baumgartner Wennerholm S, Klimkowska M, Christensson B, Kimby E, Sander B (2012) Prognostic role of SOX11 in a population-based cohort of mantle cell lymphoma. Blood 119(18):4215\u20134223","journal-title":"Blood"},{"issue":"2","key":"1783_CR34","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1365-2141.2008.07329.x","volume":"143","author":"X Wang","year":"2008","unstructured":"Wang X, Asplund AC, Porwit A, Flygare J, Smith CI, Christensson B, Sander B (2008) The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival. Br J Haematol 143(2):248\u2013252","journal-title":"Br J Haematol"},{"issue":"2","key":"1783_CR35","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3324\/haematol.2011.052621","volume":"97","author":"A Carvajal-Cuenca","year":"2012","unstructured":"Carvajal-Cuenca A, Sua LF, Silva NM, Pittaluga S, Royo C, Song JY, Sargent RL, Espinet B et al (2012) In situ mantle cell lymphoma: clinical implications of an incidental finding with indolent clinical behavior. Haematologica 97(2):270\u2013278","journal-title":"Haematologica"},{"issue":"19","key":"1783_CR36","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.1182\/blood-2011-01-293050","volume":"117","author":"E Campo","year":"2011","unstructured":"Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES (2011) The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood 117(19):5019\u20135032","journal-title":"Blood"},{"issue":"3","key":"1783_CR37","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/oxfordjournals.annonc.a059155","volume":"6","author":"E Zucca","year":"1995","unstructured":"Zucca E, Roggero E, Pinotti G, Pedrinis E, Cappella C, Venco A, Cavalli F (1995) Patterns of survival in mantle cell lymphoma. Ann Oncol 6(3):257\u2013262","journal-title":"Ann Oncol"},{"issue":"3","key":"1783_CR38","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/(SICI)1097-0142(19980201)82:3<567::AID-CNCR20>3.0.CO;2-Z","volume":"82","author":"F Bosch","year":"1998","unstructured":"Bosch F, Lopez-Guillermo A, Campo E, Ribera JM, Conde E, Piris MA, Vallespi T, Woessner S et al (1998) Mantle cell lymphoma: presenting features, response to therapy, and prognostic factors. Cancer 82(3):567\u2013575","journal-title":"Cancer"},{"issue":"3","key":"1783_CR39","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/1096-8652(200007)64:3<190::AID-AJH9>3.0.CO;2-B","volume":"64","author":"DD Weisenburger","year":"2000","unstructured":"Weisenburger DD, Vose JM, Greiner TC, Lynch JC, Chan WC, Bierman PJ, Dave BJ, Sanger WG et al (2000) Mantle cell lymphoma. A clinicopathologic study of 68 cases from the Nebraska Lymphoma Study Group. Am J Hematol 64(3):190\u2013196","journal-title":"Am J Hematol"},{"issue":"4","key":"1783_CR40","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1365-2559.2005.02323.x","volume":"48","author":"M Parrens","year":"2006","unstructured":"Parrens M, Belaud-Rotureau MA, Fitoussi O, Carerre N, Bouabdallah K, Marit G, Dubus P, de Mascarel A et al (2006) Blastoid and common variants of mantle cell lymphoma exhibit distinct immunophenotypic and interphase FISH features. Histopathology 48(4):353\u2013362","journal-title":"Histopathology"},{"issue":"11","key":"1783_CR41","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1038\/sj.leu.2402272","volume":"15","author":"M Bernard","year":"2001","unstructured":"Bernard M, Gressin R, Lefrere F, Drenou B, Branger B, Caulet-Maugendre S, Tass P, Brousse N et al (2001) Blastic variant of mantle cell lymphoma: a rare but highly aggressive subtype. Leukemia 15(11):1785\u20131791","journal-title":"Leukemia"},{"issue":"1","key":"1783_CR42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1034\/j.1600-0609.2002.01677.x","volume":"69","author":"R R\u00e4ty","year":"2002","unstructured":"R\u00e4ty R, Franssila K, Joensuu H, Teerenhovi L, Elonen E (2002) Ki-67 expression level, histological subtype, and the International Prognostic Index as outcome predictors in mantle cell lymphoma. Eur J Haematol 69(1):11\u201320","journal-title":"Eur J Haematol"},{"issue":"8","key":"1783_CR43","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1182\/blood.V87.8.3351.bloodjournal8783351","volume":"87","author":"L Hernandez","year":"1996","unstructured":"Hernandez L, Fest T, Cazorla M, Teruya-Feldstein J, Bosch F, Peinado MA, Piris MA, Montserrat E et al (1996) p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas. Blood 87(8):3351\u20133359","journal-title":"Blood"},{"issue":"8","key":"1783_CR44","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1182\/blood.V86.8.2892.2892","volume":"86","author":"DC Louie","year":"1995","unstructured":"Louie DC, Offit K, Jaslow R, Parsa NZ, Murty VV, Schluger A, Chaganti RS (1995) p53 overexpression as a marker of poor prognosis in mantle cell lymphomas with t(11;14)(q13;q32). Blood 86(8):2892\u20132899","journal-title":"Blood"},{"issue":"3","key":"1783_CR45","first-page":"699","volume":"36","author":"L Stefancikova","year":"2010","unstructured":"Stefancikova L, Moulis M, Fabian P, Ravcukova B, Vasova I, Muzik J, Malcikova J, Falkova I et al (2010) Loss of the p53 tumor suppressor activity is associated with negative prognosis of mantle cell lymphoma. Int J Oncol 36(3):699\u2013706","journal-title":"Int J Oncol"},{"issue":"2","key":"1783_CR46","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1365-2141.2007.06526.x","volume":"137","author":"N Parry-Jones","year":"2007","unstructured":"Parry-Jones N, Matutes E, Morilla R, Brito-Babapulle V, Wotherspoon A, Swansbury GJ, Catovsky D (2007) Cytogenetic abnormalities additional to t(11;14) correlate with clinical features in leukaemic presentation of mantle cell lymphoma, and may influence prognosis: a study of 60 cases by FISH. Br J Haematol 137(2):117\u2013124","journal-title":"Br J Haematol"},{"issue":"12","key":"1783_CR47","first-page":"4365","volume":"93","author":"S Be\u00e0","year":"1999","unstructured":"Be\u00e0 S, Ribas M, Hernandez JM, Bosch F, Pinyol M, Hernandez L, Garcia JL, Flores T et al (1999) Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants. Blood 93(12):4365\u20134374","journal-title":"Blood"},{"issue":"5","key":"1783_CR48","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/gcc.20754","volume":"49","author":"B Espinet","year":"2010","unstructured":"Espinet B, Salaverria I, Bea S, Ruiz-Xiville N, Balague O, Salido M, Costa D, Carreras J et al (2010) Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma. Genes Chromosomes Cancer 49(5):439\u2013451","journal-title":"Genes Chromosomes Cancer"},{"issue":"10","key":"1783_CR49","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1200\/JCO.2006.08.4251","volume":"25","author":"I Salaverria","year":"2007","unstructured":"Salaverria I, Zettl A, Bea S, Moreno V, Valls J, Hartmann E, Ott G, Wright G et al (2007) Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature. J Clin Oncol 25(10):1216\u20131222","journal-title":"J Clin Oncol"},{"issue":"3","key":"1783_CR50","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0959-8049(01)00366-5","volume":"38","author":"NS Andersen","year":"2002","unstructured":"Andersen NS, Jensen MK, de Nully BP, Geisler CH (2002) A Danish population-based analysis of 105 mantle cell lymphoma patients: incidences, clinical features, response, survival and prognostic factors. Eur J Cancer 38(3):401\u2013408","journal-title":"Eur J Cancer"},{"issue":"6","key":"1783_CR51","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1182\/blood.V89.6.2067","volume":"89","author":"LH Argatoff","year":"1997","unstructured":"Argatoff LH, Connors JM, Klasa RJ, Horsman DE, Gascoyne RD (1997) Mantle cell lymphoma: a clinicopathologic study of 80 cases. Blood 89(6):2067\u20132078","journal-title":"Blood"},{"issue":"3","key":"1783_CR52","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0959-8049(97)10056-9","volume":"34","author":"R Oinonen","year":"1998","unstructured":"Oinonen R, Franssila K, Teerenhovi L, Lappalainen K, Elonen E (1998) Mantle cell lymphoma: clinical features, treatment and prognosis of 94 patients. Eur J Cancer 34(3):329\u2013336","journal-title":"Eur J Cancer"},{"issue":"8","key":"1783_CR53","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/sj.leu.2401121","volume":"12","author":"H Samaha","year":"1998","unstructured":"Samaha H, Dumontet C, Ketterer N, Moullet I, Thieblemont C, Bouafia F, Callet-Bauchu E, Felman P et al (1998) Mantle cell lymphoma: a retrospective study of 121 cases. Leukemia 12(8):1281\u20131287","journal-title":"Leukemia"},{"issue":"8","key":"1783_CR54","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1182\/blood-2009-08-236570","volume":"115","author":"CH Geisler","year":"2010","unstructured":"Geisler CH, Kolstad A, Laurell A, Raty R, Jerkeman M, Eriksson M, Nordstrom M, Kimby E et al (2010) The Mantle Cell Lymphoma International Prognostic Index (MIPI) is superior to the International Prognostic Index (IPI) in predicting survival following intensive first-line immunochemotherapy and autologous stem cell transplantation (ASCT). Blood 115(8):1530\u20131533","journal-title":"Blood"},{"issue":"9","key":"1783_CR55","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.3324\/haematol.2009.021113","volume":"95","author":"SA Schans van de","year":"2010","unstructured":"van de Schans SA, Janssen-Heijnen ML, Nijziel MR, Steyerberg EW, van Spronsen DJ (2010) Validation, revision and extension of the Mantle Cell Lymphoma International Prognostic Index in a