{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:28:54Z","timestamp":1755221334689,"version":"3.43.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1007\/s00277-025-06508-6","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T02:34:04Z","timestamp":1752892444000},"page":"3763-3777","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Distinct structural and numerical chromosome abnormalities determine the MYC status in diffuse large B-Cell lymphoma and help differentiate from Burkitt lymphoma: a cytogenetic data analysis using unsupervised and AI-driven prediction models"],"prefix":"10.1007","volume":"104","author":[{"given":"Rolando","family":"Garc\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shankar","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehta","family":"Shashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick","family":"Coffman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasad","family":"Koduru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,19]]},"reference":[{"issue":"9","key":"6508_CR1","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1038\/bjc.2015.94","volume":"112","author":"A Smith","year":"2015","unstructured":"Smith A, Crouch S, Lax S, Li J, Painter D, Howell D et al (2015) Lymphoma incidence, survival and prevalence 2004\u20132014: sub-type analyses from the uk\u2019s haematological malignancy research network. Br J Cancer 112(9):1575\u20131584. https:\/\/doi.org\/10.1038\/bjc.2015.94","journal-title":"Br J Cancer"},{"issue":"25","key":"6508_CR2","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1056\/NEJMoa012914","volume":"346","author":"A Rosenwald","year":"2002","unstructured":"Rosenwald A, Wright G, Chan WC, Connors JM, Campo E, Fisher RI et al (2002) The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 346(25):1937\u20131947. https:\/\/doi.org\/10.1056\/NEJMoa012914","journal-title":"N Engl J Med"},{"issue":"5","key":"6508_CR3","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1002\/ajh.26151","volume":"96","author":"S Susanibar-Adaniya","year":"2021","unstructured":"Susanibar-Adaniya S, Barta SK (2021) 2021 update on diffuse large B cell lymphoma: A review of current data and potential applications on risk stratification and management. Am J Hematol 96(5):617\u2013629. https:\/\/doi.org\/10.1002\/ajh.26151","journal-title":"Am J Hematol"},{"issue":"5","key":"6508_CR4","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1053\/j.seminhematol.2023.11.006","volume":"60","author":"LK Hilton","year":"2023","unstructured":"Hilton LK, Scott DW, Morin RD (2023) Biological heterogeneity in diffuse large B-cell lymphoma. Semin Hematol 60(5):267\u2013276. https:\/\/doi.org\/10.1053\/j.seminhematol.2023.11.006","journal-title":"Semin Hematol"},{"issue":"21","key":"6508_CR5","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1182\/blood.2022015854","volume":"140","author":"L de Leval","year":"2022","unstructured":"de Leval L, Alizadeh AA, Bergsagel PL, Campo E, Davies A, Dogan A et al (2022) Genomic profiling for clinical decision making in lymphoid neoplasms. Blood 140(21):2193\u20132227. https:\/\/doi.org\/10.1182\/blood.2022015854","journal-title":"Blood"},{"issue":"6769","key":"6508_CR6","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1038\/35000501","volume":"403","author":"AA Alizadeh","year":"2000","unstructured":"Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A et al (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403(6769):503\u2013511. https:\/\/doi.org\/10.1038\/35000501","journal-title":"Nature"},{"issue":"1","key":"6508_CR7","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41392-023-01358-y","volume":"8","author":"R Shen","year":"2023","unstructured":"Shen R, Fu D, Dong L, Zhang MC, Shi Q et al (2023) Simplified algorithm for genetic subtyping in diffuse large B-cell lymphoma. Signal Transduct Target Ther 8(1):145. https:\/\/doi.org\/10.1038\/s41392-023-01358-y","journal-title":"Signal