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Latent profile analyses (LPA)\u00a0of MM patients were\u00a0used to\u00a0identify\u00a0profiles of patients with\u00a0similar\u00a0PAHCO and\u00a0symptom burden. Analysis of variance\u00a0was\u00a0applied\u00a0to\u00a0investigate group differences in\u00a0important covariates.\u00a0<jats:italic>N<\/jats:italic>\u2009=\u200998 MM patients (57% male, age 64\u2009\u00b1\u20099\u00a0years) could be assigned to three distinct PAHCO profiles: 46% were patients with high PAHCO, 48% patients with moderate, and 5% were patients with low PAHCO. The mean probability to be assigned to a certain profile was over 99%. The first group showed significant higher physical activity (PA) and lower comorbidities. Regarding symptom burden, three different profiles exist, including group one (32% of patients) with very low symptom burden, profile two (40%) with medium symptom burden, and group three (15%) with very high symptom burden (mean probability\u2009\u2265\u200998%). Patients in profile one had a lower number of treatment lines compared to the other profiles. Patients who were assigned to the high PAHCO profile were more likely to display a milder symptoms profile. In this exploratory analysis, we identified different patient profiles for PAHCO and symptom burden that may be used to individualize exercise recommendations and supervision modalities in MM patients. PAHCO and symptom burden level may be used to stratify MM patients in order to provide more personalized and effective exercise counseling. The profiles require individualized exercise recommendations and different supervision modalities, including educational instructions tailored particularly to every patient\u2019s needs, according to their PAHCO and symptom profile.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial registration number<\/jats:title>\n                <jats:p>NCT04328038.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00277-023-05326-y","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T22:01:31Z","timestamp":1687644091000},"page":"3091-3102","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Physical activity-related health competence and symptom burden for exercise prescription in patients with multiple myeloma: a latent profile analysis"],"prefix":"10.1007","volume":"102","author":[{"given":"Rea","family":"Kuehl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Koeppel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hartmut","family":"Goldschmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imad","family":"Maatouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Friederike","family":"Rosenberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5971-5436","authenticated-orcid":false,"given":"Joachim","family":"Wiskemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,6,24]]},"reference":[{"issue":"1","key":"5326_CR1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1002\/cphy.c180016","volume":"9","author":"JF Christensen","year":"2018","unstructured":"Christensen JF, Simonsen C, Hojman P (2018) Exercise training in cancer control and treatment. 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