population-based setting. Haematologica 95(9):1503\u20131509","journal-title":"Haematologica"},{"issue":"8","key":"1783_CR56","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1182\/blood-2009-02-179739","volume":"114","author":"M Ghielmini","year":"2009","unstructured":"Ghielmini M, Zucca E (2009) How I treat mantle cell lymphoma. Blood 114(8):1469\u20131476","journal-title":"Blood"},{"issue":"1","key":"1783_CR57","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1182\/asheducation-2009.1.542","volume":"2009","author":"M Dreyling","year":"2009","unstructured":"Dreyling M, Hiddemann W, for The European MCLN (2009) Current treatment standards and emerging strategies in mantle cell lymphoma. Hematology 2009(1):542\u2013551","journal-title":"Hematology"},{"issue":"10","key":"1783_CR58","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1093\/annonc\/mdg414","volume":"14","author":"HA Leitch","year":"2003","unstructured":"Leitch HA, Gascoyne RD, Chhanabhai M, Voss NJ, Klasa R, Connors JM (2003) Limited-stage mantle-cell lymphoma. Ann Oncol 14(10):1555\u20131561","journal-title":"Ann Oncol"},{"issue":"7","key":"1783_CR59","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1093\/annonc\/mdn045","volume":"19","author":"P Martin","year":"2008","unstructured":"Martin P, Chadburn A, Christos P, Furman R, Ruan J, Joyce MA, Fusco E, Glynn P et al (2008) Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma: overall survival exceeding 7\u00a0years with standard therapies. Ann Oncol 19(7):1327\u20131330","journal-title":"Ann Oncol"},{"issue":"9873","key":"1783_CR60","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/S0140-6736(12)61763-2","volume":"381","author":"MJ Rummel","year":"2013","unstructured":"Rummel MJ, Niederle N, Maschmeyer G, Banat GA, von Gr\u00fcnhagen U, Losem C, Kofahl-Krause D, Heil G et al (2013) Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial. Lancet 381(9873):1203\u20131210","journal-title":"Lancet"},{"issue":"4","key":"1783_CR61","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1200\/JCO.2005.04.164","volume":"23","author":"M Ghielmini","year":"2005","unstructured":"Ghielmini M, Schmitz SF, Cogliatti S, Bertoni F, Waltzer U, Fey MF, Betticher DC, Schefer H et al (2005) Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol 23(4):705\u2013711","journal-title":"J Clin Oncol"},{"issue":"9","key":"1783_CR62","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1093\/jnci\/djk152","volume":"99","author":"H Schulz","year":"2007","unstructured":"Schulz H, Bohlius JF, Trelle S, Skoetz N, Reiser M, Kober T, Schwarzer G, Herold M et al (2007) Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis. J Natl Cancer Inst 99(9):706\u2013714","journal-title":"J Natl Cancer Inst"},{"issue":"10","key":"1783_CR63","doi-asserted-by":"crossref","first-page":"3064","DOI":"10.1182\/blood-2004-04-1323","volume":"104","author":"R Forstpointner","year":"2004","unstructured":"Forstpointner R, Dreyling M, Repp R, Hermann S, Hanel A, Metzner B, Pott C, Hartmann F et al (2004) The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood 104(10):3064\u20133071","journal-title":"Blood"},{"issue":"9","key":"1783_CR64","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1200\/JCO.2005.08.133","volume":"23","author":"G Lenz","year":"2005","unstructured":"Lenz G, Dreyling M, Hoster E, Wormann B, Duhrsen U, Metzner B, Eimermacher H, Neubauer A et al (2005) Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG). J Clin Oncol 23(9):1984\u20131992","journal-title":"J Clin Oncol"},{"key":"1783_CR65","doi-asserted-by":"crossref","unstructured":"Herold M, Pasold R, Srock S, Neser S, Niederwieser D, Neubauer A (2004) Results of a prospective randomised open label phase III study comparing rituximab plus mitoxantrone, chlorambucile, prednisolone chemotherapy (R-MCP) versus MCP alone in untreated advanced indolent non-Hodgkin\u2019s lymphoma (NHL) and mantle-cell-lymphoma (MCL). Blood 104 (11 ASH annual meeting abstracts):169","DOI":"10.1182\/blood.V104.11.584.584"},{"issue":"2","key":"1783_CR66","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1182\/blood-2002-08-2476","volume":"102","author":"AM Gianni","year":"2003","unstructured":"Gianni AM, Magni M, Martelli M, Di Nicola M, Carlo-Stella C, Pilotti S, Rambaldi A, Cortelazzo S et al (2003) Long-term remission in mantle cell lymphoma following high-dose sequential chemotherapy and in vivo rituximab-purged stem cell autografting (R-HDS regimen). Blood 102(2):749\u2013755","journal-title":"Blood"},{"issue":"4","key":"1783_CR67","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/sj.leu.2402406","volume":"16","author":"F Lefr\u00e8re","year":"2002","unstructured":"Lefr\u00e8re F, Delmer A, Suzan F, Levy V, Belanger C, Djabarri M, Arnulf B, Damaj G et al (2002) Sequential chemotherapy by CHOP and DHAP regimens followed by high-dose therapy with stem cell transplantation induces a high rate of complete response and improves event-free survival in mantle cell lymphoma: a prospective study. Leukemia 16(4):587\u2013593","journal-title":"Leukemia"},{"key":"1783_CR68","doi-asserted-by":"crossref","unstructured":"van 't Veer MB, de Jong D, MacKenzie M, Kluin-Nelemans HC, van Oers MH, Zijlstra J, Hagenbeek A, van Putten WL (2009) High-dose Ara-C and beam with autograft rescue in RCHOP responsive mantle cell lymphoma patients. Br J Haematol 144(4):524\u2013530","DOI":"10.1111\/j.1365-2141.2008.07498.x"},{"issue":"10","key":"1783_CR69","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1200\/JCO.2005.08.012","volume":"23","author":"IF Khouri","year":"2005","unstructured":"Khouri IF, Saliba RM, Hosing C, Okoroji GJ, Acholonu S, Anderlini P, Couriel D, De Lima M et al (2005) Concurrent administration of high-dose rituximab before and after autologous stem-cell transplantation for relapsed aggressive B-cell non-Hodgkin\u2019s lymphomas. J Clin Oncol 23(10):2240\u20132247","journal-title":"J Clin Oncol"},{"issue":"28","key":"1783_CR70","doi-asserted-by":"crossref","first-page":"7013","DOI":"10.1200\/JCO.2005.01.1825","volume":"23","author":"JE Romaguera","year":"2005","unstructured":"Romaguera JE, Fayad L, Rodriguez MA, Broglio KR, Hagemeister FB, Pro B, McLaughlin P, Younes A et al (2005) High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine. J Clin Oncol 23(28):7013\u20137023","journal-title":"J Clin Oncol"},{"issue":"2","key":"1783_CR71","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-2141.2010.08228.x","volume":"150","author":"JE Romaguera","year":"2010","unstructured":"Romaguera JE, Fayad LE, Feng L, Hartig K, Weaver P, Rodriguez MA, Hagemeister FB, Pro B et al (2010) Ten-year follow-up after intense chemoimmunotherapy with Rituximab-HyperCVAD alternating with Rituximab-high dose methotrexate\/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma. Br J Haematol 150(2):200\u2013208","journal-title":"Br J Haematol"},{"key":"1783_CR72","doi-asserted-by":"crossref","unstructured":"Epner EM, Unger J, Miller T, Rimzsa L, Spier C, Leblanc M, Fisher R (2007) A Multi center trial of hyperCVAD\u2009+\u2009Rituxan in patients with newly diagnosed mantle cell lymphoma. Blood 110 (11 ASH annual meeting abstracts):387","DOI":"10.1182\/blood.V110.11.387.387"},{"issue":"36","key":"1783_CR73","doi-asserted-by":"crossref","first-page":"6101","DOI":"10.1200\/JCO.2009.22.2554","volume":"27","author":"LE Damon","year":"2009","unstructured":"Damon LE, Johnson JL, Niedzwiecki D, Cheson BD, Hurd DD, Bartlett NL, Lacasce AS, Blum KA et al (2009) Immunochemotherapy and autologous stem-cell transplantation for untreated patients with mantle-cell lymphoma: CALGB 59909. J Clin Oncol 27(36):6101\u20136108","journal-title":"J Clin Oncol"},{"issue":"8","key":"1783_CR74","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.3324\/haematol.2010.025627","volume":"95","author":"CH Geisler","year":"2010","unstructured":"Geisler CH (2010) Front-line treatment of mantle cell lymphoma. Haematologica 95(8):1241\u20131243","journal-title":"Haematologica"},{"key":"1783_CR75","unstructured":"Pott C, Hoster E, Beldjord K, Macintyre EA, Bottcher S, Asnafi V, Siebert R, Plonquet A et al. (2010) R-CHOP\/R-DHAP compared to R-CHOP induction followed by high dose therapy with autologous stem cell transplantation induces higher rates of molecular remission. In: MCL: results of the MCL Younger Intergroup Trial of the European MCL Network. Blood 116 (21 ASH Annual Meeting Abstracts):965"},{"key":"1783_CR76","doi-asserted-by":"crossref","unstructured":"Hermine O, Hoster E, Walewski J, Ribrag V, Brousse N, Thieblemont C, Bouabdallah R, Dohner H et al. (2012) Alternating courses of 3\u00d7 CHOP and 3\u00d7 DHAP Plus rituximab followed by a high dose ARA-C containing myeloablative regimen and autologous stem cell transplantation (ASCT) increases overall survival when compared to 6 courses of CHOP plus rituximab followed by myeloablative radiochemotherapy and ASCT in mantle cell lymphoma: final analysis of the MCL Younger Trial of the European Mantle Cell Lymphoma Network (MCL net). Blood 120 (21 ASH Annual Meeting Abstracts):151","DOI":"10.1182\/blood.V120.21.151.151"},{"issue":"7","key":"1783_CR77","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1182\/blood-2004-10-3883","volume":"105","author":"M Dreyling","year":"2005","unstructured":"Dreyling M, Lenz G, Hoster E, Van Hoof A, Gisselbrecht C, Schmits R, Metzner B, Truemper L et al (2005) Early consolidation by myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission significantly prolongs progression-free survival in mantle-cell lymphoma: results of a prospective randomized trial of the European MCL Network. Blood 105(7):2677\u20132684","journal-title":"Blood"},{"issue":"2","key":"1783_CR78","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1034\/j.1600-0609.2003.00093.x","volume":"71","author":"NS Andersen","year":"2003","unstructured":"Andersen NS, Pedersen L, Elonen E, Johnson A, Kolstad A, Franssila K, Langholm R, Ralfkiaer E et al (2003) Primary treatment with autologous stem cell transplantation in mantle cell lymphoma: outcome related to remission pretransplant. Eur J Haematol 71(2):73\u201380","journal-title":"Eur J Haematol"},{"issue":"7","key":"1783_CR79","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1182\/blood-2008-03-147025","volume":"112","author":"CH Geisler","year":"2008","unstructured":"Geisler CH, Kolstad A, Laurell A, Andersen NS, Pedersen LB, Jerkeman M, Eriksson M, Nordstrom M et al (2008) Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group. Blood 112(7):2687\u20132693","journal-title":"Blood"},{"key":"1783_CR80","unstructured":"Geisler CH. Update of the Nordic MCL2 trial update: 10-year survival 57% following intensive immunotherapy and ASCT, but late relapses do occur. In: 11th International Conference on Malignant Lymphoma, Lugano, Switzerland. June 15\u201318, 2011"},{"issue":"18","key":"1783_CR81","doi-asserted-by":"crossref","first-page":"4144","DOI":"10.1182\/blood-2008-10-184200","volume":"113","author":"CS Tam","year":"2009","unstructured":"Tam CS, Bassett R, Ledesma C, Korbling M, Alousi A, Hosing C, Kebraei P, Harrell R et al (2009) Mature results of the M.D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma. Blood 113(18):4144\u20134152","journal-title":"Blood"},{"issue":"16","key":"1783_CR82","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1182\/blood-2009-06-230250","volume":"115","author":"C Pott","year":"2010","unstructured":"Pott C, Hoster E, Delfau-Larue MH, Beldjord K, Bottcher S, Asnafi V, Plonquet A, Siebert R et al (2010) Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study. Blood 115(16):3215\u20133223","journal-title":"Blood"},{"issue":"5","key":"1783_CR83","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1200\/JCO.20.5.1288","volume":"20","author":"OM Howard","year":"2002","unstructured":"Howard OM, Gribben JG, Neuberg DS, Grossbard M, Poor C, Janicek MJ, Shipp MA (2002) Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival. J Clin Oncol 20(5):1288\u20131294","journal-title":"J Clin Oncol"},{"issue":"22","key":"1783_CR84","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1200\/JCO.2010.33.7055","volume":"29","author":"LE Budde","year":"2011","unstructured":"Budde LE, Guthrie KA, Till BG, Press OW, Chauncey TR, Pagel JM, Petersdorf SH, Bensinger WI et al (2011) Mantle cell lymphoma international prognostic index but not pretransplantation induction regimen predicts survival for patients with mantle-cell lymphoma receiving high-dose therapy and autologous stem-cell transplantation. J Clin Oncol 29(22):3023\u20133029","journal-title":"J Clin Oncol"},{"issue":"22","key":"1783_CR85","doi-asserted-by":"crossref","first-page":"4626","DOI":"10.1200\/JCO.2004.02.175","volume":"22","author":"L Talarico","year":"2004","unstructured":"Talarico L, Chen G, Pazdur R (2004) Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol 22(22):4626\u20134631","journal-title":"J Clin Oncol"},{"issue":"2","key":"1783_CR86","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/annonc\/mdq609","volume":"22","author":"M Aapro","year":"2011","unstructured":"Aapro M, Bernard-Marty C, Brain EG, Batist G, Erdkamp F, Krzemieniecki K, Leonard R, Lluch A et al (2011) Anthracycline cardiotoxicity in the elderly cancer patient: a SIOG expert position paper. Ann Oncol 22(2):257\u2013267","journal-title":"Ann Oncol"},{"issue":"5","key":"1783_CR87","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/hon.2900070505","volume":"7","author":"P Meusers","year":"1989","unstructured":"Meusers P, Engelhard M, Bartels H, Binder T, Fulle HH, Gorg K, Gunzer U, Havemann K et al (1989) Multicentre randomized therapeutic trial for advanced centrocytic lymphoma: anthracycline does not improve the prognosis. Hematol Oncol 7(5):365\u2013380","journal-title":"Hematol Oncol"},{"issue":"47","key":"1783_CR88","doi-asserted-by":"crossref","first-page":"7359","DOI":"10.1038\/sj.onc.1206939","volume":"22","author":"MR Smith","year":"2003","unstructured":"Smith MR (2003) Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance. Oncogene 22(47):7359\u20137368","journal-title":"Oncogene"},{"issue":"6","key":"1783_CR89","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1056\/NEJMoa1200920","volume":"367","author":"HC Kluin-Nelemans","year":"2012","unstructured":"Kluin-Nelemans HC, Hoster E, Hermine O, Walewski J, Trneny M, Geisler CH, Stilgenbauer S, Thieblemont C et al (2012) Treatment of older patients with mantle-cell lymphoma. N Engl J Med 367(6):520\u2013531","journal-title":"N Engl J Med"},{"issue":"1","key":"1783_CR90","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/annonc\/mdr035","volume":"23","author":"E Jantunen","year":"2012","unstructured":"Jantunen E, Canals C, Attal M, Thomson K, Milpied N, Buzyn A, Ferrant A, Biron P et al (2012) Autologous stem-cell transplantation in patients with mantle cell lymphoma beyond 65 years of age: a study from the European Group for Blood and Marrow Transplantation (EBMT). Ann Oncol 23(1):166\u2013171","journal-title":"Ann Oncol"},{"issue":"13","key":"1783_CR91","doi-asserted-by":"crossref","first-page":"4003","DOI":"10.1182\/blood-2006-04-016725","volume":"108","author":"R Forstpointner","year":"2006","unstructured":"Forstpointner R, Unterhalt M, Dreyling M, Bock HP, Repp R, Wandt H, Pott C, Seymour JF et al (2006) Maintenance therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) in patients with recurring and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low Grade Lymphoma Study Group (GLSG). Blood 108(13):4003\u20134008","journal-title":"Blood"},{"issue":"9","key":"1783_CR92","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1093\/annonc\/mdl127","volume":"17","author":"BS Kahl","year":"2006","unstructured":"Kahl BS, Longo WL, Eickhoff JC, Zehnder J, Jones C, Blank J, McFarland T, Bottner W et al (2006) Maintenance rituximab following induction chemoimmunotherapy may prolong progression-free survival in mantle cell lymphoma: a pilot study from the Wisconsin Oncology Network. Ann Oncol 17(9):1418\u20131423","journal-title":"Ann Oncol"},{"issue":"15S","key":"1783_CR93","first-page":"e19510","volume":"27","author":"W Jurczak","year":"2009","unstructured":"Jurczak W, Giza A, Krochmalczyk D, Sobocinski M, Zimowska-Curylo D, Stella-Holowiecka B, Boguradzki P, Kisiel E et al (2009) Survival benefit of post induction consolidation therapy in MCL (mantle cell lymphoma): a Polish Lymphoma Research Group (PLRG) retrospective multicenter analysis. ASCO Meeting Abstracts 27(15S):e19510","journal-title":"ASCO Meeting Abstracts"},{"key":"1783_CR94","doi-asserted-by":"crossref","unstructured":"Smith MR, Zhang L, Gordon LI, Foran J, Kahl B, Gascoyne RD, Advani R, Paietta E et al. (2007) Phase II study of R-CHOP followed by 90Y-ibritumomab tiuxetan in untreated mantle cell lymphoma: Eastern Cooperative Oncology Group Study E1499. Blood 110 (11 ASH Annual Meeting Abstracts):389","DOI":"10.1182\/blood.V110.11.389.389"},{"key":"1783_CR95","doi-asserted-by":"crossref","unstructured":"Arranz R, Garcia-Noblejas A, Grande C, Terol J, Sanchez JJ, Perez-Calvo J, Canales M, Garcia-Marco JA et al. (2009) Feasability and toxicity after induction treatment with rituximab-HCVAD and metotrexate\/citarabine, followed by consolidation with Y-90 ibritumomab tiuxetan (phase II GELTAMO-LCM 04\u201302 study). Blood 114 (22 ASH Annual Meeting Abstracts):1703","DOI":"10.1182\/blood.V114.22.1703.1703"},{"key":"1783_CR96","unstructured":"Kolstad A, Laurell A, Andersen NS, Elonen E, Raty R, Pedersen LB, Loft A, Bogsrud TV et al. (2009) 90y-Ibritumumab Tiuxetan (Zevalin (R))-BEAM\/C with autologous stem cell support as frontline therapy for advanced mantle cell lymphoma. Preliminary results from the Third Nordic MCL Phase II Study (MCL3). Blood 114 (22 ASH Annual Meeting Abstracts):932"},{"issue":"8","key":"1783_CR97","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.3324\/haematol.2009.011759","volume":"95","author":"R Gressin","year":"2010","unstructured":"Gressin R, Caulet-Maugendre S, Deconinck E, Tournilhac O, Gyan E, Moles MP, El Yamani A, Cornillon J et al (2010) Evaluation of the (R)VAD+C regimen for the treatment of newly diagnosed mantle cell lymphoma. Combined results of two prospective phase II trials from the French GOELAMS group. Haematologica 95(8):1350\u20131357","journal-title":"Haematologica"},{"issue":"3","key":"1783_CR98","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3109\/10428194.2010.534518","volume":"52","author":"S Sachanas","year":"2011","unstructured":"Sachanas S, Pangalis GA, Vassilakopoulos TP, Korkolopoulou P, Kontopidou FN, Athanasoulia M, Yiakoumis X, Kalpadakis C et al (2011) Combination of rituximab with chlorambucil as first line treatment in patients with mantle cell lymphoma: a highly effective regimen. Leuk Lymphoma 52(3):387\u2013393","journal-title":"Leuk