Transduct Target Ther"},{"issue":"1","key":"6508_CR8","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/bjh.12343","volume":"162","author":"AM Perry","year":"2013","unstructured":"Perry AM, Crockett D, Dave BJ, Althof P, Winkler L, Smith LM et al (2013) B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma: study of 39 cases. Br J Haematol 162(1):40\u201349. https:\/\/doi.org\/10.1111\/bjh.12343","journal-title":"Br J Haematol"},{"issue":"18","key":"6508_CR9","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1182\/blood-2017-12-820605","volume":"131","author":"DW Scott","year":"2018","unstructured":"Scott DW, King RL, Staiger AM, Ben-Neriah S, Jiang A, Horn H et al (2018) High-grade B-cell lymphoma with MYC and BCL2 and\/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology. Blood 131(18):2060\u20132064. https:\/\/doi.org\/10.1182\/blood-2017-12-820605","journal-title":"Blood"},{"issue":"8","key":"6508_CR10","doi-asserted-by":"publisher","first-page":"499","DOI":"10.46883\/2022.25920970","volume":"36","author":"PC Johnson","year":"2022","unstructured":"Johnson PC, Abramson JS (2022) Current treatment of Burkitt lymphoma and High-Grade B-Cell lymphomas. Oncol (Williston Park) 36(8):499\u2013505. https:\/\/doi.org\/10.46883\/2022.25920970","journal-title":"Oncol (Williston Park)"},{"issue":"17","key":"6508_CR11","doi-asserted-by":"publisher","first-page":"3533","DOI":"10.1182\/blood-2009-05-220095","volume":"114","author":"KJ Savage","year":"2009","unstructured":"Savage KJ, Johnson NA, Ben-Neriah S, Connors JM, Sehn LH, Farinha P et al (2009) MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy. Blood 114(17):3533\u20133537. https:\/\/doi.org\/10.1182\/blood-2009-05-220095","journal-title":"Blood"},{"issue":"20","key":"6508_CR12","doi-asserted-by":"publisher","first-page":"3360","DOI":"10.1200\/JCO.2009.26.3947","volume":"28","author":"S Barrans","year":"2010","unstructured":"Barrans S, Crouch S, Smith A, Turner K, Owen R, Patmore R et al (2010) Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab. J Clin Oncol 28(20):3360\u20133365. https:\/\/doi.org\/10.1200\/JCO.2009.26.3947","journal-title":"J Clin Oncol"},{"issue":"2","key":"6508_CR13","doi-asserted-by":"publisher","first-page":"255","DOI":"10.3324\/haematol.2012.066209","volume":"98","author":"C Visco","year":"2013","unstructured":"Visco C, Tzankov A, Xu-Monette ZY, Miranda RN, Tai YC et al (2013) Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an international DLBCL rituximab-CHOP consortium program study. Haematologica 98(2):255\u2013263. https:\/\/doi.org\/10.3324\/haematol.2012.066209","journal-title":"Haematologica"},{"issue":"2","key":"6508_CR14","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.cell.2017.09.027","volume":"171","author":"A Reddy","year":"2017","unstructured":"Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A et al (2017) Genetic and functional drivers of diffuse large B cell lymphoma. Cell 171(2):481\u2013494e415. https:\/\/doi.org\/10.1016\/j.cell.2017.09.027","journal-title":"Cell"},{"issue":"4","key":"6508_CR15","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/j.ccell.2020.03.015","volume":"37","author":"GW Wright","year":"2020","unstructured":"Wright GW, Huang DW, Phelan JD, Coulibaly ZA, Roulland S, Young RM, Wang JQ, Schmitz R, Morin RD, Tang J, Jiang A, Bagaev A, Plotnikova O, Kotlov N, Johnson CA, Wilson WH, Scott DW, Staudt LM (2020) A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications. Cancer Cell 37(4):551\u2013568e514. https:\/\/doi.org\/10.1016\/j.ccell.2020.03.015","journal-title":"Cancer Cell"},{"issue":"5","key":"6508_CR16","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1038\/s41591-018-0016-8","volume":"24","author":"B Chapuy","year":"2018","unstructured":"Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS et al (2018) Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nat Med 