{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T14:43:15Z","timestamp":1769265795715,"version":"3.49.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"CAMS innovation fund for medical sciences","award":["CIFMS 2021-I2M-1-003"],"award-info":[{"award-number":["CIFMS 2021-I2M-1-003"]}]},{"name":"Peking Union Medical Colleague Hospital Youth Research Foundation","award":["pumch201912367"],"award-info":[{"award-number":["pumch201912367"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970106"],"award-info":[{"award-number":["81970106"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1007\/s00277-022-04967-9","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T11:08:56Z","timestamp":1662462536000},"page":"2421-2431","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy and steroid-sparing effect of tacrolimus in patients with autoimmune cytopenia"],"prefix":"10.1007","volume":"101","author":[{"given":"Ruoxi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,9,6]]},"reference":[{"issue":"11","key":"4967_CR1","doi-asserted-by":"publisher","first-page":"2386","DOI":"10.1182\/blood-2008-07-162503","volume":"113","author":"F Rodeghiero","year":"2009","unstructured":"Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, Bussel JB, Cines DB, Chong BH, Cooper N, Godeau B, Lechner K, Mazzucconi MG, McMillan R, Sanz MA, Imbach P, Blanchette V, K\u00fchne T, Ruggeri M, George JN (2009) Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 113(11):2386\u20132393","journal-title":"Blood"},{"key":"4967_CR2","doi-asserted-by":"publisher","first-page":"100648","DOI":"10.1016\/j.blre.2019.100648","volume":"41","author":"U Jager","year":"2020","unstructured":"Jager U, Barcellini W, Broome CM, Gertz MA, Hill A, Hill QA, Jilma B, Kuter DJ, Michel M, Montillo M, Roth A, Zeerleder SS, Berentsen S (2020) Diagnosis and treatment of autoimmune hemolytic anemia in adults: recommendations from the First International Consensus Meeting. Blood Rev 41:100648","journal-title":"Blood Rev"},{"key":"4967_CR3","doi-asserted-by":"crossref","unstructured":"Norton A, Roberts I (2006) Management of Evans syndrome. Br J Haematol 132(2):125\u2013137","DOI":"10.1111\/j.1365-2141.2005.05809.x"},{"issue":"3","key":"4967_CR4","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1007\/s12185-019-02808-6","volume":"111","author":"K Takase","year":"2020","unstructured":"Takase K, Nagai H, Kadono M, Yoshioka T, Yoshio N, Hirabayashi Y, Ito T, Sawamura M, Yokoyama A, Yoshida S, Tsutsumi I, Otsuka M, Suehiro Y, Hidaka M, Yoshida I, Yokoyama H, Inoue H, Iida H, Nakayama M, Hishita T, Iwasaki H, Kada A, Saito AM, Kuroda Y (2020) High-dose dexamethasone therapy as the initial treatment for idiopathic thrombocytopenic purpura. Int J Hematol 111(3):388\u2013395","journal-title":"Int J Hematol"},{"issue":"1","key":"4967_CR5","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1080\/09537104.2019.1572875","volume":"31","author":"L Wang","year":"2020","unstructured":"Wang L, Xu L, Hao H, Jansen AJG, Liu G, Li H, Liu X, Zhao Y, Peng J, Hou M (2020) First line treatment of adult patients with primary immune thrombocytopenia: a real-world study. Platelets 31(1):55\u201361","journal-title":"Platelets"},{"issue":"8","key":"4967_CR6","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1007\/s00277-002-0488-x","volume":"81","author":"GE Pamuk","year":"2002","unstructured":"Pamuk GE, Pamuk ON, Ba\u015flar Z, Ong\u00f6ren S, Soysal T, Ferhano\u011flu B, Aydin Y, Ulk\u00fc B, Aktu\u011flu G, Akman N (2002) Overview of 321 patients with idiopathic thrombocytopenic purpura Retrospective analysis of the clinical features and response to