Lymphoma"},{"key":"1783_CR99","unstructured":"Rummel MJ, Kaiser U, Balser C, Stauch MB, Brugger W, Welslau M, Niederle N, Losem C et al. (2010) Bendamustine plus rituximab versus fludarabine plus rituximab in patients with relapsed follicular, indolent and mantle cell lymphomas. Final results of the Randomized Phase III Study NHL 2\u20132003 on Behalf of the StiL (Study Group Indolent Lymphomas, Germany). Blood 116 (21 ASH Annual Meeting Abstracts):856"},{"issue":"7","key":"1783_CR100","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.3324\/haematol.2011.041392","volume":"96","author":"W Lamm","year":"2011","unstructured":"Lamm W, Kaufmann H, Raderer M, Hoffmann M, Chott A, Zielinski C, Drach J (2011) Bortezomib combined with rituximab and dexamethasone is an active regimen for patients with relapsed and chemotherapy-refractory mantle cell lymphoma. Haematologica 96(7):1008\u20131014","journal-title":"Haematologica"},{"issue":"10","key":"1783_CR101","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1002\/cncr.23880","volume":"113","author":"M Wang","year":"2008","unstructured":"Wang M, Fayad L, Cabanillas F, Hagemeister F, McLaughlin P, Rodriguez MA, Kwak LW, Zhou Y et al (2008) Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma. Cancer 113(10):2734\u20132741","journal-title":"Cancer"},{"issue":"6","key":"1783_CR102","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1080\/10428190801993470","volume":"49","author":"TE Witzig","year":"2008","unstructured":"Witzig TE, Geyer SM, Kurtin PJ, Colgan JP, Inwards DJ, Micallef IN, LaPlant BR, Michalak JC et al (2008) Salvage chemotherapy with rituximab DHAP for relapsed non-Hodgkin lymphoma: a phase II trial in the North Central Cancer Treatment Group. Leuk Lymphoma 49(6):1074\u20131080","journal-title":"Leuk Lymphoma"},{"issue":"27","key":"1783_CR103","doi-asserted-by":"crossref","first-page":"4473","DOI":"10.1200\/JCO.2008.17.0001","volume":"26","author":"KS Robinson","year":"2008","unstructured":"Robinson KS, Williams ME, van der Jagt RH, Cohen P, Herst JA, Tulpule A, Schwartzberg LS, Lemieux B et al (2008) Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin\u2019s lymphoma. J Clin Oncol 26(27):4473\u20134479","journal-title":"J Clin Oncol"},{"issue":"7","key":"1783_CR104","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1080\/10428190701361828","volume":"48","author":"R Weide","year":"2007","unstructured":"Weide R, Hess G, Koppler H, Heymanns J, Thomalla J, Aldaoud A, Losem C, Schmitz S et al (2007) High anti-lymphoma activity of bendamustine\/mitoxantrone\/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG). Leuk Lymphoma 48(7):1299\u20131306","journal-title":"Leuk Lymphoma"},{"issue":"6","key":"1783_CR105","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1517\/14656566.2.6.929","volume":"2","author":"SA Johnson","year":"2001","unstructured":"Johnson SA (2001) Nucleoside analogues in the treatment of haematological malignancies. Expert Opin Pharmacother 2(6):929\u2013943","journal-title":"Expert Opin Pharmacother"},{"issue":"5 Suppl 10","key":"1783_CR106","first-page":"16","volume":"23","author":"GJ Peters","year":"1996","unstructured":"Peters GJ, Ruiz van Haperen VW, Bergman AM, Veerman G, Smitskamp-Wilms E, van Moorsel CJ, Kuiper CM, Braakhuis BJ (1996) Preclinical combination therapy with gemcitabine and mechanisms of resistance. Semin Oncol 23(5 Suppl 10):16\u201324","journal-title":"Semin Oncol"},{"issue":"2","key":"1783_CR107","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1093\/annonc\/mdl395","volume":"18","author":"F Morschhauser","year":"2007","unstructured":"Morschhauser F, Depil S, Jourdan E, Wetterwald M, Bouabdallah R, Marit G, Solal-C\u00e9ligny P, Sebban C et al (2007) Phase II study of gemcitabine-dexamethasone with or without cisplatin in relapsed or refractory mantle cell lymphoma. Ann Oncol 18(2):370\u2013375","journal-title":"Ann Oncol"},{"key":"1783_CR108","doi-asserted-by":"crossref","unstructured":"Gironella M, Lopez MDA, Pau A, Anny J, Noelia P, Bosch F (2010) Rituximab plus gemcitabine and oxaliplatin as salvage therapy in patients with relapsed\/refractory mantle-cell lymphoma. Blood 116 (21 ASH Annual Meeting Abstracts):2825","DOI":"10.1182\/blood.V116.21.2825.2825"},{"issue":"11","key":"1783_CR109","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1080\/10428190701618268","volume":"48","author":"J Rodr\u00edguez","year":"2007","unstructured":"Rodr\u00edguez J, Gutierrez A, Palacios A, Navarrete M, Blancas I, Alarcon J, Caballero MD, De Mattos SF et al (2007) Rituximab, gemcitabine and oxaliplatin: an effective regimen in patients with refractory and relapsing mantle cell lymphoma. Leuk Lymphoma 48(11):2172\u20132178","journal-title":"Leuk Lymphoma"},{"issue":"5","key":"1783_CR110","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1007\/s10637-008-9191-7","volume":"27","author":"LE Garbo","year":"2009","unstructured":"Garbo LE, Flynn PJ, MacRae MA, Rauch MA, Wang Y, Kolibaba KS (2009) Results of a phase II trial of gemcitabine, mitoxantrone, and rituximab in relapsed or refractory mantle cell lymphoma. Invest New Drugs 27(5):476\u2013481","journal-title":"Invest New Drugs"},{"issue":"9","key":"1783_CR111","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1002\/cncr.25756","volume":"117","author":"S Dietrich","year":"2011","unstructured":"Dietrich S, Tielesch B, Rieger M, Nickelsen M, Pott C, Witzens-Harig M, Kneba M, Schmitz N et al (2011) Patterns and outcome of relapse after autologous stem cell transplantation for mantle cell lymphoma. Cancer 117(9):1901\u20131910","journal-title":"Cancer"},{"issue":"1","key":"1783_CR112","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1200\/JCO.1998.16.1.13","volume":"16","author":"AS Freedman","year":"1998","unstructured":"Freedman AS, Neuberg D, Gribben JG, Mauch P, Soiffer RJ, Fisher DC, Anderson KC, Andersen N et al (1998) High-dose chemoradiotherapy and anti-B-cell monoclonal antibody-purged autologous bone marrow transplantation in mantle-cell lymphoma: no evidence for long-term remission. J Clin Oncol 16(1):13\u201318","journal-title":"J Clin Oncol"},{"issue":"5","key":"1783_CR113","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1046\/j.1365-2141.2003.04140.x","volume":"120","author":"E Vandenberghe","year":"2003","unstructured":"Vandenberghe E, Ruiz de Elvira C, Loberiza FR, Conde E, Lopez-Guillermo A, Gisselbrecht C, Guilhot F, Vose JM et al (2003) Outcome of autologous transplantation for mantle cell lymphoma: a study by the European Blood and Bone Marrow Transplant and Autologous Blood and Marrow Transplant Registries. Br J Haematol 120(5):793\u2013800","journal-title":"Br J Haematol"},{"issue":"7","key":"1783_CR114","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/sj.bmt.1701400","volume":"22","author":"N Milpied","year":"1998","unstructured":"Milpied N, Gaillard F, Moreau P, Mahe B, Souchet J, Rapp MJ, Bulabois CE, Morineau N et al (1998) High-dose therapy with stem cell transplantation for mantle cell lymphoma: results and prognostic factors, a single center experience. Bone Marrow Transplant 22(7):645\u2013650","journal-title":"Bone Marrow Transplant"},{"issue":"6","key":"1783_CR115","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S1083-8791(00)70030-9","volume":"6","author":"JM Vose","year":"2000","unstructured":"Vose JM, Bierman PJ, Weisenburger DD, Lynch JC, Bociek Y, Chan WC, Greiner TC, Armitage JO (2000) Autologous hematopoietic stem cell transplantation for mantle cell lymphoma. Biol Blood Marrow Transplant 6(6):640\u2013645","journal-title":"Biol Blood Marrow Transplant"},{"issue":"5","key":"1783_CR116","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3816\/CLML.2010.n.066","volume":"10","author":"ME Williams","year":"2010","unstructured":"Williams ME, Dreyling M, Winter J, Muneer S, Leonard JP (2010) Management of mantle cell lymphoma: key challenges and next steps. Clin Lymphoma Myeloma Leuk 10(5):336\u2013346","journal-title":"Clin Lymphoma Myeloma Leuk"},{"issue":"1","key":"1783_CR117","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1200\/JCO.2007.11.9248","volume":"26","author":"A Krishnan","year":"2008","unstructured":"Krishnan A, Nademanee A, Fung HC, Raubitschek AA, Molina A, Yamauchi D, Rodriguez R, Spielberger RT et al (2008) Phase II trial of a transplantation regimen of yttrium-90 ibritumomab tiuxetan and high-dose chemotherapy in patients with non-Hodgkin\u2019s lymphoma. J Clin Oncol 26(1):90\u201395","journal-title":"J Clin Oncol"},{"issue":"9","key":"1783_CR118","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1182\/blood.V99.9.3158","volume":"99","author":"AK Gopal","year":"2002","unstructured":"Gopal AK, Rajendran JG, Petersdorf SH, Maloney DG, Eary JF, Wood BL, Gooley TA, Bush SA et al (2002) High-dose chemo-radioimmunotherapy with autologous stem cell support for relapsed mantle cell lymphoma. Blood 99(9):3158\u20133162","journal-title":"Blood"},{"issue":"23","key":"1783_CR119","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1200\/JCO.2003.05.501","volume":"21","author":"IF Khouri","year":"2003","unstructured":"Khouri IF, Lee MS, Saliba RM, Jun G, Fayad L, Younes A, Pro B, Acholonu S et al (2003) Nonablative allogeneic stem-cell transplantation for advanced\/recurrent mantle-cell lymphoma. J Clin Oncol 21(23):4407\u20134412","journal-title":"J Clin Oncol"},{"issue":"10","key":"1783_CR120","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.bbmt.2010.04.006","volume":"16","author":"G