{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:00:07Z","timestamp":1761541207374},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,7,27]],"date-time":"2014-07-27T00:00:00Z","timestamp":1406419200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s00277-014-2169-y","type":"journal-article","created":{"date-parts":[[2014,7,26]],"date-time":"2014-07-26T05:13:17Z","timestamp":1406351597000},"page":"145-152","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The use of anti-fibrinolytic agents in patients with HHT: a retrospective survey"],"prefix":"10.1007","volume":"94","author":[{"given":"Nusrat","family":"Zaffar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tharsha","family":"Ravichakaravarthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie E.","family":"Faughnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"Shehata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,7,27]]},"reference":[{"key":"2169_CR1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/jmg.2009.069013","volume":"48","author":"ME Faughnan","year":"2011","unstructured":"Faughnan ME, Palda VA, Garcia-Tsao G, Geisthoff UW, McDonald J, Proctor DD, Spears J, Brown DH, Buscarini E, Chesnutt MS, Cottin V, Ganguly A, Gossage JR, Guttmacher AE, Hyland RH, Kennedy SJ, Korzenik J, Mager JJ, Ozanne AP, Piccirillo JF, Picus D, Plauchu H, Porteous ME, Pyeritz RE, Ross DA, Sabba C, Swanson K, Terry P, Wallace MC, Westermann CJ, White RI, Young LH, Zarrabeitia R, HHT Foundation International Guidelines Working Group (2011) International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia. J Med Genet 48:73\u201387. doi: 10.1136\/jmg.2009.069013","journal-title":"J Med Genet"},{"key":"2169_CR2","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1051\/medsci\/20102610855","volume":"10","author":"S Bailly","year":"2010","unstructured":"Bailly S, Dupuis-Girod S, Plauchu H (2010) Rendu-Osler disease: clinical and molecular update. Med Sci (Paris) 10:855\u2013860. doi: 10.1051\/medsci\/20102610855","journal-title":"Med Sci (Paris)"},{"key":"2169_CR3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1572-0241.2003.07185.x","volume":"98","author":"AV Longacre","year":"2003","unstructured":"Longacre AV, Gross CP, Gallitelli M, Henderson KJ, White RI Jr, Proctor DD (2003) Diagnosis and management of gastrointestinal bleeding in patients with hereditary hemorrhagic telangiectasia. Am J Gastroenterol 98:59\u201365. doi: 10.1111\/j.1572-0241.2003.07185.x","journal-title":"Am J Gastroenterol"},{"key":"2169_CR4","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1007\/s11136-004-7865-y","volume":"10","author":"G Pasculli","year":"2004","unstructured":"Pasculli G, Resta F, Guastamacchia E, Di Gennaro L, Suppressa P, Sabb\u00e0 C (2004) Health-related quality of life in a rare disease: hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber disease. Qual Life Res 10:1715\u20131723. doi: 10.1007\/s11136-004-7865-y","journal-title":"Qual Life Res"},{"key":"2169_CR5","first-page":"926","volume":"12","author":"C Sabb\u00e0","year":"2001","unstructured":"Sabb\u00e0 C, Gallitelli M, Palasciano G (2001) Efficacy of unusually high doses of tranexamic acid for the treatment of epistaxis in hereditary hemorrhagic telangiectasia. CMAJ 12:926. doi: 10.1056\/NEJM200109203451216","journal-title":"CMAJ"},{"key":"2169_CR6","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1160\/TH06-07-0373","volume":"2","author":"A Fernandez-L","year":"2007","unstructured":"Fernandez-L A, Garrido-Martin EM, Sanz-Rodriguez F, Ramirez JR, Morales-Angulo C, Zarrabeitia R, Perez-Molino A, Bernab\u00e9u C, Botella LM (2007) Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): regulation of ALK-1\/endoglin pathway in endothelial cells. Thromb Haemost 2:254\u2013262. doi: 10.1160\/TH06-07-0373","journal-title":"Thromb Haemost"},{"key":"2169_CR7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.blre.2010.07.001","volume":"6","author":"CL Shovlin","year":"2010","unstructured":"Shovlin CL (2010) Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment. Blood Rev 6:203\u2013219. doi: 10.1016\/j.blre.2010.07.001","journal-title":"Blood Rev"},{"key":"2169_CR8","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1055\/s-2007-996127","volume":"23","author":"S Okamoto","year":"1997","unstructured":"Okamoto S, Hijikata-Okunomiya A, Wanaka K, Okada Y, Okamoto U (1997) Enzyme controlling medicines: introduction. Semin Thromb Hemost 23:493\u2013501. doi: 10.1055\/s-2007-996127","journal-title":"Semin Thromb Hemost"},{"key":"2169_CR9","first-page":"345","volume":"11","author":"I Roberts","year":"2012","unstructured":"Roberts I, Perel P, Prieto-Merino D, Shakur H, Coats T, Hunt BJ, Lecky F, Brohi K, Willett K, CRASH-2 Collaborators (2012) Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. BMJ 11:345. doi: 10.1136\/bmj.e5839","journal-title":"BMJ"},{"key":"2169_CR10","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1056\/NEJMoa0802395","volume":"22","author":"DA Fergusson","year":"2008","unstructured":"Fergusson DA, H\u00e9bert PC, Mazer CD, Fremes S, MacAdams