{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:18:58Z","timestamp":1786979938371,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC82000180"],"award-info":[{"award-number":["NSFC82000180"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1007\/s00277-024-05753-5","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T22:01:32Z","timestamp":1713477692000},"page":"3199-3206","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Psychological and physical side effects during G-CSF mobilization in related donors of allo-HCT"],"prefix":"10.1007","volume":"103","author":[{"given":"Lingxia","family":"Cai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diange","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfei","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixia","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangquan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinna","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiyun","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyi","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yishan","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,19]]},"reference":[{"key":"5753_CR1","doi-asserted-by":"publisher","unstructured":"Siddiq S, Pamphilon D, Brunskill S et al 2009 bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors. Cochrane Database Syst Rev (1):CD006406https:\/\/doi.org\/10.1002\/14651858.CD006406.pub2","DOI":"10.1002\/14651858.CD006406.pub2"},{"issue":"4","key":"5753_CR2","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1054\/blre.2000.0138","volume":"14","author":"S Fu","year":"2000","unstructured":"Fu S, Liesveld J (2000) Mobilization of hematopoietic stem cells. Blood Rev 14(4):205\u2013218. https:\/\/doi.org\/10.1054\/blre.2000.0138","journal-title":"Blood Rev"},{"key":"5753_CR3","doi-asserted-by":"publisher","unstructured":"Luo Q, Li H, Shan W et al 2021 specific blood cells derived from pluripotent stem cells: an emerging field with great potential in clinical cell therapy. Stem Cells Int https:\/\/doi.org\/10.1155\/2021\/9919422","DOI":"10.1155\/2021\/9919422"},{"issue":"4","key":"5753_CR4","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1007\/s12185-013-1298-8","volume":"97","author":"SH Chen","year":"2013","unstructured":"Chen SH, Wang TF, Yang KL (2013) Hematopoietic stem cell donation. Int J Hematol 97(4):446\u2013455. https:\/\/doi.org\/10.1007\/s12185-013-1298-8","journal-title":"Int J Hematol"},{"issue":"2","key":"5753_CR5","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.tracli.2018.02.004","volume":"25","author":"V Moalic-Allain","year":"2018","unstructured":"Moalic-Allain V (2018) Medical and ethical considerations on hematopoietic stem cells mobilization for healthy donors. Transfus Clin Biol 25(2):136\u2013143. https:\/\/doi.org\/10.1016\/j.tracli.2018.02.004","journal-title":"Transfus Clin Biol"},{"issue":"2","key":"5753_CR6","doi-asserted-by":"publisher","first-page":"189","DOI":"10.2174\/157488806776956869","volume":"1","author":"R Moog","year":"2006","unstructured":"Moog R (2006) Mobilization and harvesting of peripheral blood stem cells. Curr Stem Cell Res Ther 1(2):189\u2013201. https:\/\/doi.org\/10.2174\/157488806776956869","journal-title":"Curr Stem Cell Res Ther"},{"issue":"1","key":"5753_CR7","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1182\/blood-2012-03-417667","volume":"121","author":"MA Pulsipher","year":"2013","unstructured":"Pulsipher MA, Chitphakdithai P, Logan BR et al (2013) Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program. Blood 121(1):197\u2013206. https:\/\/doi.org\/10.1182\/blood-2012-03-417667","journal-title":"Blood"},{"key":"5753_CR8","doi-asserted-by":"publisher","unstructured":"Pulsipher MA, Chitphakdithai P, Miller JP et al 2009 Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program. Blood.113(15):3604-11https:\/\/doi.org\/10.1182\/blood-2008-08-175323","DOI":"10.1182\/blood-2008-08-175323"},{"key":"5753_CR9","doi-asserted-by":"publisher","unstructured":"Xu LP, Wu DP, Han MZ et al 2017 a review of hematopoietic cell transplantation in China: data and trends during 2008\u20132016. Bone Marrow Transpl. 