{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:20:29Z","timestamp":1790626829074,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T00:00:00Z","timestamp":1475452800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s00277-016-2818-4","type":"journal-article","created":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T22:30:36Z","timestamp":1475447436000},"page":"25-31","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":94,"title":["Expression of programmed cell death 1 and programmed cell death ligand 1 in extranodal NK\/T-cell lymphoma, nasal type"],"prefix":"10.1007","volume":"96","author":[{"given":"Jae-Cheol","family":"Jo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunsuk","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Eun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seoung Wan","family":"Chae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Jeong","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,3]]},"reference":[{"issue":"2","key":"2818_CR1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.5045\/kjh.2012.47.2.92","volume":"47","author":"J Huh","year":"2012","unstructured":"Huh J (2012) Epidemiologic overview of malignant lymphoma. Korean J Hematol 47(2):92\u2013104","journal-title":"Korean J Hematol"},{"issue":"3","key":"2818_CR2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.5045\/br.2013.48.3.171","volume":"48","author":"C Suh","year":"2013","unstructured":"Suh C, Kim WS, Kim JS, Park B-B (2013) Review of the clinical research conducted by the Consortium for Improving Survival of Lymphoma of the Korean Society of Hematology Lymphoma Working Party. Blood Res 48(3):171\u2013177","journal-title":"Blood Res"},{"key":"2818_CR3","doi-asserted-by":"publisher","unstructured":"Jaffe ES (2009) The 2008 WHO classification of lymphomas: implications for clinical practice and translational research. Hematology\/the Education Program of the American Society of Hematology American Society of Hematology Education Program: 523-531. doi: 10.1182\/asheducation-2009.1.523","DOI":"10.1182\/asheducation-2009.1.523"},{"issue":"13","key":"2818_CR4","doi-asserted-by":"publisher","first-page":"3462","DOI":"10.1158\/1078-0432.ccr-13-0855","volume":"19","author":"BJ Chen","year":"2013","unstructured":"Chen BJ, Chapuy B, Ouyang J, Sun HH, Roemer MG, Xu ML, Yu H, Fletcher CD, Freeman GJ, Shipp MA, Rodig SJ (2013) PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 19(13):3462\u20133473. doi: 10.1158\/1078-0432.ccr-13-0855","journal-title":"Clinical cancer research : an official journal of the American Association for Cancer Research"},{"issue":"6","key":"2818_CR5","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1517\/14712598.2013.770836","volume":"13","author":"O Hamid","year":"2013","unstructured":"Hamid O, Carvajal RD (2013) Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy. Expert opinion on biological therapy 13(6):847\u2013861. doi: 10.1517\/14712598.2013.770836","journal-title":"Expert opinion on biological therapy"},{"issue":"26","key":"2818_CR6","doi-asserted-by":"publisher","first-page":"2443","DOI":"10.1056\/NEJMoa1200690","volume":"366","author":"SL Topalian","year":"2012","unstructured":"Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M (2012) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. The New England journal of medicine 366(26):2443\u20132454. doi: 10.1056\/NEJMoa1200690","journal-title":"The New England journal of medicine"},{"issue":"4","key":"2818_CR7","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1056\/NEJMoa1411087","volume":"372","author":"SM Ansell","year":"2015","unstructured":"Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ, Rodig SJ, Chapuy B, Ligon AH, Zhu L, Grosso JF, Kim SY, Timmerman JM, Shipp MA, Armand P (2015) PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin\u2019s Lymphoma. New England Journal of Medicine 372(4):311\u2013319. doi: 10.1056\/NEJMoa1411087","journal-title":"New England Journal of Medicine"},{"issue":"4","key":"2818_CR8","doi-asserted-by":"publisher","first-page":"187","DOI":"10.5045\/br.2015.50.4.187","volume":"50","author":"SJ Kim","year":"2015","unstructured":"Kim SJ (2015) Consortium for Improving Survival of Lymphoma (CISL): a model of multicenter collaboration for lymphoma studies in Korea. Blood Res 50(4):187\u2013188. doi: 10.5045\/br.2015.50.4.187","journal-title":"Blood Res"},{"issue":"14","key":"2818_CR9","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1056\/nejm199309303291402","volume":"329","author":"A predictive model for aggressive non-Hodgkin\u2019s lymphoma","year":"1993","unstructured":"A predictive model for aggressive non-Hodgkin\u2019s lymphoma (1993) The International Non-Hodgkin\u2019s Lymphoma Prognostic Factors Project. The New England journal of medicine 329(14):987\u2013994. doi: 10.1056\/nejm199309303291402","journal-title":"The New England journal of medicine"},{"key":"2818_CR10","doi-asserted-by":"crossref","unstructured":"Kim SJ, Yoon DH, Jaccard A, Chng WJ, Lim ST, Hong H, Park Y, Chang KM, Maeda Y, Ishida F, Shin D-Y, Kim JS, Jeong SH, Yang D-H, Jo J-C, Lee G-W, Choi CW, Lee W-S, Chen T-Y, Kim K, Jung S-H, Murayama T, Oki Y, Advani R, d\u2019Amore F, Schmitz N, Suh C, Suzuki R, Kwong YL, Lin T-Y, Kim WS A prognostic index for natural killer cell lymphoma after non-anthracycline-based treatment: a multicentre, retrospective analysis. The Lancet Oncology 17 (3):389-400. doi:10.1016\/S1470-2045(15)00533-1","DOI":"10.1016\/S1470-2045(15)00533-1"},{"issue":"5","key":"2818_CR11","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/intimm\/8.5.765","volume":"8","author":"Y Agata","year":"1996","unstructured":"Agata Y, Kawasaki A, Nishimura H, Ishida Y, Tsubata T, Yagita H, Honjo T (1996) Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. International