24(5):679\u2013690. https:\/\/doi.org\/10.1038\/s41591-018-0016-8","journal-title":"Nat Med"},{"issue":"9","key":"6508_CR17","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1056\/NEJMra2027612","volume":"384","author":"LH Sehn","year":"2021","unstructured":"Sehn LH, Salles G (2021) Diffuse large B-Cell lymphoma. N Engl J Med 384(9):842\u2013858. https:\/\/doi.org\/10.1056\/NEJMra2027612","journal-title":"N Engl J Med"},{"issue":"3","key":"6508_CR18","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1309\/8WYN-VUTG-V9RP-HUQH","volume":"121","author":"M Frost","year":"2004","unstructured":"Frost M, Newell J, Lones MA, Tripp SR, Cairo MS, Perkins SL (2004) Comparative immunohistochemical analysis of pediatric Burkitt lymphoma and diffuse large B-cell lymphoma. Am J Clin Pathol 121(3):384\u2013392. https:\/\/doi.org\/10.1309\/8WYN-VUTG-V9RP-HUQH","journal-title":"Am J Clin Pathol"},{"issue":"2","key":"6508_CR19","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1002\/hon.916","volume":"28","author":"C Bellan","year":"2010","unstructured":"Bellan C, Stefano L, Giulia de F, Rogena EA, Lorenzo L (2010) Burkitt lymphoma versus diffuse large B-cell lymphoma: a practical approach. Hematol Oncol 28(2):53\u201356. https:\/\/doi.org\/10.1002\/hon.916","journal-title":"Hematol Oncol"},{"issue":"11","key":"6508_CR20","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1182\/blood.V89.11.3909","volume":"89","author":"A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin\u2019s lymphoma","year":"1997","unstructured":"A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin\u2019s lymphoma (1997) The Non-Hodgkin\u2019s lymphoma classification project. Blood 89(11):3909\u20133918","journal-title":"Blood"},{"issue":"1","key":"6508_CR21","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1007\/s00428-022-03404-6","volume":"482","author":"RL King","year":"2023","unstructured":"King RL, Hsi ED, Chan WC, Piris MA, Cook JR, Scott DW et al (2023) Diagnostic approaches and future directions in Burkitt lymphoma and high-grade B-cell lymphoma. Virchows Arch 482(1):193\u2013205. https:\/\/doi.org\/10.1007\/s00428-022-03404-6","journal-title":"Virchows Arch"},{"key":"6508_CR22","doi-asserted-by":"crossref","unstructured":"McGowan-Jordan JHR, Moore S (eds) (2020) ISCN 2020: An International System for Human Cytogenomic Nomenclature (2020). S. Karger AG; 2020","DOI":"10.1159\/isbn.978-3-318-06867-2"},{"key":"6508_CR23","unstructured":"RP, KL (1987) Clustering by means of medoids. In: Dodge Y (ed) Statistical data analysis based on the L 1 norm and related methods. Elsevier Science, pp 405\u2013416"},{"issue":"8","key":"6508_CR24","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1097\/01.MP.0000024375.04135.2B","volume":"15","author":"M Berglund","year":"2002","unstructured":"Berglund M, Enblad G, Flordal E, Lui WO, Backlin C, Thunberg U et al (2002) Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization. Mod Pathol 15(8):807\u2013816. https:\/\/doi.org\/10.1097\/01.MP.0000024375.04135.2B","journal-title":"Mod Pathol"},{"issue":"2","key":"6508_CR25","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/leu.2008.281","volume":"23","author":"EG Boerma","year":"2009","unstructured":"Boerma EG, Siebert R, Kluin PM, Baudis M (2009) Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of todays knowledge. Leukemia 23(2):225\u2013234. https:\/\/doi.org\/10.1038\/leu.2008.281","journal-title":"Leukemia"},{"issue":"6","key":"6508_CR26","doi-asserted-by":"publisher","first-page":"2477","DOI":"10.1182\/blood-2005-07-2950","volume":"107","author":"W Chen","year":"2006","unstructured":"Chen W, Houldsworth J, Olshen AB, Nanjangud G, Chaganti S, Venkatraman ES et al (2006) Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomas. Blood 107(6):2477\u20132485. https:\/\/doi.org\/10.1182\/blood-2005-07-2950","journal-title":"Blood"},{"issue":"1","key":"6508_CR27","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1097\/QAI.0b013e3181d3d9eb","volume":"54","author":"KE