52(11):1512\u20131518https:\/\/doi.org\/10.1038\/bmt.2017.59","DOI":"10.1038\/bmt.2017.59"},{"issue":"12","key":"5753_CR10","doi-asserted-by":"publisher","first-page":"2365","DOI":"10.1016\/j.bbmt.2020.08.016","volume":"26","author":"GE Switzer","year":"2020","unstructured":"Switzer GE, Bruce JG, Kiefer DM et al (2020) Health-Related Quality-of-life comparison of adult related and unrelated HSC donors: an RDSafe Study. Biol Blood Marrow Transpl 26(12):2365\u20132371. https:\/\/doi.org\/10.1016\/j.bbmt.2020.08.016","journal-title":"Biol Blood Marrow Transpl"},{"key":"5753_CR11","doi-asserted-by":"publisher","unstructured":"Farhadfar N, Ahn KW, Bo-Subait S et al 2022 The Impact of Pre-Apheresis Health Related Quality of Life on Peripheral Blood Progenitor Cell Yield and Donor\u2019s Health and Outcome: Secondary Analysis of Patient-Reported Outcome Data from the RDSafe and BMT CTN 0201 Clinical Trials. Transpl Cell Ther. 28(9):603e1- https:\/\/doi.org\/10.1016\/j.jtct.2022.05.042","DOI":"10.1016\/j.jtct.2022.05.042"},{"key":"5753_CR12","doi-asserted-by":"publisher","unstructured":"Giralt S, Costa L, Schriber J et al 2014 optimizing autologous stem cell mobilization strategies to improve patient outcomes: consensus guidelines and recommendations. Biol Blood Marrow Transpl. 20(3):295\u2013308https:\/\/doi.org\/10.1016\/j.bbmt.2013.10.013","DOI":"10.1016\/j.bbmt.2013.10.013"},{"issue":"1","key":"5753_CR13","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.psc.2011.11.001","volume":"35","author":"S Rackley","year":"2012","unstructured":"Rackley S, Bostwick JM (2012) Depression in medically ill patients. Psychiatr Clin North Am 35(1):231\u2013247. https:\/\/doi.org\/10.1016\/j.psc.2011.11.001","journal-title":"Psychiatr Clin North Am"},{"key":"5753_CR14","doi-asserted-by":"publisher","unstructured":"Tiller JW (2013) Depression and anxiety. Med J Aust 199(S6). https:\/\/doi.org\/10.5694\/mja12.10628","DOI":"10.5694\/mja12.10628"},{"key":"5753_CR15","doi-asserted-by":"publisher","unstructured":"Chen H, Feng H, Liu Y et al 2023 anxiety, depression, insomnia, and PTSD among college students after optimizing the COVID-19 response in China. J Affect Disord. 337:https:\/\/doi.org\/10.1016\/j.jad.2023.05.076","DOI":"10.1016\/j.jad.2023.05.076"},{"issue":"1 Suppl 2","key":"5753_CR16","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/s0037-1963(00)90087-8","volume":"37","author":"JF DiPersio","year":"2000","unstructured":"DiPersio JF, Khoury H, Haug J et al (2000) Innovations in allogeneic stem-cell transplantation. Semin Hematol 37(1 Suppl 2):33\u201341. https:\/\/doi.org\/10.1016\/s0037-1963(00)90087-8","journal-title":"Semin Hematol"},{"key":"5753_CR17","doi-asserted-by":"publisher","unstructured":"Watt SM, Hua P, Roberts I (2022) Increasing complexity of Molecular landscapes in Human hematopoietic stem and progenitor cells during development and aging. Int J Mol Sci 23. https:\/\/doi.org\/10.3390\/ijms23073675","DOI":"10.3390\/ijms23073675"},{"issue":"2","key":"5753_CR18","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.blre.2013.12.003","volume":"28","author":"WG Murphy","year":"2014","unstructured":"Murphy WG (2014) The sex difference in haemoglobin levels in adults - mechanisms, causes, and consequences. Blood Rev 28(2):41\u201347. https:\/\/doi.org\/10.1016\/j.blre.2013.12.003","journal-title":"Blood Rev"},{"key":"5753_CR19","doi-asserted-by":"crossref","unstructured":"Li Y, Chang Y, Xu L et al 2014 negative association of donor age with CD34(+) cell dose in mixture allografts of G-CSF-primed bone marrow and G-CSF-mobilized peripheral blood harvests. Chin Med J (Engl). 127(20):3597\u20133601","DOI":"10.3760\/cma.j.issn.0366-6999.20141161"},{"key":"5753_CR20","doi-asserted-by":"publisher","unstructured":"Zeng X, Li X, Li X et al 2023 fecal microbiota transplantation from young mice rejuvenates aged hematopoietic stem cells by suppressing inflammation. Blood. doi.https:\/\/doi.org\/10.1182\/blood.2022017514","DOI":"10.1182\/blood.2022017514"},{"key":"5753_CR21","doi-asserted-by":"publisher","unstructured":"Kollman C, Howe CW, Anasetti C et al 2001 Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood. 98(7):2043\u20132051https:\/\/doi.org\/10.1182\/blood.v98.7.2043","DOI":"10.1182\/blood.v98.7.2043"},{"issue":"1","key":"5753_CR22","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.bbmt.2013.10.024","volume":"20","author":"GE Switzer","year":"2014","unstructured":"Switzer GE, Bruce JG, Harrington D et al (2014) Health-related quality of life of bone marrow versus peripheral blood stem cell donors: a prespecified subgroup analysis from a phase III RCT-BMTCTN protocol 0201. Biol Blood Marrow Transpl 20(1):118\u2013127. https:\/\/doi.org\/10.1016\/j.bbmt.2013.10.024","journal-title":"Biol Blood Marrow Transpl"},{"issue":"3","key":"5753_CR23","first-page":"237","volume":"63","author":"I Bojanic","year":"2009","unstructured":"Bojanic I, Cepulic BG, Mazic S (2009) Collection of hematopoietic progenitor cells from healthy donors]. Acta Med Croatica 63(3):237\u2013244","journal-title":"Acta Med Croatica"},{"issue":"1","key":"5753_CR24","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1093\/bja\/aet127","volume":"111","author":"EJ Bartley","year":"2013","unstructured":"Bartley EJ, Fillingim RB (2013) Sex differences in pain: a brief review of clinical and experimental findings. Br J Anaesth 