therapy. Ann Hematol 81(8):436\u201340","journal-title":"Ann Hematol"},{"issue":"3","key":"4967_CR7","doi-asserted-by":"publisher","first-page":"E40","DOI":"10.1002\/ajh.23900","volume":"90","author":"TJ Gonz\u00e1lez-L\u00f3pez","year":"2015","unstructured":"Gonz\u00e1lez-L\u00f3pez TJ, Pascual C, \u00c1lvarez-Rom\u00e1n MT, Fern\u00e1ndez-Fuertes F, S\u00e1nchez-Gonz\u00e1lez B, Caparr\u00f3s I, Jarque I, Mingot-Castellano ME, Hern\u00e1ndez-Rivas JA, Mart\u00edn-Salces M, Sol\u00e1n L, Beneit P, Jim\u00e9nez R, Bernat S, Andrade MM, Cort\u00e9s M, Cortti MJ, P\u00e9rez-Crespo S, G\u00f3mez-N\u00fa\u00f1ez M, Olivera PE, P\u00e9rez-Rus G, Mart\u00ednez-Robles V, Alonso R, Fern\u00e1ndez-Rodr\u00edguez A, Arratibel MC, Perera M, Fern\u00e1ndez-Mi\u00f1ano C, Fuertes-Palacio MA, V\u00e1zquez-Paganini JA, Gutierrez-Jomarr\u00f3n I, Valcarce I, de Cabo E, Sainz A, Fisac R, Aguilar C, Paz Mart\u00ednez-Badas M, Pe\u00f1arrubia MJ, Calbacho M, de Cos C, Gonz\u00e1lez-Silva M, Coria E, Alonso A, Casaus A, Lua\u00f1a A, Gal\u00e1n P, Fern\u00e1ndez-Canal C, Garcia-Frade J, Gonz\u00e1lez-Porras JR (2015) Successful discontinuation of eltrombopag after complete remission in patients with primary immune thrombocytopenia. Am J Hematol 90(3):E40\u2013E43","journal-title":"Am J Hematol"},{"issue":"2","key":"4967_CR8","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1111\/bjh.13827","volume":"172","author":"A Newland","year":"2016","unstructured":"Newland A, Godeau B, Priego V, Viallard JF, L\u00f3pez Fern\u00e1ndez MF, Orejudos A, Eisen M (2016) Remission and platelet responses with romiplostim in primary immune thrombocytopenia: final results from a phase 2 study. Br J Haematol 172(2):262\u2013273","journal-title":"Br J Haematol"},{"issue":"3","key":"4967_CR9","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1111\/bjh.16672","volume":"191","author":"E Tj\u00f8nnfjord","year":"2020","unstructured":"Tj\u00f8nnfjord E, Holme PA, Darne B, Khelif A, Waage A, Michel M, Ben Romdhan N, Ghanima W (2020) Long-term outcomes of patients treated with rituximab as second-line treatment for adult immune thrombocytopenia - follow-up of the RITP study. Br J Haematol 191(3):460\u2013465","journal-title":"Br J Haematol"},{"issue":"6","key":"4967_CR10","doi-asserted-by":"publisher","first-page":"875","DOI":"10.3324\/haematol.2012.075648","volume":"98","author":"N Vianelli","year":"2013","unstructured":"Vianelli N, Palandri F, Polverelli N, Stasi R, Joelsson J, Johansson E, Ruggeri M, Zaja F, Cantoni S, Catucci AE, Candoni A, Morra E, Bj\u00f6rkholm M, Baccarani M, Rodeghiero F (2013) Splenectomy as a curative treatment for immune thrombocytopenia: a retrospective analysis of 233 patients with a minimum follow up of 10 years. Haematologica 98(6):875\u2013880","journal-title":"Haematologica"},{"issue":"2","key":"4967_CR11","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/bjh.15090","volume":"181","author":"F Rodeghiero","year":"2018","unstructured":"Rodeghiero F (2018) A critical appraisal of the evidence for the role of splenectomy in adults and children with ITP. Br J Haematol 181(2):183\u2013195","journal-title":"Br J Haematol"},{"issue":"23","key":"4967_CR12","doi-asserted-by":"publisher","first-page":"3829","DOI":"10.1182\/bloodadvances.2019000966","volume":"3","author":"C Neunert","year":"2019","unstructured":"Neunert C, Terrell DR, Arnold DM, Buchanan G, Cines DB, Cooper N, Cuker A, Despotovic JM, George JN, Grace RF, K\u00fchne T, Kuter DJ, Lim W, McCrae KR, Pruitt B, Shimanek H, Vesely SK (2019) American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv 3(23):3829\u20133866","journal-title":"Blood