Cook","year":"2010","unstructured":"Cook G, Smith GM, Kirkland K, Lee J, Pearce R, Thomson K, Morris E, Orchard K et al (2010) Outcome following reduced-intensity allogeneic stem cell transplantation (RIC AlloSCT) for relapsed and refractory mantle cell lymphoma (MCL): a study of the British Society for Blood and Marrow Transplantation. Biol Blood Marrow Transplant 16(10):1419\u20131427","journal-title":"Biol Blood Marrow Transplant"},{"issue":"11","key":"1783_CR121","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1038\/sj.leu.2404822","volume":"21","author":"P Corradini","year":"2007","unstructured":"Corradini P, Dodero A, Farina L, Fanin R, Patriarca F, Miceli R, Matteucci P, Bregni M et al (2007) Allogeneic stem cell transplantation following reduced-intensity conditioning can induce durable clinical and molecular remissions in relapsed lymphomas: pre-transplant disease status and histotype heavily influence outcome. Leukemia 21(11):2316\u20132323","journal-title":"Leukemia"},{"issue":"12","key":"1783_CR122","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1182\/blood-2004-06-2275","volume":"104","author":"MB Maris","year":"2004","unstructured":"Maris MB, Sandmaier BM, Storer BE, Chauncey T, Stuart MJ, Maziarz RT, Agura E, Langston AA et al (2004) Allogeneic hematopoietic cell transplantation after fludarabine and 2 Gy total body irradiation for relapsed and refractory mantle cell lymphoma. Blood 104(12):3535\u20133542","journal-title":"Blood"},{"issue":"13","key":"1783_CR123","doi-asserted-by":"crossref","first-page":"4310","DOI":"10.1182\/blood-2001-11-0107","volume":"100","author":"SP Robinson","year":"2002","unstructured":"Robinson SP, Goldstone AH, Mackinnon S, Carella A, Russell N, de Elvira CR, Taghipour G, Schmitz N (2002) Chemoresistant or aggressive lymphoma predicts for a poor outcome following reduced-intensity allogeneic progenitor cell transplantation: an analysis from the Lymphoma Working Party of the European Group for Blood and Bone Marrow Transplantation. Blood 100(13):4310\u20134316","journal-title":"Blood"},{"issue":"7","key":"1783_CR124","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1182\/blood-2007-03-078592","volume":"110","author":"C Kahl","year":"2007","unstructured":"Kahl C, Storer BE, Sandmaier BM, Mielcarek M, Maris MB, Blume KG, Niederwieser D, Chauncey TR et al (2007) Relapse risk in patients with malignant diseases given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. Blood 110(7):2744\u20132748","journal-title":"Blood"},{"issue":"3","key":"1783_CR125","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0005-2787(72)90282-1","volume":"287","author":"M Hartmann","year":"1972","unstructured":"Hartmann M, Zimmer C (1972) Investigation of cross-link formation in DNA by the alkylating cytostatic IMET 3106, 3393 and 3943. Biochim Biophys Acta 287(3):386\u2013389","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"1783_CR126","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1158\/1078-0432.CCR-07-1061","volume":"14","author":"LM Leoni","year":"2008","unstructured":"Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Niemeyer CC (2008) Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res 14(1):309\u2013317","journal-title":"Clin Cancer Res"},{"key":"1783_CR127","doi-asserted-by":"crossref","unstructured":"Ogura M, Uchida T, Ando K, Ohmachi K, Itoh K, Kubota N, Ishizawa K, Yamamoto J et al. (2009) Bendamustine Is highly effective for relapsed or refractory indolent b-cell non-hodgkin lymphoma (B-NHL) and mantle cell lymphoma (MCL): final results of a Japanese Multicenter Phase II Study. Blood 114 (22 ASH Annual Meeting Abstracts):3694","DOI":"10.1182\/blood.V114.22.3694.3694"},{"issue":"3","key":"1783_CR128","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1365-2141.2005.05777.x","volume":"131","author":"D Bauwens","year":"2005","unstructured":"Bauwens D, Maerevoet M, Michaux L, Theate I, Hagemeijer A, Stul M, Danse E, Costantini S et al (2005) Activity and safety of combined rituximab with chlorambucil in patients with mantle cell lymphoma. Br J Haematol 131(3):338\u2013340","journal-title":"Br J Haematol"},{"issue":"5","key":"1783_CR129","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1200\/JCO.1998.16.5.1922","volume":"16","author":"W Hiddemann","year":"1998","unstructured":"Hiddemann W, Unterhalt M, Herrmann R, Woltjen HH, Kreuser ED, Trumper L, Reuss-Borst M, Terhardt-Kasten E et al (1998) Mantle-cell lymphomas have more widespread disease and a slower response to chemotherapy compared with follicle-center lymphomas: results of a prospective comparative analysis of the German Low-Grade Lymphoma Study Group. J Clin Oncol 16(5):1922\u20131930","journal-title":"J Clin Oncol"},{"issue":"5","key":"1783_CR130","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1097\/00001622-200109000-00005","volume":"13","author":"JP Leonard","year":"2001","unstructured":"Leonard JP, Schattner EJ, Coleman M (2001) Biology and management of mantle cell lymphoma. Curr Opin Oncol 13(5):342\u2013347","journal-title":"Curr Opin Oncol"},{"issue":"5","key":"1783_CR131","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/01.cco.0000174039.69656.2b","volume":"17","author":"ME Williams","year":"2005","unstructured":"Williams ME, Densmore JJ (2005) Biology and therapy of mantle cell lymphoma. Curr Opin Oncol 17(5):425\u2013431","journal-title":"Curr Opin Oncol"},{"issue":"3","key":"1783_CR132","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/cncr.23580","volume":"113","author":"SM Ansell","year":"2008","unstructured":"Ansell SM, Inwards DJ, Rowland KM Jr, Flynn PJ, Morton RF, Moore DF Jr, Kaufmann SH, Ghobrial I et al (2008) Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. Cancer 113(3):508\u2013514","journal-title":"Cancer"},{"issue":"23","key":"1783_CR133","doi-asserted-by":"crossref","first-page":"5347","DOI":"10.1200\/JCO.2005.13.466","volume":"23","author":"TE Witzig","year":"2005","unstructured":"Witzig TE, Geyer SM, Ghobrial I, Inwards DJ, Fonseca R, Kurtin P, Ansell SM, Luyun R et al (2005) Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. J Clin Oncol 23(23):5347\u20135356","journal-title":"J Clin Oncol"},{"issue":"23","key":"1783_CR134","doi-asserted-by":"crossref","first-page":"3822","DOI":"10.1200\/JCO.2008.20.7977","volume":"27","author":"G Hess","year":"2009","unstructured":"Hess G, Herbrecht R, Romaguera J, Verhoef G, Crump M, Gisselbrecht C, Laurell A, Offner F et al (2009) Phase III study to evaluate temsirolimus compared with investigator\u2019s choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol 27(23):3822\u20133829","journal-title":"J Clin Oncol"},{"issue":"30","key":"1783_CR135","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.1200\/JCO.2006.07.9665","volume":"24","author":"RI Fisher","year":"2006","unstructured":"Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A et al (2006) Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 24(30):4867\u20134874","journal-title":"J Clin Oncol"},{"issue":"3","key":"1783_CR136","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/annonc\/mdn656","volume":"20","author":"A Goy","year":"2009","unstructured":"Goy A, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A et al (2009) Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol 20(3):520\u2013525","journal-title":"Ann Oncol"},{"issue":"4","key":"1783_CR137","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1470-2045(11)70062-6","volume":"12","author":"SM Ansell","year":"2011","unstructured":"Ansell SM, Tang H, Kurtin PJ, Koenig PA, Inwards DJ, Shah K, Ziesmer SC, Feldman AL et al (2011) Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study. The Lancet Oncology 12(4):361\u2013368","journal-title":"The Lancet Oncology"},{"issue":"6","key":"1783_CR138","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1200\/JCO.2010.31.1142","volume":"29","author":"J Ruan","year":"2011","unstructured":"Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM, Lacasce A, Morrison J et al (2011) Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. J Clin Oncol 29(6):690\u2013697","journal-title":"J Clin Oncol"},{"issue":"1","key":"1783_CR139","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1365-2141.2010.08315.x","volume":"151","author":"JE Romaguera","year":"2010","unstructured":"Romaguera JE, Fayad LE, McLaughlin P, Pro B, Rodriguez A, Wang M, Weaver P, Hartig K et al (2010) Phase I trial of bortezomib in combination with rituximab-HyperCVAD alternating with rituximab, methotrexate and cytarabine for untreated aggressive mantle cell lymphoma. Br J Haematol 151(1):47\u201353","journal-title":"Br J Haematol"},{"key":"1783_CR140","doi-asserted-by":"crossref","unstructured":"Wang M, Rule SA, Martin P, Goy A, Auer R, Kahl BS, Jurczak W, Advani RH et al. (2012) Interim results of an international, multicenter, phase 2 study of Bruton\u2019s tyrosine kinase (BTK) inhibitor, ibrutinib (PCI-32765), in relapsed or refractory mantle cell lymphoma (MCL): durable efficacy and tolerability with longer follow-up. Blood 120 (21 ASH Annual Meeting Abstracts):904","DOI":"10.1182\/blood.V120.21.904.904"},{"issue":"2","key":"1783_CR141","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/leu.2010.226","volume":"25","author":"TE Witzig","year":"2011","unstructured":"Witzig TE, Reeder CB, LaPlant BR, Gupta M, Johnston PB, Micallef IN, Porrata LF, Ansell SM et al (2011) A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma. Leukemia 25(2):341\u2013347","journal-title":"Leukemia"},{"issue":"5","key":"1783_CR142","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nrc1362","volume":"4","author":"MA Bjornsti","year":"2004","unstructured":"Bjornsti MA, Houghton PJ (2004) The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4(5):335\u2013348","journal-title":"Nat Rev Cancer"},{"key":"1783_CR143","unstructured":"Temsirolimus: CCI 779, CCI-779, cell cycle inhibitor-779 (2004). Drugs R D 5(6):363\u2013367"},{"issue":"11","key":"1783_CR144","doi-asserted-by":"crossref","first-page":"5549","DOI":"10.1158\/0008-5472.CAN-05-2825","volume":"66","author":"D Bufalo Del","year":"2006","unstructured":"Del Bufalo D, Ciuffreda L, Trisciuoglio D, Desideri M, Cognetti F, Zupi G, Milella M (2006) Antiangiogenic potential of the mammalian target of rapamycin inhibitor temsirolimus. Cancer Res 66(11):5549\u20135554","journal-title":"Cancer Res"},{"key":"1783_CR145","doi-asserted-by":"crossref","unstructured":"Hess G, Kang L, Moran PJ (2011) Effect of prognostic risk classification on temsirolimus efficacy and safety outcomes in patients with relapsed\/refractory mantle cell lymphoma. Blood 2011 (21 ASH annual meeting abstracts):2708","DOI":"10.1182\/blood.V118.21.2708.2708"},{"key":"1783_CR146","doi-asserted-by":"crossref","unstructured":"Hess G, Keller U, Atta J, Buske C, Borchmann P, Medler C, Witzens-Harig M, Dreyling MH (2011) Temsirolimus in combination with bendamustine and rituximab for the treatment of relapsed mantle cell and follicular lymphoma: report on an ongoing phase I\/II trial. Blood 118 (21 ASH Annual meeting abstracts):623","DOI":"10.1182\/blood.V118.21.2697.2697"},{"issue":"2","key":"1783_CR147","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1158\/0008-5472.CAN-06-2317","volume":"67","author":"D Verhelle","year":"2007","unstructured":"Verhelle D, Corral LG, Wong K, Mueller JH, Moutouh-de Parseval L, Jensen-Pergakes K, Schafer PH, Chen R et al (2007) Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells. Cancer Res 67(2):746\u2013755","journal-title":"Cancer Res"},{"issue":"9","key":"1783_CR148","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1182\/blood.V96.9.2943","volume":"96","author":"T Hideshima","year":"2000","unstructured":"Hideshima T, Chauhan D, Shima Y, Raje N, Davies FE, Tai YT, Treon SP, Lin B et al (2000) Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 96(9):2943\u20132950","journal-title":"Blood"},{"issue":"2","key":"1783_CR149","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.mvr.2008.08.003","volume":"77","author":"L Lu","year":"2009","unstructured":"Lu L, Payvandi F, Wu L, Zhang LH, Hariri RJ, Man HW, Chen RS, Muller GW et al (2009) The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions. Microvasc Res 77(2):78\u201386","journal-title":"Microvasc Res"},{"issue":"2","key":"1783_CR150","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1182\/blood-2005-10-4184","volume":"108","author":"DH Chang","year":"2006","unstructured":"Chang DH, Liu N, Klimek V, Hassoun H, Mazumder A, Nimer SD, Jagannath S, Dhodapkar MV (2006) Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications. Blood 108(2):618\u2013621","journal-title":"Blood"},{"issue":"7","key":"1783_CR151","first-page":"2427","volume":"118","author":"AG Ramsay","year":"2008","unstructured":"Ramsay AG, Johnson AJ, Lee AM, Gorgun G, Le Dieu R, Blum W, Byrd JC, Gribben JG (2008) Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J Clin Invest 118(7):2427\u20132437","journal-title":"J Clin Invest"},{"issue":"21","key":"1783_CR152","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1056\/NEJMoa070594","volume":"357","author":"M Dimopoulos","year":"2007","unstructured":"Dimopoulos M, Spencer A, Attal M, Prince HM, Harousseau JL, Dmoszynska A, San Miguel J, Hellmann A et al (2007) Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med 357(21):2123\u20132132","journal-title":"N Engl J Med"},{"issue":"30","key":"1783_CR153","doi-asserted-by":"crossref","first-page":"4952","DOI":"10.1200\/JCO.2007.15.3429","volume":"26","author":"PH Wiernik","year":"2008","unstructured":"Wiernik PH, Lossos IS, Tuscano JM, Justice G, Vose JM, Cole CE, Lam W, McBride K et al (2008) Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin\u2019s lymphoma. J Clin Oncol 26(30):4952\u20134957","journal-title":"J Clin Oncol"},{"issue":"3","key":"1783_CR154","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-2141.2009.07626.x","volume":"145","author":"TM Habermann","year":"2009","unstructured":"Habermann TM, Lossos IS, Justice G, Vose JM, Wiernik PH, McBride K, Wride K, Ervin-Haynes A et al (2009) Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma. Br J Haematol 145(3):344\u2013349","journal-title":"Br J Haematol"},{"issue":"3","key":"1783_CR155","doi-asserted-by":"crossref","first-page":"416","DOI":"10.3324\/haematol.2011.051813","volume":"97","author":"F Zaja","year":"2012","unstructured":"Zaja F, De Luca S, Vitolo U, Orsucci L, Levis A, Salvi F, Rusconi C, Ravelli E et al (2012) Salvage treatment with lenalidomide and dexamethasone in relapsed\/refractory mantle cell lymphoma: clinical results and effects on microenvironment and neo-angiogenic biomarkers. Haematologica 97(3):416\u2013422","journal-title":"Haematologica"},{"issue":"1","key":"1783_CR156","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4049\/jimmunol.171.1.88","volume":"171","author":"LV Pham","year":"2003","unstructured":"Pham LV, Tamayo AT, Yoshimura LC, Lo P, Ford RJ (2003) Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J Immunol 171(1):88\u201395","journal-title":"J Immunol"},{"issue":"2","key":"1783_CR157","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1182\/blood.V95.2.619","volume":"95","author":"R Chiarle","year":"2000","unstructured":"Chiarle R, Budel LM, Skolnik J, Frizzera G, Chilosi M, Corato A, Pizzolo G, Magidson J et al (2000) Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma. Blood 95(2):619\u2013626","journal-title":"Blood"},{"issue":"1","key":"1783_CR158","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1182\/blood-2005-05-2091","volume":"107","author":"P Perez-Galan","year":"2006","unstructured":"Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E, Colomer D (2006) The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood 107(1):257\u2013264","journal-title":"Blood"},{"key":"1783_CR159","doi-asserted-by":"crossref","unstructured":"Kahl BS, Li H, Smith MR, Gascoyne RD, Yang DT, Paietta E, Advani RH, Horning SJ (2012) Mature results from ECOG study E1405\u2014a phase II study of VcR-CVAD with maintenance rituximab for previously untreated mantle cell lymphoma. Blood 120 (21 ASH Annual Meeting Abstracts):153","DOI":"10.1182\/blood.V120.21.153.153"},{"issue":"1 Suppl 1","key":"1783_CR160","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bbmt.2007.10.019","volume":"14","author":"P Dreger","year":"2008","unstructured":"Dreger P, Laport GG (2008) Controversies in lymphoma: the role of hematopoietic cell transplantation for mantle cell lymphoma and peripheral T cell lymphoma. Biol Blood Marrow Transplant 14(1 Suppl 1):100\u2013107","journal-title":"Biol Blood Marrow Transplant"},{"issue":"12","key":"1783_CR161","doi-asserted-by":"crossref","first-page":"2865","DOI":"10.1002\/ijc.23883","volume":"123","author":"H Brizova","year":"2008","unstructured":"Brizova H, Kalinova M, Krskova L, Mrhalova M, Kodet R (2008) Quantitative monitoring of cyclin D1 expression: a molecular marker for minimal residual disease monitoring and a predictor of the disease outcome in patients with mantle cell lymphoma. Int J Cancer 123(12):2865\u20132870","journal-title":"Int J Cancer"},{"issue":"4","key":"1783_CR162","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3324\/haematol.11267","volume":"93","author":"S B\u00f6ttcher","year":"2008","unstructured":"B\u00f6ttcher S, Ritgen M, Buske S, Gesk S, Klapper W, Hoster E, Hiddemann W, Unterhalt M et al (2008) Minimal residual disease detection in mantle cell lymphoma: methods and significance of four-color flow cytometry compared to consensus IGH-polymerase chain reaction at initial staging and for follow-up examinations. Haematologica 93(4):551\u2013559","journal-title":"Haematologica"},{"issue":"11","key":"1783_CR163","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1038\/sj.leu.2401559","volume":"13","author":"P Corradini","year":"1999","unstructured":"Corradini P, Ladetto M, Pileri A, Tarella C (1999) Clinical relevance of minimal residual disease monitoring in non-Hodgkin\u2019s lymphomas: a critical reappraisal of molecular strategies. Leukemia 13(11):1691\u20131695","journal-title":"Leukemia"},{"issue":"12","key":"1783_CR164","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1038\/sj.leu.2403202","volume":"17","author":"JJ Dongen van","year":"2003","unstructured":"van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F et al (2003) Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17(12):2257\u20132317","journal-title":"Leukemia"},{"issue":"4","key":"1783_CR165","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/sj.leu.2404586","volume":"21","author":"VH Velden van der","year":"2007","unstructured":"van der Velden VH, Cazzaniga G, Schrauder A, Hancock J, Bader P, Panzer-Grumayer ER, Flohr T, Sutton R et al (2007) Analysis of minimal residual disease by Ig\/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data. Leukemia 