111(1):52\u201358. https:\/\/doi.org\/10.1093\/bja\/aet127","journal-title":"Br J Anaesth"},{"issue":"5","key":"5753_CR25","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1007\/s00127-014-0847-7","volume":"49","author":"AM Doherty","year":"2014","unstructured":"Doherty AM, Gaughran F (2014) The interface of physical and mental health. Soc Psychiatry Psychiatr Epidemiol 49(5):673\u2013682. https:\/\/doi.org\/10.1007\/s00127-014-0847-7","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"5753_CR26","doi-asserted-by":"publisher","unstructured":"Hagerty SL, Ellingson JM, Helmuth TB et al 2019 an overview and proposed Research Framework for studying Co-occurring Mental- and physical-health dysfunction. Perspect Psychol Sci. 14(4):633\u2013645https:\/\/doi.org\/10.1177\/1745691619827010","DOI":"10.1177\/1745691619827010"},{"key":"5753_CR27","doi-asserted-by":"publisher","unstructured":"Ni X, Su H, Lv Y et al 2022 the major risk factor for depression in the Chinese middle-aged and elderly population: a cross-sectional study. Front Psychiatry https:\/\/doi.org\/10.3389\/fpsyt.2022.986389","DOI":"10.3389\/fpsyt.2022.986389"},{"key":"5753_CR28","doi-asserted-by":"publisher","unstructured":"Pulsipher MA, Logan BR, Kiefer DM et al 2019 higher risks of toxicity and incomplete recovery in 13- to 17-Year-old females after Marrow Donation: RDSafe peds results. Biol Blood Marrow Transpl. 25(5):955\u2013964https:\/\/doi.org\/10.1016\/j.bbmt.2018.12.765","DOI":"10.1016\/j.bbmt.2018.12.765"},{"key":"5753_CR29","doi-asserted-by":"publisher","unstructured":"Aarons GA, Monn AR, Leslie LK et al 2008 Association between mental and physical health problems in high-risk adolescents: a longitudinal study. J Adolesc Health. 43(3):260\u2013267https:\/\/doi.org\/10.1016\/j.jadohealth.2008.01.013","DOI":"10.1016\/j.jadohealth.2008.01.013"},{"issue":"5","key":"5753_CR30","doi-asserted-by":"publisher","first-page":"735","DOI":"10.3324\/haematol.12285","volume":"93","author":"J de la Rubia","year":"2008","unstructured":"de la Rubia J, de Arriba F, Arbona C et al (2008) Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry. Haematologica 93(5):735\u2013740. https:\/\/doi.org\/10.3324\/haematol.12285","journal-title":"Haematologica"},{"issue":"4","key":"5753_CR31","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1038\/sj.bmt.1705066","volume":"36","author":"C Tassi","year":"2005","unstructured":"Tassi C, Tazzari PL, Bonifazi F et al (2005) Short- and long-term haematological surveillance of healthy donors of allogeneic peripheral haematopoietic progenitors mobilized with G-CSF: a single institution prospective study. Bone Marrow Transpl 36(4):289\u2013294. https:\/\/doi.org\/10.1038\/sj.bmt.1705066","journal-title":"Bone Marrow Transpl"},{"key":"5753_CR32","doi-asserted-by":"publisher","unstructured":"He K, Liu X, Hoffman RD et al 2022 G-CSF\/GM-CSF-induced hematopoietic dysregulation in the progression of solid tumors. FEBS Open Bio. 12(7):1268\u20131285https:\/\/doi.org\/10.1002\/2211-5463.13445","DOI":"10.1002\/2211-5463.13445"},{"issue":"2","key":"5753_CR33","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1038\/leu.2010.248","volume":"25","author":"AM Greenbaum","year":"2011","unstructured":"Greenbaum AM, Link DC (2011) Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization. Leukemia 25(2):211\u2013217. https:\/\/doi.org\/10.1038\/leu.2010.248","journal-title":"Leukemia"},{"issue":"1","key":"5753_CR34","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1080\/08977190500055836","volume":"23","author":"AW Roberts","year":"2005","unstructured":"Roberts AW (2005) G-CSF: a key regulator of neutrophil production, but that\u2019s not all! Growth Factors 23(1):33\u201341. https:\/\/doi.org\/10.1080\/08977190500055836","journal-title":"Growth Factors"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-024-05753-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-024-05753-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-024-05753-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T02:06:19Z","timestamp":1722045979000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-024-05753-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,19]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["5753"],"URL":"https:\/\/doi.org\/10.1007\/s00277-024-05753-5","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,19]]},"assertion":[{"value":"24 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by Ethic Committee of the First Affiliated Hospital, Zhejiang University School of Medicine (Approval NO: IIT20210094B).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all patients and consist with the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no conflict of interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}