Adv"},{"issue":"22","key":"4967_CR13","doi-asserted-by":"publisher","first-page":"3780","DOI":"10.1182\/bloodadvances.2019000812","volume":"3","author":"D Provan","year":"2019","unstructured":"Provan D, Arnold DM, Bussel JB, Chong BH, Cooper N, Gernsheimer T, Ghanima W, Godeau B, Gonz\u00e1lez-L\u00f3pez TJ, Grainger J, Hou M, Kruse C, McDonald V, Michel M, Newland AC, Pavord S, Rodeghiero F, Scully M, Tomiyama Y, Wong RS, Zaja F, Kuter DJ (2019) Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv 3(22):3780\u20133817","journal-title":"Blood Adv"},{"issue":"4","key":"4967_CR14","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.autrev.2014.11.014","volume":"14","author":"Q Reynaud","year":"2015","unstructured":"Reynaud Q, Durieu I, Dutertre M, Ledochowski S, Durupt S, Michallet AS, Vital-Durand D, Lega JC (2015) Efficacy and safety of rituximab in auto-immune hemolytic anemia: a meta-analysis of 21 studies. Autoimmun Rev 14(4):304\u2013313","journal-title":"Autoimmun Rev"},{"key":"4967_CR15","doi-asserted-by":"publisher","first-page":"100648","DOI":"10.1016\/j.blre.2019.100648","volume":"41","author":"U J\u00e4ger","year":"2020","unstructured":"J\u00e4ger U, Barcellini W, Broome CM, Gertz MA, Hill A, Hill QA, Jilma B, Kuter DJ, Michel M, Montillo M, R\u00f6th A, Zeerleder SS, Berentsen S (2020) Diagnosis and treatment of autoimmune hemolytic anemia in adults: recommendations from the First International Consensus Meeting. Blood Rev 41:100648","journal-title":"Blood Rev"},{"key":"4967_CR16","doi-asserted-by":"crossref","unstructured":"Audia S, Grienay N, Mounier M, Michel M, Bonnotte\u00a0B  (2020) Evans\u2019 syndrome: from diagnosis to treatment. J Clin Med 9(12):3851","DOI":"10.3390\/jcm9123851"},{"key":"4967_CR17","doi-asserted-by":"publisher","first-page":"686480","DOI":"10.1155\/2010\/686480","volume":"2010","author":"KH Yoon","year":"2010","unstructured":"Yoon KH (2010) Efficacy and cytokine modulating effects of tacrolimus in systemic lupus erythematosus: a review. J Biomed Biotechnol 2010:686480","journal-title":"J Biomed Biotechnol"},{"issue":"10","key":"4967_CR18","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1097\/FPC.0b013e328364db84","volume":"23","author":"JM Barbarino","year":"2013","unstructured":"Barbarino JM, Staatz CE, Venkataramanan R, Klein TE, Altman RB (2013) PharmGKB summary: cyclosporine and tacrolimus pathways. Pharmacogenet Genomics 23(10):563\u2013585","journal-title":"Pharmacogenet Genomics"},{"issue":"12","key":"4967_CR19","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1016\/j.bbmt.2009.08.012","volume":"15","author":"H Yagasaki","year":"2009","unstructured":"Yagasaki H, Kojima S, Yabe H, Kato K, Kigasawa H, Sakamaki H, Tsuchida M, Kato S, Kawase T, Muramatsu H, Morishima Y, Kodera Y (2009) Tacrolimus\/methotrexate versus cyclosporine\/methotrexate as graft-versus-host disease prophylaxis in patients with severe aplastic anemia who received bone marrow transplantation from unrelated donors: results of matched pair analysis. Biol Blood Marrow Transplant 15(12):1603\u20131608","journal-title":"Biol Blood Marrow Transplant"},{"key":"4967_CR20","doi-asserted-by":"publisher","first-page":"5711","DOI":"10.2147\/DDDT.S275975","volume":"14","author":"Y Du","year":"2020","unstructured":"Du Y, Huang Y, Zhou W, Liu X, Chen F, Yang C, Chen M, Ruan J, Han B (2020) Effective tacrolimus treatment for patients with non-severe aplastic anemia that is refractory\/intolerant to cyclosporine A: a retrospective study. Drug Des Devel Ther 14:5711\u20135719","journal-title":"Drug Des Devel Ther"},{"key":"4967_CR21","doi-asserted-by":"crossref","unstructured":"Zufferey