{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:00Z","timestamp":1772160420644,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1007\/s00277-022-04871-2","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T11:03:57Z","timestamp":1653563037000},"page":"2097-2098","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Increased blood levels of venetoclax due to intake of crushed venetoclax tablets"],"prefix":"10.1007","volume":"101","author":[{"given":"Maiko","family":"Anzai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0587-0091","authenticated-orcid":false,"given":"Takeo","family":"Yasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshito","family":"Gando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikio","family":"Shirota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"4871_CR1","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1056\/NEJMoa2012971","volume":"383","author":"CD DiNardo","year":"2020","unstructured":"DiNardo CD, Jonas BA, Pullarkat V, Thirman MJ, Garcia JS, Wei AH, Konopleva M, D\u00f6hner H, Letai A, Fenaux P, Koller E, Havelange V, Leber B, Esteve J, Wang J, Pejsa V, H\u00e1jek R, Porkka K, Ill\u00e9s \u00c1, Lavie D, Lemoli RM, Yamamoto K, Yoon SS, Jang JH, Yeh SP, Turgut M, Hong WJ, Zhou Y, Potluri J, Pratz KW (2020) Azacitidine and venetoclax in previously untreated acute myeloid leukemia. N Engl J Med 383:617\u2013629. https:\/\/doi.org\/10.1056\/NEJMoa2012971","journal-title":"N Engl J Med"},{"key":"4871_CR2","doi-asserted-by":"publisher","unstructured":"Yasu T, Gando Y, Nomura Y, Kosugi N, Kobayashi M (2022) Determination of venetoclax concentration in plasma using high-performance liquid chromatography. J Chromatogr Sci bmac027. https:\/\/doi.org\/10.1093\/chromsci\/bmac027","DOI":"10.1093\/chromsci\/bmac027"},{"key":"4871_CR3","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1080\/16078454.2020.1843752","volume":"25","author":"Y Guo","year":"2020","unstructured":"Guo Y, Liu B, Deng L, Qiao Y, Jian J (2020) The efficacy and adverse events of venetoclax in combination with hypomethylating agents treatment for patients with acute myeloid leukemia and myelodysplastic syndrome: a systematic review and meta-analysis. Hematology 25:414\u2013423. https:\/\/doi.org\/10.1080\/16078454.2020.1843752","journal-title":"Hematology"},{"key":"4871_CR4","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1002\/jcph.741","volume":"56","author":"AH Salem","year":"2016","unstructured":"Salem AH, Agarwal SK, Dunbar M, Nuthalapati S, Chien D, Freise KJ, Wong SL (2016) Effect of low- and high-fat meals on the pharmacokinetics of venetoclax, a selective first-in-class BCL-2 inhibitor. J Clin Pharmacol 56:1355\u20131361. https:\/\/doi.org\/10.1002\/jcph.741","journal-title":"J Clin Pharmacol"},{"key":"4871_CR5","unstructured":"AbbVie Inc. (2021) VENCLEXTA\u00ae prescribing information. https:\/\/www.rxabbvie.com\/pdf\/venclexta.pdf. Accessed 2022 Apr 5"},{"key":"4871_CR6","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.curtheres.2015.08.002","volume":"77","author":"J Fields","year":"2015","unstructured":"Fields J, Go JT, Schulze KS (2015) Pill properties that cause dysphagia and treatment failure. Curr Ther Res Clin Exp 77:79\u201382. https:\/\/doi.org\/10.1016\/j.curtheres.2015.08.002","journal-title":"Curr Ther Res Clin Exp"},{"key":"4871_CR7","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.ijpharm.2016.03.007","volume":"512","author":"F Liu","year":"2016","unstructured":"Liu F, Ghaffur A, Bains J, Hamdy S (2016) Acceptability of oral solid medicines in older adults with and without dysphagia: a nested pilot validation questionnaire based observational study. Int J Pharm 512:374\u2013381. https:\/\/doi.org\/10.1016\/j.ijpharm.2016.03.007","journal-title":"Int J Pharm"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-022-04871-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-022-04871-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-022-04871-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T05:22:40Z","timestamp":1660368160000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-022-04871-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,26]]},"references-count":7,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["4871"],"URL":"https:\/\/doi.org\/10.1007\/s00277-022-04871-2","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,26]]},"assertion":[{"value":"20 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from the patient for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}