Deffenbacher","year":"2010","unstructured":"Deffenbacher KE, Iqbal J, Liu Z, Fu K, Chan WC (2010) Recurrent chromosomal alterations in molecularly classified AIDS-related lymphomas: an integrated analysis of DNA copy number and gene expression. J Acquir Immune Defic Syndr 54(1):18\u201326. https:\/\/doi.org\/10.1097\/QAI.0b013e3181d3d9eb","journal-title":"J Acquir Immune Defic Syndr"},{"key":"6508_CR28","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1756-8722-5-54","volume":"5","author":"CA Tirado","year":"2012","unstructured":"Tirado CA, Chen W, Garcia R, Kohlman KA, Rao N (2012) Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large B-cell lymphoma: a review of the literature. J Hematol Oncol 5:54. https:\/\/doi.org\/10.1186\/1756-8722-5-54","journal-title":"J Hematol Oncol"},{"issue":"1","key":"6508_CR29","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1002\/gcc.22008","volume":"52","author":"V Havelange","year":"2013","unstructured":"Havelange V, Ameye G, Theate I, Callet-Bauchu E, Mugneret F, Michaux L et al (2013) Patterns of genomic aberrations suggest that Burkitt lymphomas with complex karyotype are distinct from other aggressive B-cell lymphomas with MYC rearrangement. Genes Chromosomes Cancer 52(1):81\u201392. https:\/\/doi.org\/10.1002\/gcc.22008","journal-title":"Genes Chromosomes Cancer"},{"issue":"6","key":"6508_CR30","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/gcc.22161","volume":"53","author":"E Maria Murga Penas","year":"2014","unstructured":"Maria Murga Penas E, Schilling G, Behrmann P, Klokow M, Vettorazzi E, Bokemeyer C et al (2014) Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples. Genes Chromosomes Cancer 53(6):497\u2013515. https:\/\/doi.org\/10.1002\/gcc.22161","journal-title":"Genes Chromosomes Cancer"},{"issue":"1","key":"6508_CR31","doi-asserted-by":"publisher","first-page":"61","DOI":"10.3324\/haematol.12986","volume":"94","author":"I Takeuchi","year":"2009","unstructured":"Takeuchi I, Tagawa H, Tsujikawa A, Nakagawa M, Katayama-Suguro M, Guo Y et al (2009) The potential of copy number gains and losses, detected by array-based comparative genomic hybridization, for computational differential diagnosis of B-cell lymphomas and genetic regions involved in lymphomagenesis. Haematologica 94(1):61\u201369. https:\/\/doi.org\/10.3324\/haematol.12986","journal-title":"Haematologica"},{"issue":"23","key":"6508_CR32","doi-asserted-by":"publisher","first-page":"8265","DOI":"10.1158\/1078-0432.CCR-05-1028","volume":"11","author":"Y Kasugai","year":"2005","unstructured":"Kasugai Y, Tagawa H, Kameoka Y, Morishima Y, Nakamura S, Seto M (2005) Identification of CCND3 and BYSL as candidate targets for the 6p21 amplification in diffuse large B-cell lymphoma. Clin Cancer Res 11(23):8265\u20138272. https:\/\/doi.org\/10.1158\/1078-0432.CCR-05-1028","journal-title":"Clin Cancer Res"},{"issue":"1","key":"6508_CR33","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1093\/annonc\/mds209","volume":"24","author":"D Soldini","year":"2013","unstructured":"Soldini D, Montagna C, Schuffler P, Martin V, Georgis A, Thiesler T et al (2013) A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome. Ann Oncol 24(1):193\u2013201. https:\/\/doi.org\/10.1093\/annonc\/mds209","journal-title":"Ann Oncol"},{"issue":"19","key":"6508_CR34","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1182\/blood.2019001880","volume":"134","author":"RI Panea","year":"2019","unstructured":"Panea RI, Love CL, Shingleton JR, Reddy A, Bailey JA, Moormann AM et al (2019) The whole-genome landscape of Burkitt lymphoma subtypes. Blood 134(19):1598\u20131607. https:\/\/doi.org\/10.1182\/blood.2019001880","journal-title":"Blood"},{"issue":"12","key":"6508_CR35","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1038\/leu.2011.156","volume":"25","author":"D Lenze","year":"2011","unstructured":"Lenze