A, Kapur R, Semple\u00a0JW (2017) Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP). J Clin Med 6(2):16","DOI":"10.3390\/jcm6020016"},{"issue":"22","key":"4967_CR22","doi-asserted-by":"publisher","first-page":"4639","DOI":"10.1182\/blood-2010-04-281717","volume":"116","author":"W Bao","year":"2010","unstructured":"Bao W, Bussel JB, Heck S, He W, Karpoff M, Boulad N, Yazdanbakhsh K (2010) Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents. Blood 116(22):4639\u20134645","journal-title":"Blood"},{"issue":"9","key":"4967_CR23","doi-asserted-by":"publisher","first-page":"3746","DOI":"10.1182\/blood-2004-12-4692","volume":"105","author":"A Mqadmi","year":"2005","unstructured":"Mqadmi A, Zheng X, Yazdanbakhsh K (2005) CD4+CD25+ regulatory T cells control induction of autoimmune hemolytic anemia. Blood 105(9):3746\u20133748","journal-title":"Blood"},{"issue":"11","key":"4967_CR24","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1007\/s00277-016-2703-1","volume":"95","author":"E Khodadi","year":"2016","unstructured":"Khodadi E, Asnafi AA, Shahrabi S, Shahjahani M, Saki N (2016) Bone marrow niche in immune thrombocytopenia: a focus on megakaryopoiesis. Ann Hematol 95(11):1765\u20131776","journal-title":"Ann Hematol"},{"issue":"9","key":"4967_CR25","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1111\/jth.14214","volume":"16","author":"DF Zeng","year":"2018","unstructured":"Zeng DF, Chen F, Wang S, Chen SL, Xu Y, Shen MQ, Du CH, Wang C, Kong PY, Cheng TM, Su YP, Wang JP (2018) Autoantibody against integrin \u03b1(v) \u03b2(3) contributes to thrombocytopenia by blocking the migration and adhesion of megakaryocytes. J Thromb Haemost 16(9):1843\u20131856","journal-title":"J Thromb Haemost"},{"issue":"10","key":"4967_CR26","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.1007\/s00277-020-04203-2","volume":"99","author":"X Wang","year":"2020","unstructured":"Wang X, Lu J, Wei G, Tong H, Zhou J, Ding Y, Zhang S, Xu X, Lai R, Luo Q, Ju W, Yan Z, Zeng L, Xu K, Qiao J (2020) Tacrolimus ameliorates thrombocytopenia in an ITP mouse model. Ann Hematol 99(10):2315\u20132322","journal-title":"Ann Hematol"},{"issue":"6","key":"4967_CR27","doi-asserted-by":"publisher","first-page":"2233","DOI":"10.1016\/S0041-1345(03)00774-7","volume":"35","author":"A Debska-Slizie\u0144","year":"2003","unstructured":"Debska-Slizie\u0144 A, Chamienia A, Kr\u00f3l E, Zdrojewski Z, Pirski I, Zadrozny D, Sledzi\u0144ski Z, Rutkowski B (2003) Hemolytic anemia after renal transplantation: analysis of case reports. Transplant Proc 35(6):2233\u20132237","journal-title":"Transplant Proc"},{"issue":"26","key":"4967_CR28","doi-asserted-by":"publisher","first-page":"e241","DOI":"10.1200\/JCO.2011.40.0499","volume":"30","author":"U Gergis","year":"2012","unstructured":"Gergis U, Ibrahim M, Al-Kazaz M, Parkash S, Gergis E, Desancho M (2012) Successful treatment with tacrolimus of a patient with severe idiopathic thrombocytopenic purpura after allogeneic bone marrow transplantation. J Clin Oncol 30(26):e241\u2013e242","journal-title":"J Clin Oncol"},{"issue":"1","key":"4967_CR29","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1007\/s10637-014-0155-9","volume":"33","author":"S Tabchi","year":"2015","unstructured":"Tabchi S, Hanna C, Kourie HR, Aftimos P, El Osta L, Ghosn M (2015) Successful treatment of Evans syndrome with tacrolimus. Invest New Drugs 33(1):254\u2013256","journal-title":"Invest New Drugs"},{"issue":"5 Suppl","key":"4967_CR30","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1002\/pbc.20974","volume":"47","author":"CM Bennett","year":"2006","unstructured":"Bennett CM, de Jong JL, Neufeld EJ (2006) Targeted ITP strategies: do they elucidate the biology of ITP and related disorders? Pediatr Blood Cancer 47(5 Suppl):706\u2013709","journal-title":"Pediatr Blood Cancer"},{"issue":"1","key":"4967_CR31","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1080\/16078454.2020.1852763","volume":"25","author":"Y Du","year":"2020","unstructured":"Du Y, Yang C, Chen M, Ruan J, Huang Y, Chen F, Han B (2020) Tacrolimus is effective in relapsed\/refractory autoimmune cytopenias: results of a single-center retrospective study. Hematol 25(1):478\u2013483","journal-title":"Hematol"},{"issue":"6","key":"4967_CR32","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1007\/s00296-010-1366-9","volume":"31","author":"K Suzuki","year":"2011","unstructured":"Suzuki K, Kameda H, Amano K, Nagasawa H, Takei H, Nishi E, Okuyama A, Tsuzaka K, Takeuchi T (2011) Single center prospective study of tacrolimus efficacy and safety in the treatment of various manifestations in systemic lupus erythematosus. Rheumatol Int 31(6):757\u2013763","journal-title":"Rheumatol Int"},{"issue":"10","key":"4967_CR33","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1177\/0961203311406766","volume":"20","author":"H Li","year":"2011","unstructured":"Li H, Zhang X, Chen J (2011) Successful treatment of steroid-refractory systemic lupus erythematosus-associated protein-losing enteropathy using combination therapy with tacrolimus and steroid. Lupus 20(10):1109\u20131111","journal-title":"Lupus"},{"issue":"1","key":"4967_CR34","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1681\/ASN.2019050546","volume":"32","author":"HJ Chin","year":"2021","unstructured":"Chin HJ, Chae DW, Kim YC, An WS, Ihm C, Jin DC, Kim SG, Kim YL, Kim YS, Kim YG, Koo HS, Lee JE, Lee KW, Oh J, Park JH, Jiang H, Lee H, Lee SK (2021) Comparison of the efficacy and safety of tacrolimus and low-dose corticosteroid with high-dose corticosteroid for minimal change nephrotic syndrome in adults. J Am Soc Nephrol 32(1):199\u2013210","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"4967_CR35","doi-asserted-by":"publisher","first-page":"393","DOI":"10.5414\/CNP65393","volume":"65","author":"TH Westhoff","year":"2006","unstructured":"Westhoff TH, Schmidt S, Zidek W, Beige J, van der Giet M (2006) Tacrolimus in steroid-resistant and steroid-dependent nephrotic syndrome. Clin Nephrol 65(6):393\u2013400","journal-title":"Clin Nephrol"},{"issue":"9","key":"4967_CR36","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1136\/jnnp-2011-300148","volume":"82","author":"H Yoshikawa","year":"2011","unstructured":"Yoshikawa H, Kiuchi T, Saida T, Takamori M (2011) Randomised, double-blind, placebo-controlled study of tacrolimus in myasthenia gravis. J Neurol Neurosurg Psychiatry 82(9):970\u2013977","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"11","key":"4967_CR37","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1111\/j.1600-6143.2004.00583.x","volume":"4","author":"R Borrows","year":"2004","unstructured":"Borrows R, Loucaidou M, Van Tromp J, Cairns T, Griffith M, Hakim N, McLean A, Palmer A, Papalois V, Taube D (2004) Steroid sparing with tacrolimus and mycophenolate mofetil in renal transplantation. Am J Transplant 4(11):1845\u20131851","journal-title":"Am J Transplant"},{"issue":"2","key":"4967_CR38","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1002\/ajh.20992","volume":"83","author":"R McMillan","year":"2008","unstructured":"McMillan R, Bussel JB, George JN, Lalla D, Nichol JL (2008) Self-reported health-related quality of life in adults with chronic immune thrombocytopenic purpura. Am J Hematol 83(2):150\u2013154","journal-title":"Am J