immunology 8(5):765\u2013772","journal-title":"International immunology"},{"issue":"13","key":"2818_CR12","doi-asserted-by":"publisher","first-page":"4232","DOI":"10.1158\/1078-0432.ccr-10-2660","volume":"17","author":"DJ Andorsky","year":"2011","unstructured":"Andorsky DJ, Yamada RE, Said J, Pinkus GS, Betting DJ, Timmerman JM (2011) Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells. Clinical cancer research : an official journal of the American Association for Cancer Research 17(13):4232\u20134244. doi: 10.1158\/1078-0432.ccr-10-2660","journal-title":"Clinical cancer research : an official journal of the American Association for Cancer Research"},{"issue":"4","key":"2818_CR13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S1470-2045(09)70096-8","volume":"10","author":"V Bouvard","year":"2009","unstructured":"Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V (2009) A review of human carcinogens\u2014Part B: biological agents. The Lancet Oncology 10(4):321\u2013322","journal-title":"The Lancet Oncology"},{"issue":"6","key":"2818_CR14","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1158\/1078-0432.ccr-11-1942","volume":"18","author":"MR Green","year":"2012","unstructured":"Green MR, Rodig S, Juszczynski P, Ouyang J, Sinha P, O\u2019Donnell E, Neuberg D, Shipp MA (2012) Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 18(6):1611\u20131618. doi: 10.1158\/1078-0432.ccr-11-1942","journal-title":"Clinical cancer research : an official journal of the American Association for Cancer Research"},{"issue":"9","key":"2818_CR15","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1007\/s00277-015-2403-2","volume":"94","author":"S Paydas","year":"2015","unstructured":"Paydas S, Bagir E, Seydaoglu G, Ercolak V, Ergin M (2015) Programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), and EBV-encoded RNA (EBER) expression in Hodgkin lymphoma. Annals of hematology 94(9):1545\u20131552. doi: 10.1007\/s00277-015-2403-2","journal-title":"Annals of hematology"},{"key":"2818_CR16","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-015-4622-5","author":"YW Koh","year":"2015","unstructured":"Koh YW, Jeon YK, Yoon DH, Suh C, Huh J (2015) Programmed death 1 expression in the peritumoral microenvironment is associated with a poorer prognosis in classical Hodgkin lymphoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. doi: 10.1007\/s13277-015-4622-5","journal-title":"Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine"},{"issue":"8","key":"2818_CR17","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.3324\/haematol.10864","volume":"92","author":"G Roncador","year":"2007","unstructured":"Roncador G, Garcia Verdes-Montenegro JF, Tedoldi S, Paterson JC, Klapper W, Ballabio E, Maestre L, Pileri S, Hansmann ML, Piris MA, Mason DY, Marafioti T (2007) Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma. Haematologica 92(8):1059\u20131066","journal-title":"Haematologica"},{"issue":"7","key":"2818_CR18","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.humpath.2005.05.008","volume":"36","author":"CM Yuan","year":"2005","unstructured":"Yuan CM, Vergilio JA, Zhao XF, Smith TK, Harris NL, Bagg A (2005) CD10 and BCL6 expression in the diagnosis of angioimmunoblastic T-cell lymphoma: utility of detecting CD10+ T cells by flow cytometry. Human pathology 36(7):784\u2013791. doi: 10.1016\/j.humpath.2005.05.008","journal-title":"Human pathology"},{"issue":"4","key":"2818_CR19","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0046-8177(99)90115-6","volume":"30","author":"HJ Ree","year":"1999","unstructured":"Ree HJ, Kadin ME, Kikuchi M, Ko YH, Suzumiya J, Go JH (1999) Bcl-6 expression in reactive follicular hyperplasia, follicular lymphoma, and angioimmunoblastic T-cell lymphoma with hyperplastic germinal centers: heterogeneity of intrafollicular T-cells and their altered distribution in the pathogenesis of angioimmunoblastic T-cell lymphoma. Human pathology 30(4):403\u2013411","journal-title":"Human pathology"},{"key":"2818_CR20","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.2147\/ott.s91025","volume":"8","author":"B Huang","year":"2015","unstructured":"Huang B, Chen L, Bao C, Sun C, Li J, Wang L, Zhang X (2015) The expression status and prognostic significance of programmed cell death 1 ligand 1 in gastrointestinal tract cancer: a systematic review and meta-analysis. OncoTargets and therapy 8:2617\u20132625. doi: 10.2147\/ott.s91025","journal-title":"OncoTargets and therapy"},{"issue":"6","key":"2818_CR21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0131403","volume":"10","author":"P Wu","year":"2015","unstructured":"Wu P, Wu D, Li L, Chai Y, Huang J (2015) PD-L1 and survival in solid tumors: a meta-analysis. PloS one 10(6), e0131403. doi: 10.1371\/journal.pone.0131403","journal-title":"PloS one"},{"issue":"5","key":"2818_CR22","doi-asserted-by":"publisher","first-page":"e234","DOI":"10.1016\/s1470-2045(15)70103-8","volume":"16","author":"EA Hawkes","year":"2015","unstructured":"Hawkes EA, Grigg A, Chong G (2015) Programmed cell death-1 inhibition in lymphoma. The Lancet Oncology 16(5):e234\u2013245. doi: 10.1016\/s1470-2045(15)70103-8","journal-title":"The Lancet Oncology"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-016-2818-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00277-016-2818-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-016-2818-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T20:12:20Z","timestamp":1498335140000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00277-016-2818-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,3]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["2818"],"URL":"https:\/\/doi.org\/10.1007\/s00277-016-2818-4","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,3]]}}}