D, Leoncini L, Hummel M, Volinia S, Liu CG, Amato T et al (2011) The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma. Leukemia 25(12):1869\u20131876. https:\/\/doi.org\/10.1038\/leu.2011.156","journal-title":"Leukemia"},{"issue":"5","key":"6508_CR36","doi-asserted-by":"publisher","first-page":"e20038","DOI":"10.1371\/journal.pone.0020038","volume":"6","author":"S Moncini","year":"2011","unstructured":"Moncini S, Salvi A, Zuccotti P, Viero G, Quattrone A, Barlati S et al (2011) The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration. PLoS ONE 6(5):e20038. https:\/\/doi.org\/10.1371\/journal.pone.0020038","journal-title":"PLoS ONE"},{"issue":"2","key":"6508_CR37","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1002\/ijc.20733","volume":"114","author":"G Wrobel","year":"2005","unstructured":"Wrobel G, Roerig P, Kokocinski F, Neben K, Hahn M, Reifenberger G et al (2005) Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression. Int J Cancer 114(2):249\u2013256. https:\/\/doi.org\/10.1002\/ijc.20733","journal-title":"Int J Cancer"},{"issue":"3","key":"6508_CR38","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1002\/gcc.20632","volume":"48","author":"JJ Oudejans","year":"2009","unstructured":"Oudejans JJ, van Wieringen WN, Smeets SJ, Tijssen M, Vosse SJ, Meijer CJ et al (2009) Identification of genes putatively involved in the pathogenesis of diffuse large B-cell lymphomas by integrative genomics. Genes Chromosomes Cancer 48(3):250\u2013260. https:\/\/doi.org\/10.1002\/gcc.20632","journal-title":"Genes Chromosomes Cancer"},{"issue":"3","key":"6508_CR39","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1002\/ijc.10824","volume":"103","author":"ES Jordanova","year":"2003","unstructured":"Jordanova ES, Riemersma SA, Philippo K, Schuuring E, Kluin PM (2003) Beta2-microglobulin aberrations in diffuse large B-cell lymphoma of the testis and the central nervous system. Int J Cancer 103(3):393\u2013398. https:\/\/doi.org\/10.1002\/ijc.10824","journal-title":"Int J Cancer"},{"issue":"8","key":"6508_CR40","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.3324\/haematol.2021.279631","volume":"107","author":"A K\u00fcnstner","year":"2022","unstructured":"K\u00fcnstner A, Witte HM, Riedl J, Bernard V, St\u00f6lting S et al (2022) Mutational landscape of high-grade B-cell lymphoma with MYC-, BCL2 and\/or BCL6 rearrangements characterized by whole-exome sequencing. Haematologica 107(8):1850\u20131863. https:\/\/doi.org\/10.3324\/haematol.2021.279631","journal-title":"Haematologica"},{"issue":"12","key":"6508_CR41","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1038\/ng.2468","volume":"44","author":"C Love","year":"2012","unstructured":"Love C, Sun Z, Jima D, Li G, Zhang J, Miles R et al (2012) The genetic landscape of mutations in Burkitt lymphoma. Nat Genet 44(12):1321\u20131325. https:\/\/doi.org\/10.1038\/ng.2468","journal-title":"Nat Genet"},{"issue":"19","key":"6508_CR42","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1182\/blood.2019001880","volume":"134","author":"R Panea","year":"2019","unstructured":"Panea R, Love C, Shingleton JR, Reddy A, Bailey JA, Moormann AM et al (2019) The whole-genome landscape of Burkitt lymphoma subtypes. Blood 134(19):1598\u20131607. https:\/\/doi.org\/10.1182\/blood.2019001880","journal-title":"Blood"},{"issue":"7","key":"6508_CR43","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/modpathol.2010.76","volume":"23","author":"AC Seegmiller","year":"2010","unstructured":"Seegmiller AC, Garcia R, Huang R, Maleki A, Karandikar NJ, Chen W (2010) Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas. Mod Pathol 23(7):909\u2013920. https:\/\/doi.org\/10.1038\/modpathol.2010.76","journal-title":"Mod Pathol"},{"key":"6508_CR44","unstructured":"WHO classifcation of tumors Editorial Board Haematolymphoid tumours. Lyon (France): International Agency for Research on Cancer: 2024 (WHO Classification of Tumours series, 