21(4):604\u2013611","journal-title":"Leukemia"},{"issue":"2","key":"1783_CR166","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/sj.leu.2404467","volume":"21","author":"JH Krieken van","year":"2007","unstructured":"van Krieken JH, Langerak AW, Macintyre EA, Kneba M, Hodges E, Sanz RG, Morgan GJ, Parreira A et al (2007) Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 21(2):201\u2013206","journal-title":"Leukemia"},{"issue":"5","key":"1783_CR167","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1600-0609.2012.01837.x","volume":"89","author":"KH Hamborg","year":"2012","unstructured":"Hamborg KH, Bentzen HH, Grubach L, Hokland P, Nyvold CG (2012) A highly sensitive and specific qPCR assay for quantification of the biomarker SOX11 in mantle cell lymphoma. Eur J Haematol 89(5):385\u2013394","journal-title":"Eur J Haematol"},{"issue":"2","key":"1783_CR168","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1600-0609.2008.01082.x","volume":"81","author":"M Itala","year":"2008","unstructured":"Itala M, Huhtinen AR, Juvonen V, Kairisto V, Pelliniemi TT, Penttila TL, Rauhala A, Tienhaara A et al (2008) Stem cell transplantation in poor-risk chronic lymphocytic leukemia: assessment of post-transplant minimal residual disease using four- and six-color flow cytometry and allele-specific RQ-PCR. Eur J Haematol 81(2):100\u2013106","journal-title":"Eur J Haematol"},{"issue":"8","key":"1783_CR169","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/sj.leu.2401801","volume":"14","author":"OJ Verhagen","year":"2000","unstructured":"Verhagen OJ, Willemse MJ, Breunis WB, Wijkhuijs AJ, Jacobs DC, Joosten SA, van Wering ER, van Dongen JJ et al (2000) Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia. Leukemia 14(8):1426\u20131435","journal-title":"Leukemia"},{"issue":"2","key":"1783_CR170","doi-asserted-by":"crossref","first-page":"124","DOI":"10.2174\/187152909788488627","volume":"9","author":"H Garcia-Castillo","year":"2009","unstructured":"Garcia-Castillo H, Barros-Nunez P (2009) Detection of clonal immunoglobulin and T-cell receptor gene recombination in hematological malignancies: monitoring minimal residual disease. Cardiovasc Hematol Disord Drug Targets 9(2):124\u2013135","journal-title":"Cardiovasc Hematol Disord Drug Targets"},{"issue":"5","key":"1783_CR171","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1046\/j.1365-2141.1998.00907.x","volume":"102","author":"S Pittaluga","year":"1998","unstructured":"Pittaluga S, Tierens A, Pinyol M, Campo E, Delabie J, De Wolf-Peeters C (1998) Blastic variant of mantle cell lymphoma shows a heterogenous pattern of somatic mutations of the rearranged immunoglobulin heavy chain variable genes. Br J Haematol 102(5):1301\u20131306","journal-title":"Br J Haematol"},{"issue":"2","key":"1783_CR172","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1182\/blood.V84.2.403.403","volume":"84","author":"M Hummel","year":"1994","unstructured":"Hummel M, Tamaru J, Kalvelage B, Stein H (1994) Mantle cell (previously centrocytic) lymphomas express VH genes with no or very little somatic mutations like the physiologic cells of the follicle mantle. Blood 84(2):403\u2013407","journal-title":"Blood"},{"key":"1783_CR173","first-page":"165","volume":"113","author":"D Gonzalez","year":"2005","unstructured":"Gonzalez D, Garcia-Sanz R (2005) Incomplete DJH rearrangements. Methods Mol Med 113:165\u2013173","journal-title":"Methods Mol Med"},{"issue":"10","key":"1783_CR174","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.1182\/blood.V90.10.4212","volume":"90","author":"NS Andersen","year":"1997","unstructured":"Andersen NS, Donovan JW, Borus JS, Poor CM, Neuberg D, Aster JC, Nadler LM, Freedman AS et al (1997) Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease. Blood 90(10):4212\u20134221","journal-title":"Blood"},{"issue":"8","key":"1783_CR175","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1200\/JCO.2004.10.054","volume":"22","author":"P Corradini","year":"2004","unstructured":"Corradini P, Ladetto M, Zallio F, Astolfi M, Rizzo E, Sametti S, Cuttica A, Rosato R et al (2004) Long-term follow-up of indolent lymphoma patients treated with high-dose sequential chemotherapy and autografting: evidence that durable molecular and clinical remission frequently can be attained only in follicular subtypes. J Clin Oncol 22(8):1460\u20131468","journal-title":"J Clin Oncol"},{"issue":"11","key":"1783_CR176","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/annonc\/mdh425","volume":"15","author":"W Brugger","year":"2004","unstructured":"Brugger W, Hirsch J, Grunebach F, Repp R, Brossart P, Vogel W, Kopp HG, Manz MG et al (2004) Rituximab consolidation after high-dose chemotherapy and autologous blood stem cell transplantation in follicular and mantle cell lymphoma: a prospective, multicenter phase II study. Ann Oncol 15(11):1691\u20131698","journal-title":"Ann Oncol"},{"issue":"12","key":"1783_CR177","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.bbmt.2006.07.007","volume":"12","author":"M Ladetto","year":"2006","unstructured":"Ladetto M, Magni M, Pagliano G, De Marco F, Drandi D, Ricca I, Astolfi M, Matteucci P et al (2006) Rituximab induces effective clearance of minimal residual disease in molecular relapses of mantle cell lymphoma. Biol Blood Marrow Transplant 12(12):1270\u20131276","journal-title":"Biol Blood Marrow Transplant"},{"issue":"4","key":"1783_CR178","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3324\/haematol.2011.050203","volume":"97","author":"H Liu","year":"2012","unstructured":"Liu H, Johnson JL, Koval G, Malnassy G, Sher D, Damon LE, Hsi ED, Bucci DM et al (2012) Detection of minimal residual disease following induction immunochemotherapy predicts progression free survival in mantle cell lymphoma: final results of CALGB 59909. Haematologica 97(4):579\u2013585","journal-title":"Haematologica"},{"issue":"26","key":"1783_CR179","doi-asserted-by":"crossref","first-page":"4365","DOI":"10.1200\/JCO.2008.21.3116","volume":"27","author":"NS Andersen","year":"2009","unstructured":"Andersen NS, Pedersen LB, Laurell A, Elonen E, Kolstad A, Boesen AM, Pedersen LM, Lauritzsen GF et al (2009) Pre-emptive treatment with rituximab of molecular relapse after autologous stem cell transplantation in mantle cell lymphoma. J Clin Oncol 27(26):4365\u20134370","journal-title":"J Clin Oncol"},{"issue":"6","key":"1783_CR180","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/sj.leu.2402922","volume":"17","author":"VH Velden van der","year":"2003","unstructured":"van der Velden VH, Hochhaus A, Cazzaniga G, Szczepanski T, Gabert J, van Dongen JJ (2003) Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia 17(6):1013\u20131034","journal-title":"Leukemia"},{"issue":"12","key":"1783_CR181","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1038\/leu.2008.121","volume":"22","author":"R Sutton","year":"2008","unstructured":"Sutton R, Bahar AY, Kwan E, Giles JE, Venn NC, Tran S, Hackenberg N, Pozza LD et al (2008) Improving minimal residual disease detection in precursor B-ALL based on immunoglobulin-kappa and heavy-chain gene rearrangements. Leukemia 22(12):2265\u20132267","journal-title":"Leukemia"},{"issue":"8","key":"1783_CR182","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1038\/sj.leu.2402584","volume":"16","author":"ML Sanchez","year":"2002","unstructured":"Sanchez ML, Almeida J, Vidriales B, Lopez-Berges MC, Garcia-Marcos MA, Moro MJ, Corrales A, Calmuntia MJ et al (2002) Incidence of phenotypic aberrations in a series of 467 patients with B chronic lymphoproliferative disorders: basis for the design of specific four-color stainings to be used for minimal residual disease investigation. Leukemia 16(8):1460\u20131469","journal-title":"Leukemia"},{"issue":"12","key":"1783_CR183","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1002\/cyto.a.20638","volume":"73A","author":"CE Pedreira","year":"2008","unstructured":"Pedreira CE, Costa ES, Almeida J, Fernandez C, Quijano S, Flores J, Barrena S, Lecrevisse Q et al (2008) A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferative disorders. Cytometry A 73A(12):1141\u20131150","journal-title":"Cytometry A"},{"issue":"7","key":"1783_CR184","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S1470-2045(00)00418-6","volume":"2","author":"T Szczepanski","year":"2001","unstructured":"Szczepanski T, Orfao A, van der Velden VH, San Miguel JF, van Dongen JJ (2001) Minimal residual disease in leukaemia patients. Lancet Oncol 2(7):409\u2013417","journal-title":"Lancet Oncol"},{"issue":"9","key":"1783_CR185","first-page":"1899","volume":"26","author":"JJ Dongen van","year":"2012","unstructured":"van Dongen JJ, Orfao A (2012) EuroFlow: resetting leukemia and lymphoma immunophenotyping. Basis for companion diagnostics and personalized medicine Leukemia 26(9):1899\u20131907","journal-title":"Basis for companion diagnostics and personalized medicine. Leukemia"},{"issue":"9","key":"1783_CR186","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1038\/leu.2012.120","volume":"26","author":"JJ Dongen van","year":"2012","unstructured":"van Dongen JJ, Lhermitte L, Bottcher S, Almeida J, van der Velden VH, Flores-Montero J, Rawstron A, Asnafi V et al (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26(9):1908\u20131975","journal-title":"Leukemia"},{"issue":"11","key":"1783_CR187","first-page":"2819","volume":"13","author":"I