C, Murkin JM, Teoh K, Duke PC, Arellano R, Blajchman MA, Bussi\u00e8res JS, C\u00f4t\u00e9 D, Karski J, Martineau R, Robblee JA, Rodger M, Wells G, Clinch J, Pretorius R (2008) A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med 22:2319\u20132331. doi: 10.1056\/NEJMoa0802395","journal-title":"N Engl J Med"},{"key":"2169_CR11","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0140-6736(10)60835-5","volume":"376","author":"The CRASH-2 Collaborators","year":"2010","unstructured":"The CRASH-2 Collaborators (2010) Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 376:23\u201332. doi: 10.1016\/S0140-6736(10)60835-5","journal-title":"Lancet"},{"key":"2169_CR12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1053\/j.jvca.2010.07.024","volume":"25","author":"K Raghunathan","year":"2011","unstructured":"Raghunathan K, Connelly NR, Kanter GJ (2011) \u03b5-Aminocaproic acid and clinical value in cardiac anesthesia. J Cardiothorac Vasc Anesth 25:16\u201319. doi: 10.1053\/j.jvca.2010.07.024","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2169_CR13","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00404-012-2624-8","volume":"287","author":"MB Sent\u00fcrk","year":"2012","unstructured":"Sent\u00fcrk MB, Cakmak Y, Yildiz G, Yildiz P (2012) Tranexamic acid for cesarean section: a double-blind, placebo-controlled, randomized clinical trial. Arch Gynecol Obstet 287:641\u2013645. doi: 10.1007\/s00404-012-2624-8","journal-title":"Arch Gynecol Obstet"},{"key":"2169_CR14","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2174\/157488612800492744","volume":"1","author":"J Ross","year":"2012","unstructured":"Ross J, Salman RA (2012) The frequency of thrombotic events among adults given antifibrinolytic drugs for spontaneous bleeding: systematic review and meta-analysis of observational studies and randomized trials. Curr Drug Saf 1:44\u201354. doi: 10.2174\/157488612800492744","journal-title":"Curr Drug Saf"},{"key":"2169_CR15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/(SICI)1096-8628(20000306)91:1<66::AID-AJMG12>3.0.CO;2-P","volume":"1","author":"CL Shovlin","year":"2000","unstructured":"Shovlin CL, Guttmacher AE, Buscarini E, Faughnan ME, Hyland RH, Westermann CJ, Kjeldsen AD, Plauchu H (2000) Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu\u2013Osler\u2013Weber syndrome). Am J Med Genet 1:66\u201367. doi: 10.1002\/(SICI)1096-8628(20000306)91:1<66::AID-AJMG12>3.0.CO;2-P","journal-title":"Am J Med Genet"},{"key":"2169_CR16","unstructured":"Dillman DA (2000) Mail and internet surveys: the tailored design method. Wiley, Wiley.com"},{"key":"2169_CR17","unstructured":"Streiner DL, Norman GR (2001) Health measurement scales: a practical guide to their development and use. Oxford Medical Publications"},{"key":"2169_CR18","volume-title":"Guide to questionnaire construction and question writing","author":"CA Woodward","year":"1986","unstructured":"Woodward CA, Chambers LW (1986) Guide to questionnaire construction and question writing. Canadian Public Health Association, Ottawa"},{"key":"2169_CR19","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1002\/lary.20818","volume":"4","author":"JB Hoag","year":"2010","unstructured":"Hoag JB, Terry P, Mitchell S, Reh D, Merlo CA (2010) An epistaxis severity score for hereditary hemorrhagic telangiectasia. Laryngoscope 4:838\u2013843. doi: 10.1002\/lary.20818","journal-title":"Laryngoscope"},{"key":"2169_CR20","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2174\/157016110791330771","volume":"4","author":"R Zarrabeitia","year":"2010","unstructured":"Zarrabeitia R, Albi\u00f1ana V, Salcedo M, Se\u00f1aris-Gonzalez B, Fernandez-Forcelledo JL, Botella LM (2010) A review on clinical management and pharmacological therapy on hereditary haemorrhagic telangiectasia (HHT). Curr Vasc Pharmacol 4:473\u2013481","journal-title":"Curr Vasc Pharmacol"},{"key":"2169_CR21","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/cc11374","volume":"3","author":"A Godier","year":"2012","unstructured":"Godier A, Roberts I, Hunt BJ (2012) Tranexamic acid: less bleeding and less thrombosis? Crit Care 3:135","journal-title":"Crit Care"},{"key":"2169_CR22","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/oxfordjournals.aje.a115129","volume":"2","author":"SD Harlow","year":"1989","unstructured":"Harlow SD, Linet MS (1989) Reference agreement between questionnaire data and medical records. The evidence for accuracy of recall. Am J Epidemiol 2:233\u2013248","journal-title":"Am J Epidemiol"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-014-2169-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00277-014-2169-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-014-2169-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T06:14:20Z","timestamp":1565676860000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00277-014-2169-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,27]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["2169"],"URL":"https:\/\/doi.org\/10.1007\/s00277-014-2169-y","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,27]]}}}