5TH ed., vol.11)"},{"issue":"1\u20132","key":"6508_CR45","doi-asserted-by":"publisher","first-page":"169","DOI":"10.3109\/10428199609067595","volume":"21","author":"I Slavutsky","year":"1996","unstructured":"Slavutsky I, Andreoli G, Gutierrez M, Narbaitz M, Lucero G, Eppinger M (1996) Variant (8;22) translocation in lymphoblastic lymphoma. Leuk Lymphoma 21(1\u20132):169\u2013172. https:\/\/doi.org\/10.3109\/10428199609067595","journal-title":"Leuk Lymphoma"},{"issue":"7","key":"6508_CR46","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1097\/01.MP.0000019577.73786.64","volume":"15","author":"N Nakamura","year":"2002","unstructured":"Nakamura N, Nakamine H, Tamaru J, Nakamura S, Yoshino T, Ohshima K et al (2002) The distinction between Burkitt lymphoma and diffuse large B-Cell lymphoma with c-myc rearrangement. Mod Pathol 15(7):771\u2013776. https:\/\/doi.org\/10.1097\/01.MP.0000019577.73786.64","journal-title":"Mod Pathol"},{"issue":"12","key":"6508_CR47","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/j.leukres.2004.04.010","volume":"28","author":"A Stoffel","year":"2004","unstructured":"Stoffel A, Filippa D, Rao PH (2004) The p73 locus is commonly deleted in non-Hodgkin\u2019s lymphomas. Leuk Res 28(12):1341\u20131345. https:\/\/doi.org\/10.1016\/j.leukres.2004.04.010","journal-title":"Leuk Res"},{"issue":"5","key":"6508_CR48","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1111\/bjh.17708","volume":"194","author":"JR Chapman","year":"2021","unstructured":"Chapman JR, Bouska AC, Zhang W, Alderuccio JP, Lossos IS, Rimsza et al (2021) EBV-positive HIV-associated diffuse large B cell lymphomas are characterized by JAK\/STAT (STAT3) pathway mutations and unique clinicopathologic features. Br J Haematol 194(5):870\u2013878. https:\/\/doi.org\/10.1111\/bjh.17708","journal-title":"Br J Haematol"},{"issue":"3","key":"6508_CR49","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1111\/j.1365-2141.1984.tb02913.x","volume":"57","author":"F Sigaux","year":"1984","unstructured":"Sigaux F, Berger R, Bernheim A, Valensi F, Daniel MT, Flandrin G (1984) Malignant lymphomas with band 8q24 chromosome abnormality: a morphologic continuum extending from burkitt\u2019s to immunoblastic lymphoma. Br J Haematol 57(3):393\u2013405. https:\/\/doi.org\/10.1111\/j.1365-2141.1984.tb02913.x","journal-title":"Br J Haematol"},{"issue":"1","key":"6508_CR50","doi-asserted-by":"publisher","first-page":"4001","DOI":"10.1038\/s41467-018-06354-3","volume":"9","author":"SE Arthur","year":"2018","unstructured":"Arthur SE, Jiang A, Grande BM, Alcaide M, Cojocaru R, Rushton CK et al (2018) Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma. Nat Commun 9(1):4001. https:\/\/doi.org\/10.1038\/s41467-018-06354-3","journal-title":"Nat Commun"},{"issue":"19","key":"6508_CR51","doi-asserted-by":"publisher","first-page":"2988","DOI":"10.1182\/blood-2013-07-517177","volume":"123","author":"J Zhang","year":"2014","unstructured":"Zhang J, Jima D, Moffitt AB, Liu Q, Czader M, Hsi ED et al (2014) The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. Blood 123(19):2988\u20132996. https:\/\/doi.org\/10.1182\/blood-2013-07-517177","journal-title":"Blood"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-025-06508-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-025-06508-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-025-06508-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T16:02:52Z","timestamp":1754668972000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-025-06508-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":51,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["6508"],"URL":"https:\/\/doi.org\/10.1007\/s00277-025-06508-6","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"type":"print","value":"0939-5555"},{"type":"electronic","value":"1432-0584"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"27 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}