Hematol"},{"issue":"2","key":"4967_CR39","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/j.1365-2257.2004.00591.x","volume":"26","author":"J Zimmer","year":"2004","unstructured":"Zimmer J, Andr\u00e8s E, Noel E, Koumarianou A, Blickl\u00e9 JF, Maloisel F (2004) Current management of adult idiopathic thrombocytopenic purpura in practice: a cohort study of 201 patients from a single center. Clin Lab Haematol 26(2):137\u2013142","journal-title":"Clin Lab Haematol"},{"issue":"5","key":"4967_CR40","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/S0002-9343(99)80342-8","volume":"98","author":"R Stasi","year":"1995","unstructured":"Stasi R, Stipa E, Masi M, Cecconi M, Scim\u00f2 MT, Oliva F, Sciarra A, Perrotti AP, Adomo G, Amadori S et al (1995) Long-term observation of 208 adults with chronic idiopathic thrombocytopenic purpura. Am J Med 98(5):436\u2013442","journal-title":"Am J Med"},{"issue":"3","key":"4967_CR41","doi-asserted-by":"publisher","first-page":"139","DOI":"10.5694\/j.1326-5377.1986.tb112242.x","volume":"144","author":"JPMRC Seale","year":"1986","unstructured":"Seale JPMRC (1986) Side-effects of corticosteroid agents. Med J Aust 144(3):139\u2013142","journal-title":"Med J Aust"},{"issue":"12","key":"4967_CR42","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1080\/17474086.2018.1548930","volume":"11","author":"HG Sest\u00f8l","year":"2018","unstructured":"Sest\u00f8l HG, Trangb\u00e6k SM, Bussel JB, Frederiksen H (2018) Health-related quality of life in adult primary immune thrombocytopenia. Expert Rev Hematol 11(12):975\u2013985","journal-title":"Expert Rev Hematol"},{"key":"4967_CR43","doi-asserted-by":"crossref","unstructured":"Terrell DR, Neunert CE, Cooper N, Heitink-Poll\u00e9 KM, Kruse C, Imbach P, K\u00fchne T, Ghanima\u00a0W (2020) Immune thrombocytopenia (ITP): current limitations in patient management. Medicina (Kaunas) 56(12):667","DOI":"10.3390\/medicina56120667"},{"key":"4967_CR44","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.intimp.2019.03.002","volume":"70","author":"D Liu","year":"2019","unstructured":"Liu D, Yang Y, Kuang F, Qing S, Hu B, Yu X (2019) Risk of infection with different immunosuppressive drugs combined with glucocorticoids for the treatment of idiopathic membranous nephropathy: a pairwise and network meta-analysis. Int Immunopharmacol 70:354\u2013361","journal-title":"Int Immunopharmacol"},{"issue":"16","key":"4967_CR45","doi-asserted-by":"publisher","first-page":"4190","DOI":"10.1182\/blood-2010-08-302984","volume":"117","author":"C Neunert","year":"2011","unstructured":"Neunert C, Lim W, Crowther M, Cohen A, Solberg L Jr, Crowther MA (2011) The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 117(16):4190\u20134207","journal-title":"Blood"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-022-04967-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-022-04967-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-022-04967-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T06:19:54Z","timestamp":1665123594000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-022-04967-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,6]]},"references-count":45,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["4967"],"URL":"https:\/\/doi.org\/10.1007\/s00277-022-04967-9","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,6]]},"assertion":[{"value":"19 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the ethics committee of Peking Union Medical College Hospital and was conducted in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all patients for being included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}