Teodorovic","year":"1995","unstructured":"Teodorovic I, Pittaluga S, Kluin-Nelemans JC, Meerwaldt JH, Hagenbeek A, van Glabbeke M, Somers R, Bijnens L et al (1995) Efficacy of four different regimens in 64 mantle-cell lymphoma cases: clinicopathologic comparison with 498 other non-Hodgkin\u2019s lymphoma subtypes. European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group J Clin Oncol 13(11):2819\u20132826","journal-title":"European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group. J Clin Oncol"},{"issue":"5","key":"1783_CR188","first-page":"836","volume":"10","author":"M Unterhalt","year":"1996","unstructured":"Unterhalt M, Herrmann R, Tiemann M, Parwaresch R, Stein H, Trumper L, Nahler M, Reuss-Borst M et al (1996) Prednimustine, mitoxantrone (PmM) vs cyclophosphamide, vincristine, prednisone (COP) for the treatment of advanced low-grade non-Hodgkin\u2019s lymphoma. German Low-Grade Lymphoma Study Group Leukemia 10(5):836\u2013843","journal-title":"German Low-Grade Lymphoma Study Group. Leukemia"},{"issue":"5","key":"1783_CR189","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1002\/cncr.22093","volume":"107","author":"C Nickenig","year":"2006","unstructured":"Nickenig C, Dreyling M, Hoster E, Pfreundschuh M, Trumper L, Reiser M, Wandt H, Lengfelder E et al (2006) Combined cyclophosphamide, vincristine, doxorubicin, and prednisone (CHOP) improves response rates but not survival and has lower hematologic toxicity compared with combined mitoxantrone, chlorambucil, and prednisone (MCP) in follicular and mantle cell lymphomas: results of a prospective randomized trial of the German Low-Grade Lymphoma Study Group. Cancer 107(5):1014\u20131022","journal-title":"Cancer"},{"issue":"2","key":"1783_CR190","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00277-002-0581-1","volume":"82","author":"M Herold","year":"2003","unstructured":"Herold M, Dolken G, Fiedler F, Franke A, Freund M, Helbig W, Pasold R (2003) Randomized phase III study for the treatment of advanced indolent non-Hodgkin\u2019s lymphomas (NHL) and mantle cell lymphoma: chemotherapy versus chemotherapy plus rituximab. Ann Hematol 82(2):77\u201379","journal-title":"Ann Hematol"},{"issue":"12","key":"1783_CR191","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.1200\/JCO.1998.16.12.3803","volume":"16","author":"IF Khouri","year":"1998","unstructured":"Khouri IF, Romaguera J, Kantarjian H, Palmer JL, Pugh WC, Korbling M, Hagemeister F, Samuels B et al (1998) Hyper-CVAD and high-dose methotrexate\/cytarabine followed by stem-cell transplantation: an active regimen for aggressive mantle-cell lymphoma. J Clin Oncol 16(12):3803\u20133809","journal-title":"J Clin Oncol"},{"issue":"1\u20132","key":"1783_CR192","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/10428190009053541","volume":"39","author":"JE Romaguera","year":"2000","unstructured":"Romaguera JE, Khouri IF, Kantarjian HM, Hagemeister FB, Rodriguez MA, McLaughlin P, Sarris AH, Younes A et al (2000) Untreated aggressive mantle cell lymphoma: results with intensive chemotherapy without stem cell transplant in elderly patients. Leuk Lymphoma 39(1\u20132):77\u201385","journal-title":"Leuk Lymphoma"},{"key":"1783_CR193","doi-asserted-by":"crossref","unstructured":"Merli F, Luminari S, Ilariucci F, Stelitano C, Petrini M, Di Renzo N, Angrilli F, Carella AM et al. (2008) Rituximab plus hypercvad alternating with high dose methotrexate and cytarabine for patients with newly diagnosed mantle cell lymphoma. A Multicenter Trial from GISL. Blood 112 (11 ASH Annual Meeting Abstracts):3050","DOI":"10.1182\/blood.V112.11.3050.3050"},{"issue":"3","key":"1783_CR194","first-page":"425","volume":"91","author":"S Guibert de","year":"2006","unstructured":"de Guibert S, Jaccard A, Bernard M, Turlure P, Bordessoule D, Lamy T (2006) Rituximab and DHAP followed by intensive therapy with autologous stem-cell transplantation as first-line therapy for mantle cell lymphoma. Haematologica 91(3):425\u2013426","journal-title":"Haematologica"},{"issue":"10","key":"1783_CR195","first-page":"1275","volume":"89","author":"F Lefr\u00e8re","year":"2004","unstructured":"Lefr\u00e8re F, Delmer A, Levy V, Delarue R, Varet B, Hermine O (2004) Sequential chemotherapy regimens followed by high-dose therapy with stem cell transplantation in mantle cell lymphoma: an update of a prospective study. Haematologica 89(10):1275\u20131276","journal-title":"Haematologica"},{"issue":"1","key":"1783_CR196","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1182\/blood-2011-09-370320","volume":"121","author":"R Delarue","year":"2013","unstructured":"Delarue R, Haioun C, Ribrag V, Brice P, Delmer A, Tilly H, Salles G, Van Hoof A et al (2013) CHOP and DHAP plus rituximab followed by autologous stem cell transplantation (ASCT) in mantle cell lymphoma (MCL): a phase II study from the GELA. Blood 121(1):48\u201353","journal-title":"Blood"},{"issue":"1","key":"1783_CR197","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3324\/haematol.10608","volume":"92","author":"P Dreger","year":"2007","unstructured":"Dreger P, Rieger M, Seyfarth B, Hensel M, Kneba M, Ho AD, Schmitz N, Pott C (2007) Rituximab-augmented myeloablation for first-line autologous stem cell transplantation for mantle cell lymphoma: effects on molecular response and clinical outcome. Haematologica 92(1):42\u201349","journal-title":"Haematologica"},{"issue":"12","key":"1783_CR198","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1002\/cncr.11838","volume":"98","author":"IF Khouri","year":"2003","unstructured":"Khouri IF, Saliba RM, Okoroji GJ, Acholonu SA, Champlin RE (2003) Long-term follow-up of autologous stem cell transplantation in patients with diffuse mantle cell lymphoma in first disease remission: the prognostic value of beta2-microglobulin and the tumor score. Cancer 98(12):2630\u20132635","journal-title":"Cancer"},{"issue":"2","key":"1783_CR199","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/annonc\/mdh069","volume":"15","author":"J Mangel","year":"2004","unstructured":"Mangel J, Leitch HA, Connors JM, Buckstein R, Imrie K, Spaner D, Crump M, Pennell N et al (2004) Intensive chemotherapy and autologous stem-cell transplantation plus rituximab is superior to conventional chemotherapy for newly diagnosed advanced stage mantle-cell lymphoma: a matched pair analysis. Ann Oncol 15(2):283\u2013290","journal-title":"Ann Oncol"},{"issue":"6","key":"1783_CR200","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/bmt.2008.349","volume":"43","author":"M Magni","year":"2009","unstructured":"Magni M, Di Nicola M, Carlo-Stella C, Matteucci P, Devizzi L, Tarella C, Benedetti F, Martelli M et al (2009) High-dose sequential chemotherapy and in vivo rituximab-purged stem cell autografting in mantle cell lymphoma: a 10-year update of the R-HDS regimen. Bone Marrow Transplant 43(6):509\u2013511","journal-title":"Bone Marrow Transplant"},{"issue":"5","key":"1783_CR201","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3109\/10428190109097721","volume":"42","author":"BJ Cohen","year":"2001","unstructured":"Cohen BJ, Moskowitz C, Straus D, Noy A, Hedrick E, Zelenetz A (2001) Cyclophosphamide\/fludarabine (CF) is active in the treatment of mantle cell lymphoma. Leuk Lymphoma 42(5):1015\u20131022","journal-title":"Leuk Lymphoma"},{"issue":"2","key":"1783_CR202","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00432-005-0023-2","volume":"132","author":"M Herold","year":"2006","unstructured":"Herold M, Schulze A, Niederwieser D, Franke A, Fricke HJ, Richter P, Freund M, Ismer B et al (2006) Bendamustine, vincristine and prednisone (BOP) versus cyclophosphamide, vincristine and prednisone (COP) in advanced indolent non-Hodgkin\u2019s lymphoma and mantle cell lymphoma: results of a randomised phase III trial (OSHO# 19). J Cancer Res Clin Oncol 132(2):105\u2013112","journal-title":"J Cancer Res Clin Oncol"},{"issue":"15","key":"1783_CR203","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.1200\/JCO.2005.08.100","volume":"23","author":"MJ Rummel","year":"2005","unstructured":"Rummel MJ, Al-Batran SE, Kim SZ, Welslau M, Hecker R, Kofahl-Krause D, Josten KM, Durk H et al (2005) Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin\u2019s lymphoma. J Clin Oncol 23(15):3383\u20133389","journal-title":"J Clin Oncol"},{"issue":"1\u20132","key":"1783_CR204","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/10428190009057644","volume":"37","author":"A Josting","year":"2000","unstructured":"Josting A, Reiser M, Wickramanayake PD, Rueffer U, Draube A, Sohngen D, Tesch H, Wolf J et al (2000) Dexa-BEAM: an effective regimen for cytoreduction prior to high-dose chemotherapy with autologous stem cell support for patients with relapsed\/refractory mantle-cell lymphoma. Leuk Lymphoma 37(1\u20132):185\u2013187","journal-title":"Leuk Lymphoma"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-013-1783-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00277-013-1783-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-013-1783-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T07:03:04Z","timestamp":1715410984000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00277-013-1783-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,29]]},"references-count":204,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["1783"],"URL":"https:\/\/doi.org\/10.1007\/s00277-013-1783-4","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,29]]}}}